Summary of project PR002422
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002422. The data can be accessed directly via it's Project DOI: 10.21228/M8K54D This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002422 |
| Project DOI: | doi: 10.21228/M8K54D |
| Project Title: | Mechanisms of Exogenous Metabolites Alter the Bactericidal Efficiency of Antibiotics by Affecting the Metabolic State of Bacteria |
| Project Summary: | Antibiotic resistance is a serious global crisis. Different from the traditional drug resistance mechanism, metabolic regulation can change bacteria from antibiotic resistant state to sensitive state, which provides a new way for antibiotics to treat the infection of resistant bacteria. In previous studies, we found that arginine can significantly improve the bactericidal efficiency of antibiotics, but the mechanism was not clear. We plan to study the effects of arginine on the global metabolic pathway from the perspective of metabolomics, and finally determine how arginine changes the bactericidal efficiency of antibiotics. |
| Institute: | Chinese Academy of Sciences |
| Last Name: | Wang |
| First Name: | Chao |
| Address: | NO.162 Jiefang Road, Jinan, China |
| Email: | wangchao850303@163.com |
| Phone: | 13075330325 |
Summary of all studies in project PR002422
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003866 | Impact of Exogenous Arginine Addition on the Bacterial Metabolome | Escherichia coli | Chinese Academy of Sciences | MS* | 2025-05-01 | 1 | 10 | Uploaded data (1.3G)* |
