Summary of project PR002433
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002433. The data can be accessed directly via it's Project DOI: 10.21228/M84Z62 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002433 |
| Project DOI: | doi: 10.21228/M84Z62 |
| Project Title: | PLCXD1 as a Regulator of Insulin-Stimulated Lipid Metabolism in Human Adipocytes |
| Project Summary: | Insulin regulates adipocyte biology through transcriptional and post-transcriptional mechanisms, yet many insulin-responsive targets remain poorly characterized. Phospholipase C X domain-containing protein-1 (PLCXD1) emerged as a regulator of insulin-stimulated lipogenesis, without affecting lipolysis or adipogenesis. Our findings establish PLCXD1 as an insulin-responsive effector of lipid metabolism, with implications for adipocyte dysfunction in insulin resistance. |
| Institute: | Helmholtz Centre for Environmental Research |
| Last Name: | Engelmann |
| First Name: | Beatrice |
| Address: | Permoserstr. 15 |
| Email: | beatrice.engelmann@ufz.de |
| Phone: | 00493412351099 |
Summary of all studies in project PR002433
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003879 | Establishing an insulin-sensitive human adipocyte culture model | Homo sapiens | Helmholtz Centre for Environmental Research | MS | 2025-05-21 | 1 | 12 | Uploaded data (36.2M)* |
