Summary of project PR002503
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002503. The data can be accessed directly via it's Project DOI: 10.21228/M83N9S This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002503 |
| Project DOI: | doi: 10.21228/M83N9S |
| Project Title: | Untargeted Metabolomics and In silico Screening of Sisymbrium officinale: Identification of Flavonoid Glycosides as Potential Anti-Inflammatory Agents |
| Project Summary: | Sisymbrium officinale (SO), often referred to as "the plant of singers," is a revered traditional Mediterranean medicinal herb known for its applications in treating inflammatory diseases. Despite its historical use, comprehensive metabolomics and in silico studies validating its anti-inflammatory effects remain scarce. The study reported here seeks to uncover and characterize the bioactive compounds within SO, providing a critical step in identifying potential anti-inflammatory agents. To achieve this, we extracted plant compounds using various solvents with differing polarities, i.e., water, methanol, ethanol, acetone, and chloroform. These extractions were followed by phase separation (polar phase and nonpolar phase) of crude extracts. Additionally, we employed GC-MS and LC-MS (polar phase and nonpolar phase) spectroscopy to obtain a preliminary quantification of the diverse functional groups in the SO extracts.We also carried out inflammatory bioassay analysis followed by chemometrics and in silico screening. |
| Institute: | King Abdullah University of Science and Technology |
| Last Name: | Kahfi |
| First Name: | Jordan |
| Address: | Thuwal, Thuwal, Makkah, 23955, Saudi Arabia |
| Email: | jordan.kahfi@kaust.edu.sa |
| Phone: | 0541244806 |
Summary of all studies in project PR002503
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST003998 | Untargeted Metabolomics and In silico Screening of Sisymbrium officinale: Identification of Flavonoid Glycosides as Potential Anti-Inflammatory Agents | Sisymbrium officinale | King Abdullah University of Science and Technology | MS | 2025-07-15 | 1 | 25 | Uploaded data (42.4G)* |
