Summary of project PR002516
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002516. The data can be accessed directly via it's Project DOI: 10.21228/M8DZ7X This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002516 |
| Project DOI: | doi: 10.21228/M8DZ7X |
| Project Title: | Untargeted Metabolomics Profiling of Human Plasma via LC-Q-TOF for sudden sensorineural hearing loss (SSNHL) Biomarker Discovery |
| Project Type: | Untargeted Metabolomics |
| Project Summary: | This project focuses on untargeted metabolomic analysis of human plasma samples using advanced mass spectrometry techniques (LC-MS). The goal is to (1) characterize the metabolic profile of human plasma; (2) identify potential biomarkers or metabolic pathways associated with sudden sensorineural hearing loss (SSNHL); (3) provide foundational metabolomic data for further biomedical research. Raw data, analytical methods, and metabolite annotations are submitted for transparency and reproducibility. In this study, non-targeted metabolomic analysis revealed that the differentially expressed metabolites in plasma of SSNHL patients mainly focus on lipid and lipid-like molecules, amino acids and their derivatives, flavonoids, as well as organic oxygen compounds involved in central carbon metabolism and energy metabolic pathways such as tricarboxylic acid cycle intermediates. |
| Institute: | The First Affiliated Hospital of Kunming Medical University |
| Last Name: | Zhang |
| First Name: | Huangruici |
| Address: | No. 295 Xichang Road, Kunming, Yunnan, 650032, China |
| Email: | 1031784375@qq.com |
| Phone: | 15508893380 |
Summary of all studies in project PR002516
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST004023 | Untargeted Metabolomics Profiling of Human Plasma via LC-Q-TOF for sudden sensorineural hearing loss (SSNHL) Biomarker Discovery | Homo sapiens | The First Affiliated Hospital of Kunming Medical University | MS* | 2025-07-28 | 1 | 117 | Uploaded data (27.6G)* |
