Summary of project PR002725
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002725. The data can be accessed directly via it's Project DOI: 10.21228/M8DV7W This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002725 |
| Project DOI: | doi: 10.21228/M8DV7W |
| Project Title: | Plasma metabolomics study on calorie restriction in rhesus macaques |
| Project Summary: | This project aimed to assess plasma metabolite concentrations using LC-MS in two cohorts of rhesus macaques. The ad-libitum (AL, n = 11) cohort consisted of animals fed without restriction, while the calorie-restricted (CR, n = 6) cohort received a diet restricted by up to 30% of their baseline intake. Plasma samples were collected at three time points: uninfected baseline (labeled in the study design as Ad-libitum and CR), 14 days post-SIV infection (labelled as Ad-libitum+SIV, CR+SIV), and 11 months post-ART (labelled as Ad-libitum+SIV+ART, CR+SIV+ART). LC-MS metabolomics was performed on all six CR animals at every time point. In the AL cohort, only six of the eleven animals were profiled due to the high cost of metabolomics; these same six animals were sampled at all time points to maintain consistency and enable statistical comparisons without confounding. |
| Institute: | Tulane National Biomedical Research Center |
| Department: | Immunology |
| Laboratory: | Joseph Mudd |
| Last Name: | Suresh Babu |
| First Name: | Naveen |
| Address: | 18703 Three Rivers Road, Covington, Louisiana, USA, 70433. |
| Email: | nsureshbabu@tulane.edu |
| Phone: | 4126264523 |
Summary of all studies in project PR002725
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST004309 | Metabolic reprogramming by caloric restriction enhances acute-phase virologic control and reduces chronic inflammation in SIV-infected rhesus macaques | Macaca mulatta | Tulane National Biomedical Research Center | MS | 2025-11-14 | 1 | 40 | Uploaded data (10.2G)* |
