Summary of project PR002780
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002780. The data can be accessed directly via it's Project DOI: 10.21228/M89S0M This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002780 |
| Project DOI: | doi: 10.21228/M89S0M |
| Project Title: | The structural and functional effects of plant protection products on the microbiota and host in honeybees (Apis mellifera) at environmentally relevant concentrations |
| Project Summary: | Plant protection products (PPPs) can reach a range of non-target organisms including pollinators such as honeybees. Even at sublethal concentrations these can influence the host physiology, development and behaviour. In this study we investigated the structural and functional effects of sublethal, environmentally relevant concentrations of PPPs on the honeybee microbiota, gut and brain, and how these potentially affect microbiota-microbiota and microbiota-host interactions. After an acute treatment we sampled an exposure timepoint three days after exposure followed by a post-exposure timepoint ten days after exposure to determine the permanence of the observed effects. Overall, this research provides novel insights into the effects of the tested products using a combination of proteomics, metabolomics, CT imaging and bioinformatic tools. |
| Institute: | Helmholtz Centre for Environmental Research |
| Department: | Molecular Toxicology |
| Last Name: | Engelmann |
| First Name: | Beatrice |
| Address: | Permoserstraße 15, Leipzipg, Saxony, 03418, Germany |
| Email: | beatrice.engelmann@ufz.de |
| Phone: | 004934160251099 |
Summary of all studies in project PR002780
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST004387 | Investigation of PPP-induced changes in the gut of honeybee workers using targeted metabolomics for SCFA determination. | Apis mellifera | Helmholtz Centre for Environmental Research | MS | 2025-12-15 | 1 | 430 | Uploaded data (85M)* |
| ST004408 (Available on 2025-12-22) | Investigation of PPP induced changes in the gut of honeybee workers using targeted metabolomics for amino acid and biogenic amine determination. | Apis mellifera | Helmholtz Centre for Environmental Research | MS | - | - | 432 | Not available |
| ST004428 (Available on 2025-12-29) | Investigation of PPP-induced changes in the brain of honeybee workers using targeted metabolomics for amino acid and biogenic amine determination. | Apis mellifera | Helmholtz Centre for Environmental Research | MS | - | - | 504 | Not available |
