Summary of project PR002793
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002793. The data can be accessed directly via it's Project DOI: 10.21228/M8N26R This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR002793 |
| Project DOI: | doi: 10.21228/M8N26R |
| Project Title: | Metabolomics in biotic stress: an example from potato powdery scab |
| Project Type: | MS-based non-targeted metabolomics |
| Project Summary: | Powdery scab, caused by the soilborne pathogen Spongospora subterranea, is a widespread and persistent disease affecting potato roots and tubers worldwide. The pathogen produces highly durable resting spores that can survive in soil for decades, complicating crop rotation and soil management strategies. Previous studies from our laboratory employed transcriptomics and proteomics to investigate cultivar-specific responses to infection. We observed that a set of glutathione S-transferase (GST) genes and proteins were consistently upregulated in the resistant cultivar Gladiator, whereas the susceptible cultivar Iwa showed minimal induction. The present study aimed to use untargeted metabolomics to examine root biochemical changes in resistant and susceptible potato cultivars following S. subterranea infection. The results identify clear differences in the metabolite profile of resistant and susceptible potato cultivars and demonstrate that cysteinyl-glycine accumulates only in the resistant potato cultivar during infection, providing further biochemical evidence that glutathione S-transferase-linked detoxification mediates resistance to Spongospora subterranea. |
| Institute: | University of Tasmania |
| Department: | Science and Engineering |
| Laboratory: | Central Science Laboratory |
| Last Name: | Wilson |
| First Name: | Richard |
| Address: | University of Tasmania Chemistry Building, Room 334, Dobson Rd, Sandy Bay, Hobart 7001, TAS, Australia |
| Email: | richard.wilson@utas.edu.au |
| Phone: | 0413535934 |
Summary of all studies in project PR002793
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST004422 | Metabolomics in biotic stress: an example from potato powdery scab | Solanum tuberosum | University of Tasmania | MS | 2025-12-15 | 1 | 17 | Uploaded data (3.7G)* |
