Summary of Study ST000004
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000004. The data can be accessed directly via it's Project DOI: 10.21228/M8MW26 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000004 |
| Study Title | Lipidomics studies on NIDDK / NIST human plasma samples |
| Study Type | MS analysis on human plasma |
| Study Summary | The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in collaboration with the National Institute of Standards (NIST) recently produced a human plasma standard reference material (SRM 1950) for metabolite analysis. The SRM was prepared by obtaining plasma samples from 100 individuals between 40 and 50 years of age, whose ethnicity was representative of the US population and that included an equal number of men and women. The intent of the NIDDK/NIST project was to provide a reference material that would be publically available to researchers and that could be used by the clinical chemistry community to identify plasma metabolites for diagnostic purposes. Signature metabolites could then be further probed for their usefulness as disease biomarkers. The LIPID MAPS Consortium has undertaken the task to analyze this SRM by systematically identifying and quantifying the lipid molecular species in the six main categories of mammalian lipids. The quantitative levels of over 500 different lipids present in this reference human plasma sample are presented here. |
| Institute | LIPID MAPS |
| Department | Multiple |
| Laboratory | Multiple |
| Last Name | Fahy |
| First Name | Eoin |
| Address | UCSD |
| efahy@ucsd.edu | |
| Submit Date | 2013-02-20 |
| Num Groups | 1 |
| Total Subjects | 100 |
| Num Males | 100 |
| Publications | Quehenberger, O. et al Lipidomics reveals a remarkable diversity of lipids in human plasma. J Lipid Res. 51, 3299-3305 (2010). |
| Raw Data Available | No |
| Analysis Type Detail | LC-MS |
| Release Date | 2013-03-17 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
| Project ID: | PR000004 |
| Project DOI: | doi: 10.21228/M8MW26 |
| Project Title: | LIPID MAPS Lipidomics studies |
| Project Type: | MS quantitative analysis |
| Project Summary: | Multi-center quantitative lipidomics studies on samples from human and murine sources (LIPIDMAPS) |
| Institute: | LIPID MAPS |
| Department: | Multiple |
| Laboratory: | Multiple |
| Last Name: | Fahy |
| First Name: | Eoin |
| Address: | UCSD |
| Email: | efahy@ucsd.edu |
| Funding Source: | NIGMS |
Subject:
| Subject ID: | SU000005 |
| Subject Type: | Human |
| Subject Species: | Homo sapiens |
| Taxonomy ID: | 9606 |
| Age Or Age Range: | 40-50 |
| Species Group: | Human |
Factors:
Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)
| mb_sample_id | local_sample_id | Pooled sample |
|---|---|---|
| SA000055 | NIDDK1 | yes |
| Showing results 1 to 1 of 1 |
Collection:
| Collection ID: | CO000004 |
| Collection Summary: | - |
| Sample Type: | Blood |
Treatment:
| Treatment ID: | TR000006 |
Sample Preparation:
| Sampleprep ID: | SP000004 |
| Sampleprep Summary: | - |
Combined analysis:
| Analysis ID | AN000004 | AN000005 | AN000006 | AN000007 | AN000008 | AN000009 | AN000010 | AN000011 |
|---|---|---|---|---|---|---|---|---|
| Analysis type | MS | MS | MS | MS | MS | MS | MS | MS |
| Chromatography type | ||||||||
| Chromatography system | ||||||||
| Column | ||||||||
| MS Type | ESI | ESI | ESI | ESI | ESI | ESI | ESI | ESI |
| MS instrument type | - | - | - | - | - | - | - | - |
| MS instrument name | - | - | - | - | - | - | - | - |
| Ion Mode | - | - | - | - | - | - | - | - |
| Units | pmol/ml | pmol/ml | nmol/ml | nmol/ml | pmol/ml | pmol/ml | pmol/ml | umol/ml |
Chromatography:
| Chromatography ID: | CH000004 |
MS:
| MS ID: | MS000004 |
| Analysis ID: | AN000004 |
| Instrument Name: | - |
| Instrument Type: | - |
| MS Type: | ESI |
| Ion Mode: | - |
| MS ID: | MS000005 |
| Analysis ID: | AN000005 |
| Instrument Name: | - |
| Instrument Type: | - |
| MS Type: | ESI |
| Ion Mode: | - |
| MS ID: | MS000006 |
| Analysis ID: | AN000006 |
| Instrument Name: | - |
| Instrument Type: | - |
| MS Type: | ESI |
| Ion Mode: | - |
| MS ID: | MS000007 |
| Analysis ID: | AN000007 |
| Instrument Name: | - |
| Instrument Type: | - |
| MS Type: | ESI |
| Ion Mode: | - |
| MS ID: | MS000008 |
| Analysis ID: | AN000008 |
| Instrument Name: | - |
| Instrument Type: | - |
| MS Type: | ESI |
| Ion Mode: | - |
| MS ID: | MS000009 |
| Analysis ID: | AN000009 |
| Instrument Name: | - |
| Instrument Type: | - |
| MS Type: | ESI |
| Ion Mode: | - |
| MS ID: | MS000010 |
| Analysis ID: | AN000010 |
| Instrument Name: | - |
| Instrument Type: | - |
| MS Type: | ESI |
| Ion Mode: | - |
| MS ID: | MS000011 |
| Analysis ID: | AN000011 |
| Instrument Name: | - |
| Instrument Type: | - |
| MS Type: | ESI |
| Ion Mode: | - |
