Summary of study ST000255

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000207. The data can be accessed directly via it's Project DOI: 10.21228/M8N30T This work is supported by NIH grant, U2C- DK119886.


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Study IDST000255
Study TitleNIH WCMC Pilot & Feasibility Project: “Metabolomics of Neonatal Pulmonary Hypertension” in human
Study TypeCase-control study
Study SummaryTargeted metabolomic analyses of oxylipins were performed on 40 human umbilical cord plasma samples collected from infants born prematurely (gestational age <37 weeks). Samples were analyzed by UPLC-MS/MS using a Waters Acquity UPLC and detected on an API 4000 QTrap (AB Sciex, Framingham, MA, USA) by multiple reaction monitoring (MRM) after negative mode electrospray ionization.
University of California, Davis
LaboratoryNewman Lab
Last NameNewman
First NameJohn
Address430 W. Health Sciences Dr., Davis, CA 95616
Submit Date2015-09-03
Num Groups4
Total Subjects16
Raw Data AvailableYes
Raw Data File Type(s).mzML
Uploaded File Size32 M
Analysis Type DetailLC-MS
Release Date2015-09-14
Release Version1
John Newman John Newman application/zip

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Project ID:PR000207
Project DOI:doi: 10.21228/M8N30T
Project Title:Metabolomics of Neonatal Pulmonary Hypertension (in Preterm Infants)
Project Type:Case-control study
Project Summary:This study aimed to determine metabolic patterns in cord blood associated with the development of pulmonary hypertension (PH) in human preterm infants. Umbilical cord blood was acquired from a nested case-control study of 20 premature (gestational age <37 weeks) infants with PH (cases) and 20 infants without PH (controls) selected from Prentice NICU birth cohort. Case and control infants were matched by race/ethnicity, gender, and gestational age. Archived cord blood plasma underwent metabolomics analysis.
Institute:University of California, Davis
Department:Department of Pediatrics, School of Medicine
Laboratory:Wedgwood lab
Last Name:Wedgwood
First Name:Stephen
Address:1002B, Research II, 4625 2nd Ave., Sacramento, CA 95817
Funding Source:National Institute of Health U24 DK092993