Summary of study ST000312

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000251. The data can be accessed directly via it's Project DOI: 10.21228/M8BG63 This work is supported by NIH grant, U2C- DK119886.


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Study IDST000312
Study TitleIDH1R132H activity in glioma cell lines and tumnor tissue (2HG)
Study TypeRegular
Study SummaryWe developed genetically engineered mice to generate brain tumors with especific genetic lessions. The animals were split in three groups: NRAS, P53 knockdown, IDH1-R132H and ATRX knock down (NPAID); NRAS, P53 knockdown, IDH1-R132H (NPI); NRAS, P53 knockdown, (NshP53). From these tumor we obtain and culture tumor cells growth like neurospheres and attached cells.
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Phone(734) 232-8175
Submit Date2015-03-05
Num Groups4
Total Subjects4
Analysis Type DetailLC-MS
Release Date2016-06-18
Release Version1
Maureen Kachman Maureen Kachman application/zip

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Project ID:PR000251
Project DOI:doi: 10.21228/M8BG63
Project Title:IDH1 gliomas
Project Summary:Analyze IDH1R132H activity in glioma cell lines and tumnor tissue
Institute:University of Michigan
Laboratory:Castro Lab
Last Name:Castro
First Name:Maria
Address:Ann Arbor, MI