Summary of Study ST000708

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000505. The data can be accessed directly via it's Project DOI: 10.21228/M8CW9P This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000708
Study TitleMetabolic effects of weight reduction of very low energy diet vs dietary counseling
Study TypeMS analysis
Study SummaryThe goal of the study is to assess the relative efficacy of a very low energy diet (VLED) using liquid meal replacement vs. standard of care dietary counseling and education (DCE) on the metabolic effects of weight reduction in the obese, subfertile population and assess ovulation and time to conception in these women. Subfertile women were recruited for this study. They completed an OGTT at baseline and again after completing a very low energy diet intervention.
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Emailmkachman@med.umich.edu
Phone(734) 232-8175
Submit Date2017-06-19
Num Groups5
Total Subjects12
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M8CW9P
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Project:

Project ID:PR000505
Project DOI:doi: 10.21228/M8CW9P
Project Title:Subfertility Study
Project Type:MS analysis
Project Summary:Assess the relative efficacy of a very low energy diet (VLED) using liquid meal replacement vs. standard of care dietary counseling and education (DCE) on the metabolic effects of weight reduction in the obese, subfertile population and assess ovulation and time to conception in these women.
Institute:University of Michigan
Department:UMich Internal Medicine
Laboratory:Burant Lab
Last Name:Burant
First Name:Chuck
Address:1500 E. Medical Center Drive Ann Arbor, MI 48109
Email:burantc@umich.edu
Phone:734 615-3481

Subject:

Subject ID:SU000731
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Species Group:Mammals

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id GROUP VISIT
SA039927S00020455POOLED POOLED
SA039928S00020329Standard visit 1
SA039929S00020326Standard visit 1
SA039930S00020316Standard visit 1
SA039931S00020318Standard visit 1
SA039932S00020314Standard visit 1
SA039933S00020330Standard visit 2
SA039934S00020315Standard visit 2
SA039935S00020319Standard visit 2
SA039936S00020317Standard visit 2
SA039937S00020327VLED visit 1
SA039938S00020324VLED visit 1
SA039939S00020312VLED visit 1
SA039940S00020310VLED visit 1
SA039941S00020322VLED visit 1
SA039942S00020320VLED visit 1
SA039943S00020328VLED visit 2
SA039944S00020321VLED visit 2
SA039945S00020311VLED visit 2
SA039946S00020313VLED visit 2
SA039947S00020323VLED visit 2
SA039948S00020325VLED visit 2
Showing results 1 to 22 of 22

Collection:

Collection ID:CO000725
Collection Summary:-

Treatment:

Treatment ID:TR000745
Treatment Summary:-

Sample Preparation:

Sampleprep ID:SP000738
Sampleprep Summary:-
Sampleprep Protocol Filename:A003_-_Untargeted_Metabolomics.pdf

Combined analysis:

Analysis ID AN001099 AN001100 AN001101 AN001102
Analysis type MS MS MS MS
Chromatography type Reversed phase Reversed phase Reversed phase Reversed phase
Chromatography system Agilent Agilent Shimadzu CTO-20A Nexera X2 Shimadzu CTO-20A Nexera X2
Column Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
MS Type ESI ESI ESI ESI
MS instrument type QTOF QTOF Triple TOF Triple TOF
MS instrument name Agilent 6530 QTOF Agilent 6530 QTOF ABI Sciex 5600+ TripleTOF ABI Sciex 5600+ TripleTOF
Ion Mode POSITIVE NEGATIVE NEGATIVE POSITIVE
Units peak area peak area peak area normalized peak area normalized

Chromatography:

Chromatography ID:CH000773
Instrument Name:Agilent
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Chromatography Type:Reversed phase
  
Chromatography ID:CH000774
Instrument Name:Shimadzu CTO-20A Nexera X2
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Column Temperature:55
Flow Rate:0.400uL/min
Solvent A:40% acetonitrile/60% water; 10 mM ammonium acetate
Solvent B:10% acetonitrile/5% water/85% isopropanol; 10 mM ammonium acetate
Chromatography Type:Reversed phase

MS:

MS ID:MS000994
Analysis ID:AN001099
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:POSITIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
  
MS ID:MS000995
Analysis ID:AN001100
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:NEGATIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
  
MS ID:MS000996
Analysis ID:AN001101
Instrument Name:ABI Sciex 5600+ TripleTOF
Instrument Type:Triple TOF
MS Type:ESI
Ion Mode:NEGATIVE
Analysis Protocol File:A004_-_Shotgun_Lipidomics.pdf
  
MS ID:MS000997
Analysis ID:AN001102
Instrument Name:ABI Sciex 5600+ TripleTOF
Instrument Type:Triple TOF
MS Type:ESI
Ion Mode:POSITIVE
Analysis Protocol File:A004_-_Shotgun_Lipidomics.pdf
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