Summary of study ST000721

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000518. The data can be accessed directly via it's Project DOI: 10.21228/M8Q68H This work is supported by NIH grant, U2C- DK119886.


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Study IDST000721
Study TitleMetabolomic Profiles of Recovery from Traumatic Brain Injury
Study TypeMS analysis
Study SummaryWe hypothesize that differences between the metabolome of TBI patients achieving full recovery at 3 months post-injury and those with protracted recovery will provide insights into the biology of recovery and yield novel biomarkers for predicting protracted recovery. To test our hypothesis, we will perform a case-control study examining the metabolomic profile of 128 TBI patients, 18 years and older, who either have complete functional recovery at 3 months post-injury or have functional decline at 3 months post-injury. Subjects were selected from an ongoing prospective cohort of traumatic brain injury (Head Injury Serum Markers for Assessing Response to Trauma, HeadSMART. Funding for HeadSMART was provided by ImmunArray.
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Submit Date2017-06-19
Num Groups71
Total Subjects128
Raw Data AvailableYes
Raw Data File Type(s).d
Analysis Type DetailLC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman application/zip

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Project ID:PR000518
Project DOI:doi: 10.21228/M8Q68H
Project Title:Metabolomic Profiles of Recovery from Traumatic Brain Injury
Project Type:MS analysis
Project Summary:Exploring the metabolome of TBI patients on the day of injury and at 3 months after injury
Institute:University of Michigan
Department:Emergency Medicine
Laboratory:Korley Lab
Last Name:Korley
First Name:Frederick
Address:Ann Arbor, MI