Summary of Study ST000726

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000523. The data can be accessed directly via it's Project DOI: 10.21228/M82D6X This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Perform statistical analysis  |  Show all samples  |  Show named metabolites  |  Download named metabolite data  |  Perform analysis on untargeted data  
Download mwTab file (text)   |  Download mwTab file(JSON)   |  Download data files (Contains raw data)
Study IDST000726
Study TitlePolycystic Ovarian Syndrome(PCOS) metabolomics
Study TypeMS analysis
Study SummaryWe intend to analyze 89 samples for Untargeted Metabolomics on patients with and without Polycystic Ovarian Syndrome(PCOS). Blood is drawn from patients at four different time points; 1st) 0 Timepoint at clamp 2nd) 270 Timepoint at clamp 3rd) 0 Timepoint at OGTT and 4th) 120 Timepoint at OGTT (a couple of samples were missing 120, but we included a 30 min sample and a 90 min sample and for some subjects OGTT samples are not included but not listed here). All samples are drawn in EDTA tubes at the Children's Hospital of Colorado. Collected blood is processed and frozen immediately at -80 degrees celcius.
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Emailmkachman@med.umich.edu
Phone(734) 232-8175
Submit Date2017-06-19
Num Groups15
Total Subjects24
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M82D6X
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Project:

Project ID:PR000523
Project DOI:doi: 10.21228/M82D6X
Project Title:Melanie Green Polycystic Ovarian Syndrome (PCOS) Metabolomics
Project Type:MS analysis
Project Summary:Untargeted Metabolomics Study 6530 PCOS
Institute:Children's Hospital Colorado
Department:Pediatric Endocrinology
Laboratory:Green Lab
Last Name:Green
First Name:Melanie
Address:Aurora, CO
Email:Melanie.Green@childrenscolorado.org
Phone:720-777-5743

Subject:

Subject ID:SU000749
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Species Group:Mammals

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id AGE Assay DISEASE_STATE Timepoint
SA040732S0002814612 BC TP Control -
SA040733S0002815412 BC TP Control -
SA040734S0002815512 BC TP Control 270
SA040735S0002814712 BC TP Control 270
SA040736S0002808012 BC TP PCOS -
SA040737S0002812812 BC TP PCOS -
SA040738S0002807712 BC TP PCOS -
SA040739S0002807812 BC TP PCOS 270
SA040740S0002808112 BC TP PCOS 270
SA040741S0002812912 BC TP PCOS 270
SA040742S0002815612 OGTT Control -
SA040743S0002814812 OGTT Control -
SA040744S0002814912 OGTT Control 120
SA040745S0002815712 OGTT Control 120
SA040746S0002808212 OGTT PCOS -
SA040747S0002813012 OGTT PCOS -
SA040748S0002807912 OGTT PCOS -
SA040749S0002808312 OGTT PCOS 120
SA040750S0002813112 OGTT PCOS 120
SA040751S0002814213 BC TP Control -
SA040752S0002815813 BC TP Control -
SA040753S0002814313 BC TP Control 270
SA040754S0002815913 BC TP Control 270
SA040755S0002813213 BC TP PCOS -
SA040756S0002813313 BC TP PCOS 270
SA040757S0002816013 OGTT Control -
SA040758S0002814413 OGTT Control -
SA040759S0002814513 OGTT Control 120
SA040760S0002816113 OGTT Control 120
SA040761S0002813413 OGTT PCOS -
SA040762S0002813513 OGTT PCOS 120
SA040763S0002815014 BC TP Control -
SA040764S0002815114 BC TP Control 270
SA040765S0002810814 BC TP PCOS -
SA040766S0002810914 BC TP PCOS 270
SA040767S0002815214 OGTT Control -
SA040768S0002815314 OGTT Control 120
SA040769S0002814015 BC TP Control -
SA040770S0002814115 BC TP Control 270
SA040771S0002808415 BC TP PCOS -
SA040772S0002810015 BC TP PCOS -
SA040773S0002809215 BC TP PCOS -
SA040774S0002812415 BC TP PCOS -
SA040775S0002811615 BC TP PCOS -
SA040776S0002811015 BC TP PCOS -
SA040777S0002807315 BC TP PCOS -
SA040778S0002813615 BC TP PCOS -
SA040779S0002809615 BC TP PCOS -
SA040780S0002812515 BC TP PCOS 270
SA040781S0002813715 BC TP PCOS 270
SA040782S0002811715 BC TP PCOS 270
SA040783S0002811115 BC TP PCOS 270
SA040784S0002810115 BC TP PCOS 270
SA040785S0002809715 BC TP PCOS 270
SA040786S0002807415 BC TP PCOS 270
SA040787S0002808515 BC TP PCOS 270
SA040788S0002809315 BC TP PCOS 270
SA040789S0002813815 OGTT PCOS -
SA040790S0002809815 OGTT PCOS -
SA040791S0002808615 OGTT PCOS -
SA040792S0002809415 OGTT PCOS -
SA040793S0002810215 OGTT PCOS -
SA040794S0002807515 OGTT PCOS -
SA040795S0002811815 OGTT PCOS -
SA040796S0002812615 OGTT PCOS -
SA040797S0002811915 OGTT PCOS 120
SA040798S0002808715 OGTT PCOS 120
SA040799S0002810315 OGTT PCOS 120
SA040800S0002812715 OGTT PCOS 120
SA040801S0002809915 OGTT PCOS 120
SA040802S0002807615 OGTT PCOS 120
SA040803S0002809515 OGTT PCOS 30
SA040804S0002813915 OGTT PCOS 90
SA040805S0002808816 BC TP PCOS -
SA040806S0002812016 BC TP PCOS -
SA040807S0002811216 BC TP PCOS -
SA040808S0002808916 BC TP PCOS 270
SA040809S0002811316 BC TP PCOS 270
SA040810S0002812116 BC TP PCOS 270
SA040811S0002809016 OGTT PCOS -
SA040812S0002812216 OGTT PCOS -
SA040813S0002811416 OGTT PCOS -
SA040814S0002811516 OGTT PCOS 120
SA040815S0002812316 OGTT PCOS 120
SA040816S0002809116 OGTT PCOS 120
SA040817S0002810417 BC TP PCOS -
SA040818S0002810517 BC TP PCOS 270
SA040819S0002810617 OGTT PCOS -
SA040820S0002810717 OGTT PCOS 120
Showing results 1 to 89 of 89

Collection:

Collection ID:CO000743
Collection Summary:-
Sample Type:Blood

Treatment:

Treatment ID:TR000763
Treatment Summary:-

Sample Preparation:

Sampleprep ID:SP000756
Sampleprep Summary:-
Sampleprep Protocol Filename:A003_-_Untargeted_Metabolomics.pdf

Combined analysis:

Analysis ID AN001138 AN001139
Analysis type MS MS
Chromatography type Reversed phase Reversed phase
Chromatography system Agilent Agilent
Column Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
MS Type ESI ESI
MS instrument type QTOF QTOF
MS instrument name Agilent 6530 QTOF Agilent 6530 QTOF
Ion Mode NEGATIVE POSITIVE
Units peak area normalized peak area normalized

Chromatography:

Chromatography ID:CH000799
Instrument Name:Agilent
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Chromatography Type:Reversed phase

MS:

MS ID:MS001033
Analysis ID:AN001138
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:NEGATIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
  
MS ID:MS001034
Analysis ID:AN001139
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:POSITIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
  logo