Summary of study ST000734

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000531. The data can be accessed directly via it's Project DOI: 10.21228/M81H4W This work is supported by NIH grant, U2C- DK119886.


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Study IDST000734
Study TitleMeasuring SCFA in mice gut following colonization by C. difficile
Study TypeMS analysis
Study Summary3 cages of 5-8 week old C57B/6 mice were placed on the antibiotic cefoperazone for 10 days followed by 2 days of reovery on plain water. One cage remained on plain water the entire time. Of the three antibiotic treated cages. One was mock infected (uninfected control), one was infected with C. difficile strain VPI 10463, while the other was infected with C. difficile strain 630. Twenty-four hours after the infection the mice were eutanized and the ceal content was collected and snap frozen in liquid nitrogen. Samples were stored in the -80 until analysis.
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Phone(734) 232-8175
Submit Date2017-06-19
Num Groups4
Total Subjects4
Raw Data AvailableYes
Raw Data File Type(s).d
Analysis Type DetailGC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman application/zip

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Project ID:PR000531
Project DOI:doi: 10.21228/M81H4W
Project Title:SCFA During Infection
Project Type:MS analysis
Project Summary:Measuring SCFA following 24hr colonization by either C. difficile strain 630 or strain VPI. Compared to uninfected mice.
Institute:University of Michigan
Department:Internal Medicine
Laboratory:Young Lab
Last Name:Young
First Name:Vincent
Address:Ann Arbor, MI