Summary of Study ST000742

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000535. The data can be accessed directly via it's Project DOI: 10.21228/M8HH47 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000742
Study TitleMetabolite-phenotype link in X-linked Adrenoleukodystrophy (part II)
Study TypeMS analysis
Study SummaryUntargeted metabolomics of control, AMN and ALD patient-derived fibroblasts. Human Postmortem brain tissue were obtained from NICHD Brain Bank. Brain regions were directed by the neuropathologist at Henry Ford Health System and sample tissue were immediately frozen at -80C until shipping to the UMICH Core.
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Emailmkachman@med.umich.edu
Phone(734) 232-8175
Submit Date2017-06-19
Num Groups9
Total Subjects3
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M8HH47
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Project:

Project ID:PR000535
Project DOI:doi: 10.21228/M8HH47
Project Title:Metabolite-phenotype link in X-linked Adrenoleukodystrophy
Project Type:MS analysis
Project Summary:Untargeted metabolomics of control, AMN and ALD patient-derived fibroblasts
Institute:Henry Ford Health System
Department:Neurology
Laboratory:Singh Lab
Last Name:Singh
First Name:Jaspreet
Address:Detroit, MI
Email:jsingh2@hfhs.org
Phone:313-916-7725

Subject:

Subject ID:SU000765
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Species Group:Mammals

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Species TYPE
SA041188S00019605Homo sapiens Healthy control
SA041189S00019611Homo sapiens Healthy control
SA041190S00019610Homo sapiens Healthy control
SA041191S00019606Homo sapiens Healthy control
SA041192S00019608Homo sapiens Healthy control
SA041193S00019609Homo sapiens Healthy control
SA041194S00019607Homo sapiens Healthy control
SA041195S00019622Homo sapiens NLA
SA041196S00019627Homo sapiens NLA
SA041197S00019621Homo sapiens NLA
SA041198S00019630Homo sapiens NLA
SA041199S00019614Homo sapiens NLA
SA041200S00019628Homo sapiens NLA
SA041201S00019629Homo sapiens NLA
SA041202S00019623Homo sapiens PL
SA041203S00019624Homo sapiens PL
SA041204S00019617Homo sapiens PL
SA041205S00019616Homo sapiens PL
SA041206S00019613Homo sapiens PL
SA041207S00019631Homo sapiens PL
SA041208S00019618Homo sapiens PL
SA041209S00019634Homo sapiens PLS
SA041210S00019632Homo sapiens PLS
SA041211S00019633Homo sapiens PLS
SA041212S00019625Homo sapiens PLS
SA041213S00019626Homo sapiens PLS
SA041214S00019615Homo sapiens PLS
SA041215S00019612Homo sapiens PLS
SA041216S00019620Homo sapiens PLS
SA041217S00019619Homo sapiens PLS
SA041218S00019639Mus musculus ALD-KO
SA041219S00019640Mus musculus ALD-KO
SA041220S00019638Mus musculus ALD-KO
SA041221S00019643Mus musculus KO-M
SA041222S00019642Mus musculus KO-M
SA041223S00019641Mus musculus KO-M
SA041224S00019635Mus musculus WT
SA041225S00019636Mus musculus WT
SA041226S00019637Mus musculus WT
SA041187S00020156- -
Showing results 1 to 40 of 40

Collection:

Collection ID:CO000759
Collection Summary:-
Sample Type:Brain

Treatment:

Treatment ID:TR000779
Treatment Summary:-

Sample Preparation:

Sampleprep ID:SP000772
Sampleprep Summary:-
Sampleprep Protocol Filename:A003_-_Untargeted_Metabolomics.pdf

Combined analysis:

Analysis ID AN001157 AN001158
Analysis type MS MS
Chromatography type Reversed phase Reversed phase
Chromatography system Agilent Agilent
Column Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
MS Type ESI ESI
MS instrument type QTOF QTOF
MS instrument name Agilent 6530 QTOF Agilent 6530 QTOF
Ion Mode NEGATIVE POSITIVE
Units peak area normalized peak area normalized

Chromatography:

Chromatography ID:CH000816
Instrument Name:Agilent
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Chromatography Type:Reversed phase

MS:

MS ID:MS001052
Analysis ID:AN001157
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:NEGATIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
  
MS ID:MS001053
Analysis ID:AN001158
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:POSITIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
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