Summary of Study ST000744

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000537. The data can be accessed directly via it's Project DOI: 10.21228/M8809S This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000744
Study TitleMetabolomics of intensive weight management clinic (IWMC) weight loss
Study TypeMS analysis
Study SummaryHuman patients were enrolled in a weight loss clinic and followed. Patients were male and female, normoglycemic,pre-diabetic and diabetic and with and without neuropathy.
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Emailmkachman@med.umich.edu
Phone(734) 232-8175
Submit Date2017-06-19
Num Groups7
Total Subjects3
Raw Data AvailableYes
Raw Data File Type(s)wiff
Analysis Type DetailLC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M8809S
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Project:

Project ID:PR000537
Project DOI:doi: 10.21228/M8809S
Project Title:Callaghan IWMC plasma baseline
Project Type:MS analysis
Project Summary:Obesity study with intervention
Institute:University of Michigan
Department:Neurology
Laboratory:Feldman Lab
Last Name:Feldman
First Name:Eva
Address:Ann Arbor, MI
Email:efeldman@umich.edu
Phone:734-763-7274

Subject:

Subject ID:SU000767
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Species Group:Mammals

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Gender Glycemic status Neuropathy
SA041241S00025597female Diabetic Neuropathy
SA041242S00025603female Diabetic Neuropathy
SA041243S00025583female Diabetic no neuropathy
SA041244S00025600female Diabetic no neuropathy
SA041245S00025596female Pre-diabetic Neuropathy
SA041246S00025601female Pre-diabetic Neuropathy
SA041247S00025599female Pre-diabetic Neuropathy
SA041248S00025585female Pre-diabetic Neuropathy
SA041249S00025592female Pre-diabetic no neuropathy
SA041250S00025595female Pre-diabetic no neuropathy
SA041251S00025591female Pre-diabetic no neuropathy
SA041252S00025586female Pre-diabetic no neuropathy
SA041253S00025604male Diabetic Neuropathy
SA041254S00025598male Diabetic Neuropathy
SA041255S00025588male Diabetic Neuropathy
SA041256S00025594male Diabetic no neuropathy
SA041257S00025589male Diabetic no neuropathy
SA041258S00025602male Diabetic no neuropathy
SA041259S00025582male Normoglycemic Neuropathy
SA041260S00025587male Normoglycemic Neuropathy
SA041261S00025593male Normoglycemic no neuropathy
SA041262S00025584male Normoglycemic no neuropathy
SA041263S00025607male Pre-diabetic Neuropathy
SA041264S00025605male Pre-diabetic Neuropathy
SA041265S00025590male Pre-diabetic no neuropathy
SA041266S00025606male Pre-diabetic no neuropathy
Showing results 1 to 26 of 26

Collection:

Collection ID:CO000761
Collection Summary:-

Treatment:

Treatment ID:TR000781
Treatment Summary:-

Sample Preparation:

Sampleprep ID:SP000774
Sampleprep Summary:-
Sampleprep Protocol Filename:A003_-_Untargeted_Metabolomics.pdf

Combined analysis:

Analysis ID AN001163 AN001164 AN001165 AN001166
Analysis type MS MS MS MS
Chromatography type Reversed phase Reversed phase Reversed phase Reversed phase
Chromatography system Agilent Agilent Shimadzu CTO-20A Nexera X2 Shimadzu CTO-20A Nexera X2
Column Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
MS Type ESI ESI ESI ESI
MS instrument type QTOF QTOF Triple TOF Triple TOF
MS instrument name Agilent 6530 QTOF Agilent 6530 QTOF ABI Sciex 5600+ TripleTOF ABI Sciex 5600+ TripleTOF
Ion Mode POSITIVE NEGATIVE NEGATIVE POSITIVE
Units peak area normalized peak area normalized peak area normalized peak area normalized

Chromatography:

Chromatography ID:CH000819
Instrument Name:Agilent
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Chromatography Type:Reversed phase
  
Chromatography ID:CH000820
Instrument Name:Shimadzu CTO-20A Nexera X2
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Column Temperature:55
Flow Rate:0.400uL/min
Solvent A:40% acetonitrile/60% water; 10 mM ammonium acetate
Solvent B:10% acetonitrile/5% water/85% isopropanol; 10 mM ammonium acetate
Chromatography Type:Reversed phase

MS:

MS ID:MS001058
Analysis ID:AN001163
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:POSITIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
  
MS ID:MS001059
Analysis ID:AN001164
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:NEGATIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
  
MS ID:MS001060
Analysis ID:AN001165
Instrument Name:ABI Sciex 5600+ TripleTOF
Instrument Type:Triple TOF
MS Type:ESI
Ion Mode:NEGATIVE
Analysis Protocol File:A004_-_Shotgun_Lipidomics.pdf
  
MS ID:MS001061
Analysis ID:AN001166
Instrument Name:ABI Sciex 5600+ TripleTOF
Instrument Type:Triple TOF
MS Type:ESI
Ion Mode:POSITIVE
Analysis Protocol File:A004_-_Shotgun_Lipidomics.pdf
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