Summary of Study ST000758

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000547. The data can be accessed directly via it's Project DOI: 10.21228/M8ZH48 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000758
Study TitleEffects of caloric restriction in HCR/LCR rats
Study TypeMS analysis
Study SummaryOne year caloric restriction (CR) compared to ad lib (AL) feeding on metabolic and clinical parameters to assess association with intrinsic oxidative capacity. High and low capacity running rats (HCR and LCR) were randomized to ad lib feeding vs. 40% caloric restriction starting at 8 weeks of age. Experiment was continued for 52 weeks when blood and tissue were collected. Exercise capacity, CLAMS assessment of fuel utilization and clinical parameters were determined at 8 weeks, 8 months and 12 months of age. Tissue was collected in the fed (2 hours after re-feeding) or fasted stated all groups.
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Emailmkachman@med.umich.edu
Phone(734) 232-8175
Submit Date2017-06-19
Num Groups7
Total Subjects5
Raw Data AvailableYes
Raw Data File Type(s)wiff
Analysis Type DetailLC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M8ZH48
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Project:

Project ID:PR000547
Project DOI:doi: 10.21228/M8ZH48
Project Title:Caloric Restriction and Oxidative capactiy in rats
Project Type:MS analysis
Project Summary:One year caloric restriction compared to ad lib feeding on metabolic and clinical parameters to assess association with intrinsic oxidative capacity
Institute:University of Michigan
Department:Internal Medicine
Laboratory:Burant Lab
Last Name:Burant
First Name:Chuck
Address:1500 E. Medical Center Drive Ann Arbor, MI 48109
Email:burantc@umich.edu
Phone:734 615-3481

Subject:

Subject ID:SU000781
Subject Type:Rat
Subject Species:Rattus norvegicus
Taxonomy ID:10116
Species Group:Mammals

Factors:

Subject type: Rat; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id local_sample_id Feeding Group
SA041612S00018548Fast HCR-AL
SA041613S00018549Fast HCR-AL
SA041614S00018550Fast HCR-AL
SA041615S00018551Fast HCR-AL
SA041616S00018552Fast HCR-AL
SA041617S00018571Fast HCR-CR
SA041618S00018570Fast HCR-CR
SA041619S00018573Fast HCR-CR
SA041620S00018572Fast HCR-CR
SA041621S00018574Fast HCR-CR
SA041622S00018575Fast HCR-CR
SA041623S00018538Fast LCR-AL
SA041624S00018537Fast LCR-AL
SA041625S00018536Fast LCR-AL
SA041626S00018539Fast LCR-AL
SA041627S00018540Fast LCR-AL
SA041628S00018541Fast LCR-AL
SA041629S00018560Fast LCR-CR
SA041630S00018561Fast LCR-CR
SA041631S00018563Fast LCR-CR
SA041632S00018562Fast LCR-CR
SA041633S00018559Fast LCR-CR
SA041634S00018558Fast LCR-CR
SA041635S00018553Fed HCR-AL
SA041636S00018555Fed HCR-AL
SA041637S00018554Fed HCR-AL
SA041638S00018557Fed HCR-AL
SA041639S00018556Fed HCR-AL
SA041640S00018577Fed HCR-CR
SA041641S00018576Fed HCR-CR
SA041642S00018578Fed HCR-CR
SA041643S00018580Fed HCR-CR
SA041644S00018579Fed HCR-CR
SA041645S00018581Fed HCR-CR
SA041646S00018543Fed LCR-AL
SA041647S00018542Fed LCR-AL
SA041648S00018544Fed LCR-AL
SA041649S00018547Fed LCR-AL
SA041650S00018545Fed LCR-AL
SA041651S00018546Fed LCR-AL
SA041652S00018565Fed LCR-CR
SA041653S00018564Fed LCR-CR
SA041654S00018566Fed LCR-CR
SA041655S00018567Fed LCR-CR
SA041656S00018568Fed LCR-CR
SA041657S00018569Fed LCR-CR
SA041658S00020152Pooled plasma Pooled plasma
Showing results 1 to 47 of 47

Collection:

Collection ID:CO000775
Collection Summary:-

Treatment:

Treatment ID:TR000795
Treatment Summary:-

Sample Preparation:

Sampleprep ID:SP000788
Sampleprep Summary:-
Sampleprep Protocol Filename:A003_-_Untargeted_Metabolomics.pdf

Chromatography:

Chromatography ID:CH000835
Instrument Name:Agilent
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Chromatography Type:Reversed phase
  
Chromatography ID:CH000836
Instrument Name:Shimadzu CTO-20A Nexera X2
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Column Temperature:55
Flow Rate:0.400uL/min
Solvent A:40% acetonitrile/60% water; 10 mM ammonium acetate
Solvent B:10% acetonitrile/5% water/85% isopropanol; 10 mM ammonium acetate
Chromatography Type:Reversed phase

Analysis:

Analysis ID:AN001190
Analysis Type:MS
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
Instrument Name:6530 Q-TOF LC/MS (Agilent)
Chromatography ID:CH000835
Num Factors:9
Num Metabolites:327
Has Mz:1
Has Rt:1
Rt Units:Minutes
Units:peak area
  
Analysis ID:AN001191
Analysis Type:MS
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
Instrument Name:6530 Q-TOF LC/MS (Agilent)
Chromatography ID:CH000835
Num Factors:9
Num Metabolites:452
Has Mz:1
Has Rt:1
Rt Units:Minutes
Units:peak area
  
Analysis ID:AN001192
Analysis Type:MS
Analysis Protocol File:A004_-_Shotgun_Lipidomics.pdf
Instrument Name:TripleTOF 5600+ (Absciex)
Chromatography ID:CH000836
Num Factors:9
Num Metabolites:17
Units:peak area normalized
  
Analysis ID:AN001193
Analysis Type:MS
Analysis Protocol File:A004_-_Shotgun_Lipidomics.pdf
Instrument Name:TripleTOF 5600+ (Absciex)
Chromatography ID:CH000836
Num Factors:9
Num Metabolites:186
Units:peak area normalized
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