Summary of Study ST000759

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000548. The data can be accessed directly via it's Project DOI: 10.21228/M8TT2C This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000759
Study TitleAge and exercise effect on metabolomics in rats
Study TypeMS analysis
Study SummaryN/NIH rats were selected for either low (LRT) or high (HRT) response to training. Rats at 2 year of age were trained for 8 weeks with an improvement in oxidative capacity. Selection was also performed for high (HCR) or low (LCR) intrinsic running capacity. Young and old animals are compared to 12 week old animals.
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Emailmkachman@med.umich.edu
Phone(734) 232-8175
Submit Date2017-06-19
Num Groups12
Total Subjects46
Raw Data AvailableYes
Raw Data File Type(s)wiff
Analysis Type DetailLC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M8TT2C
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Project:

Project ID:PR000548
Project DOI:doi: 10.21228/M8TT2C
Project Title:Oxidative Capacity and Metabolic Health
Project Type:MS analysis
Project Summary:To investigate the relationship between oxidative capacity and metabolic health
Institute:University of Michigan
Department:Internal Medicine
Laboratory:Burant Lab
Last Name:Burant
First Name:Chuck
Address:1500 E. Medical Center Drive Ann Arbor, MI 48109
Email:burantc@umich.edu
Phone:734 615-3481

Subject:

Subject ID:SU000782
Subject Type:Rat
Subject Species:Rattus norvegicus
Taxonomy ID:10116
Species Group:Mammal

Factors:

Subject type: Rat; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id local_sample_id Age Line Sex Training
SA041659S00020828106 week HRT Female no
SA041660S00020829106 week HRT Female no
SA041661S00020827106 week HRT Female no
SA041662S00020826106 week HRT Female no
SA041663S00020824106 week HRT Female yes
SA041664S00020825106 week HRT Female yes
SA041665S00020822106 week HRT Female yes
SA041666S00020823106 week HRT Female yes
SA041667S00020819106 week LRT Female no
SA041668S00020818106 week LRT Female no
SA041669S00020820106 week LRT Female no
SA041670S00020821106 week LRT Female no
SA041671S00020815106 week LRT Female yes
SA041672S00020814106 week LRT Female yes
SA041673S00020817106 week LRT Female yes
SA041674S00020816106 week LRT Female yes
SA041675S00020847126 week HCR Male no
SA041676S00020846126 week HCR Male no
SA041677S00020848126 week HCR Male no
SA041678S00020849126 week HCR Male no
SA041679S00020843126 week LCR Male no
SA041680S00020842126 week LCR Male no
SA041681S00020845126 week LCR Male no
SA041682S00020844126 week LCR Male no
SA041683S0002085914 week HCR Male no
SA041684S0002085614 week HCR Male no
SA041685S0002085714 week HCR Male no
SA041686S0002085814 week HCR Male no
SA041687S0002085514 week HCR Male no
SA041688S0002085414 week LCR Male no
SA041689S0002085014 week LCR Male no
SA041690S0002085214 week LCR Male no
SA041691S0002085314 week LCR Male no
SA041692S0002085114 week LCR Male no
SA041693S000208374 week HCR Male no
SA041694S000208414 week HCR Male no
SA041695S000208364 week HCR Male no
SA041696S000208384 week HCR Male no
SA041697S000208394 week HCR Male no
SA041698S000208404 week HCR Male no
SA041699S000208314 week LCR Male no
SA041700S000208304 week LCR Male no
SA041701S000208324 week LCR Male no
SA041702S000208354 week LCR Male no
SA041703S000208344 week LCR Male no
SA041704S000208334 week LCR Male no
Showing results 1 to 46 of 46

Collection:

Collection ID:CO000776
Collection Summary:-

Treatment:

Treatment ID:TR000796
Treatment Summary:-

Sample Preparation:

Sampleprep ID:SP000789
Sampleprep Summary:-
Sampleprep Protocol Filename:A003_-_Untargeted_Metabolomics.pdf

Combined analysis:

Analysis ID AN001194 AN001195 AN001196 AN001197
Analysis type MS MS MS MS
Chromatography type Reversed phase Reversed phase Reversed phase Reversed phase
Chromatography system Agilent Agilent Shimadzu CTO-20A Nexera X2 Shimadzu CTO-20A Nexera X2
Column Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
MS Type ESI ESI ESI ESI
MS instrument type QTOF QTOF Triple TOF Triple TOF
MS instrument name Agilent 6530 QTOF Agilent 6530 QTOF ABI Sciex 5600+ TripleTOF ABI Sciex 5600+ TripleTOF
Ion Mode NEGATIVE POSITIVE NEGATIVE POSITIVE
Units peak area normalized peak area normalized peak area normalized peak area normalized

Chromatography:

Chromatography ID:CH000837
Instrument Name:Agilent
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Chromatography Type:Reversed phase
  
Chromatography ID:CH000838
Instrument Name:Shimadzu CTO-20A Nexera X2
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Column Temperature:55
Flow Rate:0.400uL/min
Solvent A:40% acetonitrile/60% water; 10 mM ammonium acetate
Solvent B:10% acetonitrile/5% water/85% isopropanol; 10 mM ammonium acetate
Chromatography Type:Reversed phase

MS:

MS ID:MS001089
Analysis ID:AN001194
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:NEGATIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
  
MS ID:MS001090
Analysis ID:AN001195
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:POSITIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
  
MS ID:MS001091
Analysis ID:AN001196
Instrument Name:ABI Sciex 5600+ TripleTOF
Instrument Type:Triple TOF
MS Type:ESI
Ion Mode:NEGATIVE
Analysis Protocol File:A004_-_Shotgun_Lipidomics.pdf
  
MS ID:MS001092
Analysis ID:AN001197
Instrument Name:ABI Sciex 5600+ TripleTOF
Instrument Type:Triple TOF
MS Type:ESI
Ion Mode:POSITIVE
Analysis Protocol File:A004_-_Shotgun_Lipidomics.pdf
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