Summary of Study ST000762
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000550. The data can be accessed directly via it's Project DOI: 10.21228/M8K96J This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000762 |
| Study Title | Plasma Nucleotide/adenosine concentrations in patiens with scleroderma depending on exercise |
| Study Type | MS analysis |
| Study Summary | This experiment was performed using the following cohorts: 1) healthy controls, 2) patients with scleroderma at low risk for pulmonary hypertension, 3) pateints with scleroderma at high risk for pulmonary hypertension (SSc Cath). Whole blood was drawn directly into stop soilution (1:1 ratio) at rest and again at peak exercise for each human subject. The samples were processed to plasma by MCRU and stored at -80 in the Biorepository. |
| Institute | University of Michigan |
| Department | Biomedical Research Core Facilities |
| Laboratory | Metabolomics core |
| Last Name | Kachman |
| First Name | Maureen |
| Address | 6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714 |
| mkachman@med.umich.edu | |
| Phone | (734) 232-8175 |
| Submit Date | 2017-06-19 |
| Num Groups | 5 |
| Total Subjects | 26 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | LC-MS |
| Release Date | 2017-12-06 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
| Project ID: | PR000550 |
| Project DOI: | doi: 10.21228/M8K96J |
| Project Title: | Scleroderma and exercise |
| Project Type: | MS analysis |
| Project Summary: | Plasma Nucleotide/adenosine concentrations in patiens with scleroderma depending on exercise |
| Institute: | University of Michigan |
| Department: | Internal Medicine-Cardiology |
| Laboratory: | Visovatti Lab |
| Last Name: | Visovatti |
| First Name: | Scott |
| Address: | Ann Arbor, MI |
| Email: | shv@med.umich.edu |
| Phone: | 734-657-6917 |
Subject:
| Subject ID: | SU000785 |
| Subject Type: | Human |
| Subject Species: | Homo sapiens |
| Taxonomy ID: | 9606 |
| Species Group: | Mammals |
Factors:
Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)
| mb_sample_id | local_sample_id | Exercise | Group |
|---|---|---|---|
| SA041720 | S00019114 | No | Healthy |
| SA041721 | S00019110 | No | Healthy |
| SA041722 | S00019108 | No | Healthy |
| SA041723 | S00019118 | No | Healthy |
| SA041724 | S00019120 | No | Healthy |
| SA041725 | S00019138 | No | Healthy |
| SA041726 | S00019132 | No | Healthy |
| SA041727 | S00019106 | No | Healthy |
| SA041728 | S00019116 | No | Healthy |
| SA041729 | S00019093 | No | Low Risk SSc |
| SA041730 | S00019112 | No | Low Risk SSc |
| SA041731 | S00019122 | No | Low Risk SSc |
| SA041732 | S00019130 | No | Low Risk SSc |
| SA041733 | S00019097 | No | Low Risk SSc |
| SA041734 | S00019091 | No | Low Risk SSc |
| SA041735 | S00019124 | No | SSc Cath |
| SA041736 | S00019128 | No | SSc Cath |
| SA041737 | S00019126 | No | SSc Cath |
| SA041738 | S00019134 | No | SSc Cath |
| SA041739 | S00019103 | No | SSc Cath |
| SA041740 | S00019140 | No | SSc Cath |
| SA041741 | S00019101 | No | SSc Cath |
| SA041742 | S00019105 | No | SSc Cath |
| SA041743 | S00019099 | No | SSc Cath |
| SA041744 | S00019136 | No | SSc Cath |
| SA041745 | S00019095 | No | SSc Cath |
| SA041746 | S00019133 | Yes | Healthy |
| SA041747 | S00019139 | Yes | Healthy |
| SA041748 | S00019121 | Yes | Healthy |
| SA041749 | S00019115 | Yes | Healthy |
| SA041750 | S00019119 | Yes | Healthy |
| SA041751 | S00019111 | Yes | Healthy |
| SA041752 | S00019109 | Yes | Healthy |
| SA041753 | S00019117 | Yes | Healthy |
| SA041754 | S00019107 | Yes | Healthy |
| SA041755 | S00019092 | Yes | Low Risk SSc |
| SA041756 | S00019098 | Yes | Low Risk SSc |
| SA041757 | S00019094 | Yes | Low Risk SSc |
| SA041758 | S00019131 | Yes | Low Risk SSc |
| SA041759 | S00019113 | Yes | Low Risk SSc |
| SA041760 | S00019123 | Yes | Low Risk SSc |
| SA041761 | S00019104 | Yes | SSc Cath |
| SA041762 | S00019102 | Yes | SSc Cath |
| SA041763 | S00019141 | Yes | SSc Cath |
| SA041764 | S00019096 | Yes | SSc Cath |
| SA041765 | S00019100 | Yes | SSc Cath |
| SA041766 | S00019137 | Yes | SSc Cath |
| SA041767 | S00019125 | Yes | SSc Cath |
| SA041768 | S00019135 | Yes | SSc Cath |
| SA041769 | S00019129 | Yes | SSc Cath |
| SA041770 | S00019127 | Yes | SSc Cath |
| Showing results 1 to 51 of 51 |
Collection:
| Collection ID: | CO000779 |
| Collection Summary: | - |
| Sample Type: | Blood |
Treatment:
| Treatment ID: | TR000799 |
| Treatment Summary: | - |
Sample Preparation:
| Sampleprep ID: | SP000792 |
| Sampleprep Summary: | - |
| Sampleprep Protocol Filename: | A011_-_Glycolysis-TCA-nucleotides.pdf |
Combined analysis:
| Analysis ID | AN001200 |
|---|---|
| Analysis type | MS |
| Chromatography type | HILIC |
| Chromatography system | Agilent |
| Column | Phenomenex Luna NH2 (150 x 1mm,3um) |
| MS Type | ESI |
| MS instrument type | QTOF |
| MS instrument name | Agilent 6520B QTOF |
| Ion Mode | NEGATIVE |
| Units | nM |
Chromatography:
| Chromatography ID: | CH000841 |
| Instrument Name: | Agilent |
| Column Name: | Phenomenex Luna NH2 (150 x 1mm,3um) |
| Flow Rate: | 0.075 mL/min |
| Solvent A: | 100% water; 5 mM ammonium acetate, pH 9.9 |
| Solvent B: | 100% acetonitrile |
| Chromatography Type: | HILIC |
MS:
| MS ID: | MS001095 |
| Analysis ID: | AN001200 |
| Instrument Name: | Agilent 6520B QTOF |
| Instrument Type: | QTOF |
| MS Type: | ESI |
| Ion Mode: | NEGATIVE |
| Analysis Protocol File: | A011_-_Glycolysis-TCA-nucleotides.pdf |
