Summary of Study ST001355
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000925. The data can be accessed directly via it's Project DOI: 10.21228/M8497W This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST001355 |
Study Title | Influence of propylparaben in children |
Study Summary | Exposure to paraben was associated with allergic outcomes, partially through the metabolomics changes. Urinary metabolomic analysis can be useful to elucidate the mechanisms underlying the associations between exposure to paraben and allergic outcomes. |
Institute | Seoul National University College of Medicine and Hospital |
Department | Department of Clinical Pharmacology and Therapeutics |
Last Name | Lee |
First Name | Yujin |
Address | 101 Daehak-ro, Jongno-gu, Seoul 110-799, Korea |
yoojinlee@snu.ac.kr | |
Phone | +821033804686 |
Submit Date | 2020-03-28 |
Raw Data Available | Yes |
Raw Data File Type(s) | smp |
Analysis Type Detail | GC-MS |
Release Date | 2021-03-28 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
Project ID: | PR000925 |
Project DOI: | doi: 10.21228/M8497W |
Project Title: | Metabolomics linking propyl paraben exposure and allergic outcomes. |
Project Summary: | we evaluated the biomarkers and pathways involved in the associations between urine propyl paraben levels and outcomes by applying global metabolomics analysis. |
Institute: | Seoul National University College of Medicine and Hospital |
Department: | Department of Clinical Pharmacology and Therapeutics |
Last Name: | Lee |
First Name: | Yujin |
Address: | 101 Daehak-ro, Jongno-gu, Seoul 110-799, Korea |
Email: | yoojinlee@snu.ac.kr |
Phone: | +821033804686 |
Subject:
Subject ID: | SU001429 |
Subject Type: | Human |
Subject Species: | Homo sapiens |
Taxonomy ID: | 9606 |
Gender: | Male and female |
Factors:
Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)
mb_sample_id | local_sample_id | Group | S_Gender |
---|---|---|---|
SA098371 | 39 | Control | F |
SA098372 | 38 | Control | F |
SA098373 | 40 | Control | F |
SA098374 | 37 | Control | F |
SA098375 | 41 | Control | F |
SA098376 | 43 | Control | F |
SA098377 | 70 | Control | F |
SA098378 | 32 | Control | F |
SA098379 | 73 | Control | F |
SA098380 | 33 | Control | F |
SA098381 | 74 | Control | F |
SA098382 | 44 | Control | F |
SA098383 | 36 | Control | F |
SA098384 | 47 | Control | F |
SA098385 | 55 | Control | F |
SA098386 | 54 | Control | F |
SA098387 | 56 | Control | F |
SA098388 | 78 | Control | F |
SA098389 | 58 | Control | F |
SA098390 | 53 | Control | F |
SA098391 | 52 | Control | F |
SA098392 | 48 | Control | F |
SA098393 | 30 | Control | F |
SA098394 | 77 | Control | F |
SA098395 | 50 | Control | F |
SA098396 | 51 | Control | F |
SA098397 | 45 | Control | F |
SA098398 | 29 | Control | F |
SA098399 | 11 | Control | F |
SA098400 | 10 | Control | F |
SA098401 | 13 | Control | F |
SA098402 | 90 | Control | F |
SA098403 | 68 | Control | F |
SA098404 | 1 | Control | F |
SA098405 | 8 | Control | F |
SA098406 | 3 | Control | F |
SA098407 | 2 | Control | F |
SA098408 | 5 | Control | F |
SA098409 | 6 | Control | F |
SA098410 | 7 | Control | F |
SA098411 | 59 | Control | F |
SA098412 | 88 | Control | F |
SA098413 | 24 | Control | F |
SA098414 | 23 | Control | F |
SA098415 | 67 | Control | F |
SA098416 | 72 | Control | F |
SA098417 | 28 | Control | F |
SA098418 | 27 | Control | F |
SA098419 | 22 | Control | F |
SA098420 | 21 | Control | F |
SA098421 | 18 | Control | F |
SA098422 | 17 | Control | F |
SA098423 | 19 | Control | F |
SA098424 | 20 | Control | F |
SA098425 | 75 | Control | M |
SA098426 | 76 | Control | M |
SA098427 | 71 | Control | M |
SA098428 | 83 | Control | M |
SA098429 | 86 | Control | M |
SA098430 | 87 | Control | M |
SA098431 | 89 | Control | M |
SA098432 | 91 | Control | M |
SA098433 | 85 | Control | M |
SA098434 | 84 | Control | M |
SA098435 | 80 | Control | M |
SA098436 | 81 | Control | M |
SA098437 | 82 | Control | M |
SA098438 | 79 | Control | M |
SA098439 | 61 | Control | M |
SA098440 | 25 | Control | M |
SA098441 | 26 | Control | M |
SA098442 | 31 | Control | M |
SA098443 | 34 | Control | M |
SA098444 | 16 | Control | M |
SA098445 | 14 | Control | M |
SA098446 | 69 | Control | M |
SA098447 | 4 | Control | M |
SA098448 | 9 | Control | M |
SA098449 | 12 | Control | M |
SA098450 | 35 | Control | M |
SA098451 | 15 | Control | M |
SA098452 | 64 | Control | M |
SA098453 | 65 | Control | M |
SA098454 | 42 | Control | M |
SA098455 | 66 | Control | M |
SA098456 | 62 | Control | M |
SA098457 | 63 | Control | M |
SA098458 | 57 | Control | M |
SA098459 | 49 | Control | M |
SA098460 | 46 | Control | M |
SA098461 | 60 | Control | M |
SA098462 | 141 | Exposured | F |
SA098463 | 143 | Exposured | F |
SA098464 | 142 | Exposured | F |
SA098465 | 145 | Exposured | F |
SA098466 | 147 | Exposured | F |
SA098467 | 138 | Exposured | F |
SA098468 | 146 | Exposured | F |
SA098469 | 130 | Exposured | F |
SA098470 | 149 | Exposured | F |
Collection:
Collection ID: | CO001424 |
Collection Summary: | urine samples were collected from Korean children. |
Sample Type: | Urine |
Treatment:
Treatment ID: | TR001444 |
Treatment Summary: | No treatment was performed on the samples. |
Sample Preparation:
Sampleprep ID: | SP001437 |
Sampleprep Summary: | A 50 µL sample of urine was extracted with 1mL of the first extraction solution. and the supernatant was dried under nitrogen and re-extracted with 400 µL of second extraction solution. After the second extraction, the supernatant was dried under nitrogen and further derivatized. |
Combined analysis:
Analysis ID | AN002254 |
---|---|
Analysis type | MS |
Chromatography type | GC |
Chromatography system | Agilent 7890B |
Column | Restek Rtx-5Sil (30m x 0.25mm,0.25um) |
MS Type | EI |
MS instrument type | GC-TOF |
MS instrument name | Leco Pegasus HT TOF |
Ion Mode | POSITIVE |
Units | intensity |
Chromatography:
Chromatography ID: | CH001656 |
Instrument Name: | Agilent 7890B |
Column Name: | Restek Rtx-5Sil (30m x 0.25mm,0.25um) |
Chromatography Type: | GC |
MS:
MS ID: | MS002098 |
Analysis ID: | AN002254 |
Instrument Name: | Leco Pegasus HT TOF |
Instrument Type: | GC-TOF |
MS Type: | EI |
MS Comments: | - |
Ion Mode: | POSITIVE |