Summary of Study ST001378

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000943. The data can be accessed directly via it's Project DOI: 10.21228/M8ST1P This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

Perform statistical analysis  |  Show all samples  |  Show named metabolites  |  Download named metabolite data  
Download mwTab file (text)   |  Download mwTab file(JSON)   |  Download data files (Contains raw data)
Study IDST001378
Study TitleGlobal metabolomics of COPD2020
Study SummaryTo discover distinctive endogenous metabotype of patients with COPD associated with TB from those originated from Tabaco smoking. Cross-sectional metabolomic analyses of serum samples were performed for subjects including TB-associated COPD (T-COPD), smoking-associated COPD (S-COPD) and healthy subjects. To retain a broad spectrum of metabolites, technically distinct analyses (global metabolomic profiling using liquid chromatography quadrupole time-of-flight mass spectrometry) were employed. Frozen samples were diluted with either an acetonitrile:methanol:water (3:3:4) mixture. Each sample (5 μL) was loaded onto an C18 column and was analyzed using an Agilent 6530 QTOF mass spectrometer (Agilent Technologies). Detailed protocol is obtained in this project
Institute
Seoul National University Hospital
Last NameKim
First NameDa jung
AddressDaehak-ro 101, Seoul, South Korea
Emaildkim3193@snu.ac.kr
Phone+82100
Submit Date2020-05-05
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2020-11-15
Release Version1
Da jung Kim Da jung Kim
https://dx.doi.org/10.21228/M8ST1P
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Project:

Project ID:PR000943
Project DOI:doi: 10.21228/M8ST1P
Project Title:COPD_2020
Project Summary:To discover distinctive endogenous metabotype of patients with COPD associated with TB from those originated from Tabaco smoking. Cross-sectional metabolomic analyses of serum samples were performed for subjects including TB-associated COPD (T-COPD), smoking-associated COPD (S-COPD) and healthy subjects. To retain a broad spectrum of metabolites, technically distinct analyses (global metabolomic profiling using liquid chromatography quadrupole time-of-flight mass spectrometry) were employed.
Institute:Seoul National University Hospital
Last Name:KIM
First Name:DA JUNG
Address:Daehak-ro 101, Seoul, South Korea
Email:dkim3193@snu.ac.kr
Phone:+82100

Subject:

Subject ID:SU001452
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Diagnosis
SA100698COPD_35COPD
SA100699COPD_36COPD
SA100700COPD_34COPD
SA100701COPD_33COPD
SA100702COPD_32COPD
SA100703COPD_37COPD
SA100704COPD_39COPD
SA100705COPD_42COPD
SA100706COPD_43COPD
SA100707COPD_41COPD
SA100708COPD_40COPD
SA100709COPD_31COPD
SA100710COPD_38COPD
SA100711COPD_30COPD
SA100712COPD_22COPD
SA100713COPD_23COPD
SA100714COPD_21COPD
SA100715COPD_20COPD
SA100716COPD_19COPD
SA100717COPD_24COPD
SA100718COPD_25COPD
SA100719COPD_29COPD
SA100720COPD_28COPD
SA100721COPD_27COPD
SA100722COPD_26COPD
SA100723COPD_44COPD
SA100724COPD_46COPD
SA100725COPD_63COPD
SA100726COPD_64COPD
SA100727COPD_62COPD
SA100728COPD_61COPD
SA100729COPD_60COPD
SA100730COPD_65COPD
SA100731COPD_66COPD
SA100732COPD_70COPD
SA100733COPD_71COPD
SA100734COPD_69COPD
SA100735COPD_68COPD
SA100736COPD_67COPD
SA100737COPD_59COPD
SA100738COPD_58COPD
SA100739COPD_50COPD
SA100740COPD_51COPD
SA100741COPD_49COPD
SA100742COPD_47COPD
SA100743COPD_18COPD
SA100744COPD_52COPD
SA100745COPD_53COPD
SA100746COPD_57COPD
SA100747COPD_56COPD
SA100748COPD_55COPD
SA100749COPD_54COPD
SA100750COPD_45COPD
SA100751COPD_48COPD
SA100752COPD_07COPD
SA100753COPD_08COPD
SA100754COPD_03COPD
SA100755COPD_02COPD
SA100756COPD_17COPD
SA100757COPD_01COPD
SA100758COPD_09COPD
SA100759COPD_06COPD
SA100760COPD_14COPD
SA100761COPD_15COPD
SA100762COPD_10COPD
SA100763COPD_13COPD
SA100764COPD_16COPD
SA100765COPD_12COPD
SA100766COPD_11COPD
SA100767NC_15NC
SA100768NC_13NC
SA100769NC_12NC
SA100770NC_16NC
SA100771NC_18NC
SA100772NC_20NC
SA100773NC_19NC
SA100774NC_11NC
SA100775NC_17NC
SA100776NC_02NC
SA100777NC_04NC
SA100778NC_03NC
SA100779NC_21NC
SA100780NC_05NC
SA100781NC_06NC
SA100782NC_09NC
SA100783NC_08NC
SA100784NC_07NC
SA100785NC_10NC
SA100786NC_14NC
SA100787NC_34NC
SA100788NC_33NC
SA100789NC_32NC
SA100790NC_31NC
SA100791NC_35NC
SA100792NC_37NC
SA100793NC_22NC
SA100794NC_39NC
SA100795NC_38NC
SA100796NC_30NC
SA100797NC_36NC
Showing page 1 of 2     Results:    1  2  Next     Showing results 1 to 100 of 168

Collection:

Collection ID:CO001447
Collection Summary:Serum samples of COPD, TOPD and normal control
Sample Type:Blood (serum)

Treatment:

Treatment ID:TR001467
Treatment Summary:No treatment required

Sample Preparation:

Sampleprep ID:SP001460
Sampleprep Summary:Frozen samples were thawed at 4 °C, and 50 μL of each sample was diluted with 80% methanol (high-performance liquid chromatography grade, Millipore, Bedford, MA, USA).

Combined analysis:

Analysis ID AN002298
Analysis type MS
Chromatography type Reversed phase
Chromatography system Agilent 1290 Infinity
Column Waters Acquity BEH C18 (100 x 2mm,1.7um)
MS Type ESI
MS instrument type QTOF
MS instrument name Agilent 6530 QTOF
Ion Mode NEGATIVE
Units log(relative intensity)

Chromatography:

Chromatography ID:CH001688
Instrument Name:Agilent 1290 Infinity
Column Name:Waters Acquity BEH C18 (100 x 2mm,1.7um)
Chromatography Type:Reversed phase

MS:

MS ID:MS002141
Analysis ID:AN002298
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
MS Comments:DATA processed by Mass Hunter qualitatiy analysis or Profinder
Ion Mode:NEGATIVE
  logo