Summary of Study ST002000

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001269. The data can be accessed directly via it's Project DOI: 10.21228/M8PD9N This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002000
Study TitleA case-control study on plasma metabolomics analysis in Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) (Part 1)
Study SummaryTargeted and untargeted metabolomics analysis consisting of 888 metabolic analytes covering primary metabolites, biogenic amines, complex lipids, and oxylipins in 106 ME/CFS cases and 91 frequency-matched healthy controls.
Institute
Columbia University
DepartmentCenter for Infection and Immunity
LaboratoryCenter for Infection and Immunity
Last NameLipkin
First NameW. Ian
Address722 W. 168th St., 17th Floor, New York, NY, 10032
Emailwil2001@cumc.columbia.edu
Phone212-342-9033
Submit Date2021-11-22
Raw Data AvailableYes
Raw Data File Type(s)cdf
Analysis Type DetailGC-MS
Release Date2021-12-08
Release Version1
W. Ian Lipkin W. Ian Lipkin
https://dx.doi.org/10.21228/M8PD9N
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Project:

Project ID:PR001269
Project DOI:doi: 10.21228/M8PD9N
Project Title:Case-control study on plasma metabolomics analysis in Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
Project Summary:Targeted and untargeted metabolomics analysis consisting of 888 metabolic analytes covering primary metabolites, biogenic amines, complex lipids, and oxylipins in 106 ME/CFS cases and 91 frequency-matched healthy controls.
Institute:Columbia University
Department:Center for Infection and Immunity
Last Name:Lipkin
First Name:W. Ian
Address:722 W. 168th St., 17th Floor, New York, NY, 10032
Email:wil2001@cumc.columbia.edu
Phone:212-342-9033
Funding Source:This study was funded by National Institutes of Health U54 AI138370 (Center for Solutions for ME/CFS)

Subject:

Subject ID:SU002081
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Species Group:Mammals

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id treatment
SA186828GH025_157case
SA186829GH024_156case
SA186830CD067_084case
SA186831CD064_082case
SA186832CD065_083case
SA186833CD073_089case
SA186834CD074_090case
SA186835GH019_153case
SA186836GH017_152case
SA186837GH021_154case
SA186838GH022_155case
SA186839CD075_091case
SA186840CD076_092case
SA186841CD063_081case
SA186842CD059_079case
SA186843CD039_064case
SA186844GH053_170case
SA186845GH054_171case
SA186846CD035_061case
SA186847GH058_173case
SA186848CD041_066case
SA186849GH049_168case
SA186850CD055_077case
SA186851GH037_161case
SA186852CD053_076case
SA186853GH040_164case
SA186854GH042_166case
SA186855CD083_097case
SA186856AB003_001case
SA186857EF031_123case
SA186858EF032_124case
SA186859EF029_122case
SA186860EF028_121case
SA186861EF024_118case
SA186862EF026_119case
SA186863EF033_125case
SA186864EF034_126case
SA186865EF043_131case
SA186866GH002-2_142case
SA186867EF041_130case
SA186868GH004_143case
SA186869EF035_127case
SA186870EF023_117case
SA186871EF020_116case
SA186872EF004_105case
SA186873EF005_106case
SA186874EF003_104case
SA186875EF001_102case
SA186876GH060_174case
SA186877GH008_146case
SA186878EF010_110case
SA186879EF017_114case
SA186880EF019_115case
SA186881EF013_113case
SA186882EF012_112case
SA186883EF011_111case
SA186884CD084_098case
SA186885CD043_068case
SA186886IJ043_189case
SA186887AB047_026case
SA186888IJ044_190case
SA186889IJ046_191case
SA186890AB037_020case
SA186891IJ047_192case
SA186892AB049_027case
SA186893AB050_028case
SA186894IJ013_184case
SA186895IJ009_182case
SA186896IJ014_185case
SA186897AB055_031case
SA186898IJ030_187case
SA186899CD030_058case
SA186900AB036_019case
SA186901AB034_018case
SA186902AB010_006case
SA186903AB012_007case
SA186904AB009-2_005case
SA186905AB008_004case
SA186906AB004_002case
SA186907AB006_003case
SA186908AB014_008case
SA186909AB017_009case
SA186910IJ052_194case
SA186911IJ049_193case
SA186912IJ059_195case
SA186913AB023_011case
SA186914AB022_010case
SA186915IJ006_181case
SA186916AB052_030case
SA186917CD016_048case
SA186918CD015_047case
SA186919CD014_046case
SA186920IJ001_178case
SA186921CD001-2_038case
SA186922CD019-2_050case
SA186923CD027_056case
SA186924CD024_053case
SA186925CD022_052case
SA186926CD020_051case
SA186927CD011_044case
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Collection:

Collection ID:CO002074
Collection Summary:Human plasma were collected and flash-frozen.
Sample Type:Blood (plasma)

Treatment:

Treatment ID:TR002093
Treatment Summary:blinded

Sample Preparation:

Sampleprep ID:SP002087
Sampleprep Summary:Human plasma from cases and controls were collected and flash-frozen.

Chromatography:

Chromatography ID:CH002407
Chromatography Summary:Gas Chromatography conditions: A 30 m long, 0.25 mm i.d. Rtx-5Sil MS column (0.25 μm 95% dimethyl 5% diphenyl polysiloxane film) with additional 10 m integrated guard column is used (Restek, Bellefonte PA). 99.9999% pure Helium with built-in purifier (Airgas, Radnor PA) is set at constant flow of 1 ml/min. The oven temperature is held constant at 50°C for 1 min and then ramped at 20°C/min to 330°C at which it is held constant for 5 min.
Instrument Name:Gerstel CIS4 –with dual MPS Injector/ Agilent 6890 GC- Pegasus III TOF MS
Column Name:Rtx-5Sil MS
Chromatography Type:GC

Analysis:

Analysis ID:AN003263
Analysis Type:MS
Chromatography ID:CH002407
Num Factors:2
Num Metabolites:99
Units:normalized peak height
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