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ST003297 Metabolomic profiling of cultured TRAMP-C2 cells in the presence or absence of PD-L1.
Limit by pathway class:
Metabolic
Disease
Drug Action
Drug Metabolism
Physiological
Signaling
All
Minimum # of metabolites per pathway:
1
2
3
4
5
Pathway name (# of metabolites detected in this study)
HMDB pathway
KEGG pathway
Alanine Metabolism (6)
SMP0000055
map00250
Amino Sugar Metabolism (14)
SMP0000045
map00520
Ammonia Recycling (12)
SMP0000009
map00910
Androgen and Estrogen Metabolism (2)
SMP0000068
map00150
Androstenedione Metabolism (2)
SMP0030406
-
Arachidonic Acid Metabolism (3)
SMP0000075
map00590
Arginine and Proline Metabolism (13)
SMP0000020
map00330
Aspartate Metabolism (14)
SMP0000067
map00250
beta-Alanine Metabolism (11)
SMP0000007
map00410
Beta-Alanine Metabolism (1)
SMP0000007
map00410
Betaine Metabolism (5)
SMP0000123
map00260
Beta Oxidation of Very Long Chain Fatty Acids (3)
SMP0000052
map01040
Bile Acid Biosynthesis (6)
SMP0000035
map00120
Biotin Metabolism (1)
SMP0000066
map00780
Butyrate Metabolism (7)
SMP0000073
map00650
Caffeine Metabolism (3)
SMP0000028
map00232
Cardiolipin Biosynthesis (3)
SMP0020986
-
Carnitine Synthesis (3)
SMP0000465
-
Catecholamine Biosynthesis (2)
SMP0000012
map00350
Citric Acid Cycle (10)
SMP0000057
map00020
Cysteine Metabolism (7)
SMP0000013
map00270
D-Arginine and D-Ornithine Metabolism (1)
SMP0000036
map00472
De Novo Triacylglycerol Biosynthesis (2)
SMP0015896
-
Estrone Metabolism (2)
SMP0030880
-
Ethanol Degradation (4)
SMP0000449
-
Fatty Acid Biosynthesis (4)
SMP0000456
-
Fatty Acid Elongation in Mitochondria (2)
SMP0000054
map00062
Fatty Acid Metabolism (5)
SMP0000051
map00071
Folate Metabolism (4)
SMP0000053
map00670
Fructose and Mannose Degradation (5)
SMP0000064
map00051
Galactose Metabolism (5)
SMP0000043
map00052
Gluconeogenesis (14)
SMP0000128
map00010
Glucose-Alanine Cycle (4)
SMP0000127
-
Glutamate Metabolism (17)
SMP0000072
map00250
Glutathione Metabolism (7)
SMP0000015
map00480
Glycerolipid Metabolism (5)
SMP0000039
map00561
Glycerol Phosphate Shuttle (4)
SMP0000124
-
Glycine and Serine Metabolism (17)
SMP0000004
map00260
Glycolysis (10)
SMP0000040
map00010
Histidine Metabolism (7)
SMP0000044
map00340
Homocysteine Degradation (4)
SMP0000455
-
Inositol Metabolism (2)
SMP0000011
map00562
Inositol Phosphate Metabolism (2)
SMP0000462
map00562
Ketone Body Metabolism (4)
SMP0000071
map00072
Lactose Degradation (1)
SMP0000457
-
Lactose Synthesis (5)
SMP0000444
-
Lysine Degradation (6)
SMP0000037
map00310
Malate-Aspartate Shuttle (5)
SMP0000129
-
Methionine Metabolism (11)
SMP0000033
map00270
Methylhistidine Metabolism (1)
SMP0000715
-
Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids (5)
SMP0000482
-
Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty Acids (5)
SMP0000481
-
Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids (5)
SMP0000480
-
Mitochondrial Electron Transport Chain (6)
SMP0000355
map00190
Nicotinate and Nicotinamide Metabolism (8)
SMP0000048
map00760
Nucleotide Sugars Metabolism (5)
SMP0000010
map00520
Oxidation of Branched Chain Fatty Acids (6)
SMP0000030
-
Oxidation of Branched-Chain Fatty Acids (6)
SMP0000030
-
Pantothenate and CoA Biosynthesis (5)
SMP0000027
map00770
Pentose Phosphate Pathway (12)
SMP0000031
map00030
Phenylacetate Metabolism (4)
SMP0000126
map00360
Phenylalanine and Tyrosine Metabolism (11)
SMP0000008
map00360
Phosphatidylcholine Biosynthesis (3)
SMP0014212
-
Phosphatidylethanolamine Biosynthesis (4)
SMP0029731
-
Phosphatidylinositol Phosphate Metabolism (2)
SMP0000463
map00562
Phospholipid Biosynthesis (2)
SMP0000025
map00564
Phytanic Acid Peroxisomal Oxidation (6)
SMP0000450
-
Plasmalogen Synthesis (4)
SMP0000479
-
Porphyrin Metabolism (4)
SMP0000024
map00860
Propanoate Metabolism (10)
SMP0000016
map00640
Pterine Biosynthesis (1)
SMP0000005
map00790
Purine Metabolism (22)
SMP0000050
map00230
Pyrimidine Metabolism (18)
SMP0000046
map00240
Pyruvaldehyde Degradation (4)
SMP0000459
-
Pyruvate Metabolism (12)
SMP0000060
map00620
Retinol Metabolism (2)
SMP0000074
map00830
Riboflavin Metabolism (4)
SMP0000070
map00740
Selenoamino Acid Metabolism (5)
SMP0000029
map00450
Spermidine and Spermine Biosynthesis (4)
SMP0000445
-
Sphingolipid Metabolism (5)
SMP0000034
map00600
Starch and Sucrose Metabolism (9)
SMP0000058
map00500
Steroid Biosynthesis (5)
SMP0000023
map00100
Sulfate/Sulfite Metabolism (1)
SMP0000041
map00920
Taurine and Hypotaurine Metabolism (3)
SMP0000021
map00430
Thiamine Metabolism (3)
SMP0000076
map00730
Threonine and 2-Oxobutanoate Degradation (6)
SMP0000452
-
Thyroid Hormone Synthesis (2)
SMP0000716
-
Transfer of Acetyl Groups into Mitochondria (5)
SMP0000466
-
Trehalose Degradation (1)
SMP0000467
-
Tryptophan Metabolism (11)
SMP0000063
map00380
Tyrosine Metabolism (8)
SMP0000006
map00350
Ubiquinone Biosynthesis (1)
SMP0000065
map00130
Urea Cycle (10)
SMP0000059
map00330
Valine, Leucine and Isoleucine Degradation (14)
SMP0000032
map00280
Vitamin B6 Metabolism (6)
SMP0000017
map00750
Vitamin K Metabolism (1)
SMP0000464
-
Warburg Effect (23)
SMP0000654
-
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