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List of human metabolic pathways and metabolites (REACTOME)
Pathway name (# of metabolites detected in study)
Reactome pathway
Abnormal metabolism in phenylketonuria
REACT_121117
alpha-linolenic acid (ALA) metabolism
REACT_121147
Beta oxidation of butanoyl-CoA to acetyl-CoA
REACT_419
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
REACT_1708
Beta oxidation of hexanoyl-CoA to butanoyl-CoA
REACT_1887
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
REACT_735
Beta oxidation of myristoyl-CoA to lauroyl-CoA
REACT_2108
Beta oxidation of octanoyl-CoA to hexanoyl-CoA
REACT_1697
Beta oxidation of palmitoyl-CoA to myristoyl-CoA
REACT_2025
Beta-oxidation of pristanoyl-CoA
REACT_17017
Beta-oxidation of very long chain fatty acids
REACT_17062
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB
REACT_416
Branched-chain amino acid catabolism
REACT_197
Cell redox homeostasis
REACT_121394
Cholesterol biosynthesis
REACT_9405
Citric acid cycle (TCA cycle)
REACT_1785
Cobalamin (Cbl, vitamin B12) transport and metabolism
REACT_163862
Cytosolic iron-sulfur cluster assembly
REACT_160176
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
REACT_169149
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
REACT_169439
Detoxification of Reactive Oxygen Species
REACT_172715
Electron transport from NADPH to Ferredoxin
REACT_150128
eNOS activation
REACT_12477
Enzymatic degradation of dopamine by COMT
REACT_15548
Enzymatic degradation of Dopamine by monoamine oxidase
REACT_15511
Fatty acid, triacylglycerol, and ketone body metabolism
REACT_22279
FMO oxidises nucleophiles
REACT_13653
Glyoxylate metabolism
REACT_16925
Heme biosynthesis
REACT_9465
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
REACT_25367
Interconversion of polyamines
REACT_14805
Lysine catabolism
REACT_1298
Metabolism of serotonin
REACT_15532
Methylation
REACT_6946
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
REACT_160
Norepinephrine Neurotransmitter Release Cycle
REACT_15418
NOSIP mediated eNOS trafficking
REACT_12510
NOSTRIN mediated eNOS trafficking
REACT_12541
PAOs oxidise polyamines to amines
REACT_505
Phagosomal maturation (early endosomal stage)
REACT_121256
Plasmalogen biosynthesis
REACT_1407
Proline catabolism
REACT_1002
Purine catabolism
REACT_2086
Pyrimidine catabolism
REACT_1023
Pyruvate metabolism
REACT_2071
Regulation of pyruvate dehydrogenase (PDH) complex
REACT_12528
Respiratory electron transport
REACT_22393
Sulfide oxidation to sulfate
REACT_116010
Sulfur amino acid metabolism
REACT_115639
Synthesis and interconversion of nucleotide di- and triphosphates
REACT_21330
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
REACT_11041
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
REACT_111176
Ubiquinol biosynthesis
REACT_160111
VEGFA-VEGFR2 Pathway
REACT_228166
VEGFR2 mediated vascular permeability
REACT_228016
Vitamin B2 (riboflavin) metabolism
REACT_11070
Vitamin C (ascorbate) metabolism
REACT_11202
Vitamins B6 activation to pyridoxal phosphate
REACT_25012
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