List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Acetylcholine regulates insulin secretion REACT_18405
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers REACT_118700
Ca2+ pathway REACT_172761
DAG and IP3 signaling REACT_111064
Effects of PIP2 hydrolysis REACT_2202
Elevation of cytosolic Ca2+ levels REACT_162
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion REACT_19193
FCERI mediated Ca+2 mobilization REACT_163834
G alpha (q) signalling events REACT_18283
G beta:gamma signalling through PLC beta REACT_19145
Generation of second messenger molecules REACT_12623
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion REACT_18274
GPVI-mediated activation cascade REACT_1695
IP3 and IP4 transport between cytosol and nucleus REACT_150354
IPs transport between ER lumen and cytosol REACT_150405
PLC beta mediated events REACT_15426
Regulation of insulin secretion REACT_18325
Role of phospholipids in phagocytosis REACT_160158
Role of second messengers in netrin-1 signaling REACT_22228
Synthesis of IP2, IP, and Ins in the cytosol REACT_150352
Synthesis of IP3 and IP4 in the cytosol REACT_150312
Synthesis of IPs in the ER lumen REACT_150253
Synthesis of IPs in the nucleus REACT_150275
VEGFR2 mediated cell proliferation REACT_228024
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