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ST000004 Lipidomics studies on NIDDK / NIST human plasma samplesList of human metabolic pathways and metabolites (REACTOME)
Pathway name (# of metabolites detected in study)
Reactome pathway
ABCA transporters in lipid homeostasis (1)
REACT_111158
Activation of gene expression by SREBF (SREBP) (5)
REACT_147904
alpha-linolenic acid (ALA) metabolism (2)
REACT_121147
Arachidonate production from DAG (1)
REACT_19308
Arachidonic acid metabolism (1)
REACT_147851
BMAL1:CLOCK,NPAS2 activates circadian gene expression (5)
REACT_111118
Cell surface interactions at the vascular wall (1)
REACT_12051
Cholesterol biosynthesis (3)
REACT_9405
Chylomicron-mediated lipid transport (1)
REACT_6841
Circadian Clock (5)
REACT_24941
COX reactions (1)
REACT_1396
Cytosolic sulfonation of small molecules (1)
REACT_6913
Digestion of dietary lipid (2)
REACT_9518
Eicosanoids (2)
REACT_13645
Endogenous sterols (5)
REACT_13812
eNOS activation (1)
REACT_12477
Fatty acids (5)
REACT_13814
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (4)
REACT_19193
Fatty Acyl-CoA Biosynthesis (1)
REACT_1319
Free fatty acid receptors (12)
REACT_21268
G alpha (i) signalling events (5)
REACT_19231
G alpha (q) signalling events (9)
REACT_18283
G alpha (s) signalling events (2)
REACT_19327
Glycosphingolipid metabolism (1)
REACT_116105
HDL-mediated lipid transport (1)
REACT_13621
Hedgehog ligand biogenesis (1)
REACT_228111
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis (1)
REACT_494
LDL-mediated lipid transport (1)
REACT_6934
Leukotriene receptors (3)
REACT_18302
Linoleic acid (LA) metabolism (1)
REACT_121100
Lysosphingolipid and LPA receptors (1)
REACT_18365
Miscellaneous substrates (1)
REACT_13425
Orphan transporters (8)
REACT_267716
phospho-PLA2 pathway (1)
REACT_15466
Plasmalogen biosynthesis (1)
REACT_1407
Platelet sensitization by LDL (1)
REACT_23879
PPARA activates gene expression (6)
REACT_116145
Pregnenolone biosynthesis (1)
REACT_11038
Prostanoid ligand receptors (3)
REACT_18425
Pyrimidine biosynthesis (1)
REACT_21376
Regulation of cholesterol biosynthesis by SREBP (SREBF) (1)
REACT_147797
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (5)
REACT_19241
Respiratory electron transport (1)
REACT_22393
Retinoid cycle disease events (1)
REACT_160130
Retinoid metabolism and transport (4)
REACT_24968
REV-ERBA represses gene expression (5)
REACT_118789
Role of phospholipids in phagocytosis (1)
REACT_160158
RORA activates circadian gene expression (5)
REACT_118659
Scavenging by Class A Receptors (2)
REACT_163699
Scavenging by Class B Receptors (2)
REACT_163679
Scavenging by Class F Receptors (2)
REACT_163813
Scavenging by Class H Receptors (1)
REACT_164002
Scavenging of heme from plasma (1)
REACT_160163
Sphingolipid de novo biosynthesis (4)
REACT_115810
Sulfide oxidation to sulfate (1)
REACT_116010
Synthesis of 12-eicosatetraenoic acid derivatives (1)
REACT_150201
Synthesis of 15-eicosatetraenoic acid derivatives (2)
REACT_150422
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (4)
REACT_150134
Synthesis of 5-eicosatetraenoic acids (1)
REACT_150209
Synthesis of bile acids and bile salts (2)
REACT_11054
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (2)
REACT_11053
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (1)
REACT_11048
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (2)
REACT_11041
Synthesis of Dolichyl-phosphate (1)
REACT_22230
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) (7)
REACT_150417
Synthesis of Hepoxilins (HX) and Trioxilins (TrX) (1)
REACT_150292
Synthesis of Leukotrienes (LT) and Eoxins (EX) (7)
REACT_150420
Synthesis of Lipoxins (LX) (1)
REACT_150320
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (11)
REACT_150149
Synthesis of very long-chain fatty acyl-CoAs (2)
REACT_380
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (12)
REACT_24019
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (4)
REACT_23824
The canonical retinoid cycle in rods (twilight vision) (3)
REACT_160156
The retinoid cycle in cones (daylight vision) (1)
REACT_160083
Trafficking of dietary sterols (1)
REACT_13781
Transcriptional activation of mitochondrial biogenesis (5)
REACT_200608
Transcriptional regulation of white adipocyte differentiation (6)
REACT_27161
Transport of fatty acids (7)
REACT_23892
Transport of organic anions (3)
REACT_23988
VEGFR2 mediated cell proliferation (2)
REACT_228024
Vitamin D (calciferol) metabolism (1)
REACT_13523
YAP1- and WWTR1 (TAZ)-stimulated gene expression (5)
REACT_118713
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