ST000142 H1299 13C-labeled Cell Study
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
ABC-family proteins mediated transport (1) REACT_15480
ABH2 mediated Reversal of Alkylation Damage (2) REACT_526
ABH3 mediated Reversal of Alkylation Damage (2) REACT_1662
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate (1) REACT_160183
Abnormal metabolism in phenylketonuria (4) REACT_121117
Aflatoxin activation and detoxification (1) REACT_228214
Alpha-oxidation of phytanate (2) REACT_17003
Amino acid synthesis and interconversion (transamination) (4) REACT_238
Androgen biosynthesis (1) REACT_11059
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (3) REACT_416
Biosynthesis of A2E, implicated in retinal degradation (1) REACT_160194
Branched-chain amino acid catabolism (1) REACT_197
Carnitine synthesis (2) REACT_2125
Citric acid cycle (TCA cycle) (2) REACT_1785
Class A/1 (Rhodopsin-like receptors) (1) REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (2) REACT_18319
Collagen biosynthesis and modifying enzymes (1) REACT_121139
Condensation of Prophase Chromosomes (1) REACT_172744
Constitutive PI3K/AKT Signaling in Cancer (1) REACT_147727
CYP2E1 reactions (1) REACT_13797
Cysteine formation from homocysteine (1) REACT_115589
Cytosolic sulfonation of small molecules (1) REACT_6913
Degradation of cysteine and homocysteine (1) REACT_115654
Degradation of GABA (2) REACT_23964
Endogenous sterols (3) REACT_13812
Ethanol oxidation (1) REACT_34
Fatty Acyl-CoA Biosynthesis (1) REACT_1319
Fructose catabolism (2) REACT_1571
GABA synthesis (1) REACT_24020
G alpha (i) signalling events (3) REACT_19231
Glucocorticoid biosynthesis (2) REACT_11036
Gluconeogenesis (5) REACT_1520
Glycolysis (2) REACT_1383
Glyoxylate metabolism (1) REACT_16925
HDMs demethylate histones (1) REACT_228178
Histidine catabolism (1) REACT_1249
Inactivation, recovery and regulation of the phototransduction cascade (1) REACT_163919
Insulin effects increased synthesis of Xylulose-5-Phosphate (1) REACT_939
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (1) REACT_25367
Lysine catabolism (2) REACT_1298
Metabolism of serotonin (1) REACT_15532
Methionine salvage pathway (1) REACT_75881
Mineralocorticoid biosynthesis (1) REACT_11047
Mitochondrial iron-sulfur cluster biogenesis (1) REACT_150353
Molybdenum cofactor biosynthesis (1) REACT_25073
NADPH regeneration (1) REACT_16904
Organic anion transport (2) REACT_22310
Organic anion transporters (1) REACT_19372
Oxidative Stress Induced Senescence (1) REACT_169436
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_121226
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_120916
Pentose phosphate pathway (hexose monophosphate shunt) (1) REACT_1859
Phenylalanine and tyrosine catabolism (2) REACT_1786
Pregnenolone biosynthesis (1) REACT_11038
Proton-coupled monocarboxylate transport (2) REACT_20515
Pyrimidine catabolism (1) REACT_1023
Pyruvate metabolism (1) REACT_2071
Regulation of ornithine decarboxylase (ODC) (1) REACT_13565
Regulation of pyruvate dehydrogenase (PDH) complex (1) REACT_12528
Retinoid cycle disease events (1) REACT_160130
Retinoid metabolism and transport (1) REACT_24968
Serine biosynthesis (3) REACT_115789
Sialic acid metabolism (1) REACT_200874
Signaling by constitutively active EGFR (2) REACT_115852
Sphingolipid de novo biosynthesis (2) REACT_115810
Sterols are 12-hydroxylated by CYP8B1 (1) REACT_13438
Synthesis of 15-eicosatetraenoic acid derivatives (1) REACT_150422
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (2) REACT_11041
Synthesis of Ketone Bodies (1) REACT_1464
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (4) REACT_150149
TET1,2,3 and TDG demethylate DNA (1) REACT_200682
The canonical retinoid cycle in rods (twilight vision) (1) REACT_160156
The retinoid cycle in cones (daylight vision) (1) REACT_160083
Transport of organic anions (1) REACT_23988
Tryptophan catabolism (6) REACT_916
Utilization of Ketone Bodies (1) REACT_59
Vitamins B6 activation to pyridoxal phosphate (2) REACT_25012
Xenobiotics (1) REACT_13543
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