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ST000241 Cyclobutene- and cyclobutane-functionalized fatty acids as novel biochemical probes of structure and function in HepG2 cellsList of human metabolic pathways and metabolites (REACTOME)
Pathway name (# of metabolites detected in study)
Reactome pathway
Abacavir metabolism (1)
REACT_121388
ABC-family proteins mediated transport (1)
REACT_15480
Activation of gene expression by SREBF (SREBP) (1)
REACT_147904
Adenosine P1 receptors (1)
REACT_18288
Biosynthesis of A2E, implicated in retinal degradation (1)
REACT_160194
BMAL1:CLOCK,NPAS2 activates circadian gene expression (1)
REACT_111118
Cholesterol biosynthesis (1)
REACT_9405
Circadian Clock (1)
REACT_24941
Cytosolic sulfonation of small molecules (1)
REACT_6913
Digestion of dietary lipid (2)
REACT_9518
Endogenous sterols (1)
REACT_13812
eNOS activation (1)
REACT_12477
Factors involved in megakaryocyte development and platelet production (1)
REACT_24970
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (2)
REACT_19193
Fatty Acyl-CoA Biosynthesis (1)
REACT_1319
Free fatty acid receptors (4)
REACT_21268
G alpha (i) signalling events (1)
REACT_19231
G alpha (q) signalling events (3)
REACT_18283
G alpha (s) signalling events (1)
REACT_19327
Gluconeogenesis (1)
REACT_1520
Glutathione synthesis and recycling (1)
REACT_6960
Glycolysis (1)
REACT_1383
Heme biosynthesis (1)
REACT_9465
Import of palmitoyl-CoA into the mitochondrial matrix (1)
REACT_11082
Inactivation, recovery and regulation of the phototransduction cascade (1)
REACT_163919
IPs transport between cytosol and ER lumen (1)
REACT_150204
IPs transport between ER lumen and cytosol (1)
REACT_150405
IPs transport between ER lumen and nucleus (1)
REACT_150164
IPs transport between nucleus and cytosol (1)
REACT_150458
Metabolism of folate and pterines (1)
REACT_11167
Metabolism of polyamines (1)
REACT_14820
Methylation (1)
REACT_6946
Miscellaneous substrates (1)
REACT_13425
NGF-independant TRKA activation (1)
REACT_11046
Orphan transporters (2)
REACT_267716
Plasmalogen biosynthesis (1)
REACT_1407
PPARA activates gene expression (1)
REACT_116145
Prostanoid ligand receptors (1)
REACT_18425
Purine catabolism (1)
REACT_2086
Purine salvage (1)
REACT_1923
Pyrimidine biosynthesis (1)
REACT_21376
Pyrimidine catabolism (1)
REACT_1023
Recycling of bile acids and salts (1)
REACT_11042
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (1)
REACT_19241
Regulation of pyruvate dehydrogenase (PDH) complex (1)
REACT_12528
Retinoid cycle disease events (2)
REACT_160130
Retinoid metabolism and transport (3)
REACT_24968
REV-ERBA represses gene expression (1)
REACT_118789
RORA activates circadian gene expression (1)
REACT_118659
Scavenging by Class A Receptors (1)
REACT_163699
Scavenging by Class B Receptors (1)
REACT_163679
Scavenging by Class F Receptors (1)
REACT_163813
Serine biosynthesis (1)
REACT_115789
Sphingolipid de novo biosynthesis (1)
REACT_115810
Sulfur amino acid metabolism (2)
REACT_115639
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (1)
REACT_11053
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (1)
REACT_11041
Synthesis of IPs in the ER lumen (1)
REACT_150253
Synthesis of IPs in the nucleus (1)
REACT_150275
Synthesis of Leukotrienes (LT) and Eoxins (EX) (1)
REACT_150420
Synthesis of Lipoxins (LX) (1)
REACT_150320
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (1)
REACT_150149
Synthesis of pyrophosphates in the cytosol (1)
REACT_150188
Synthesis of very long-chain fatty acyl-CoAs (1)
REACT_380
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (4)
REACT_24019
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (2)
REACT_23824
The canonical retinoid cycle in rods (twilight vision) (3)
REACT_160156
The retinoid cycle in cones (daylight vision) (2)
REACT_160083
Thyroxine biosynthesis (1)
REACT_15292
Transcriptional activation of mitochondrial biogenesis (1)
REACT_200608
Transcriptional regulation of white adipocyte differentiation (1)
REACT_27161
Transport of fatty acids (3)
REACT_23892
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (1)
REACT_1206
Transport of organic anions (2)
REACT_23988
Vitamin D (calciferol) metabolism (1)
REACT_13523
Vitamins (1)
REACT_13450
YAP1- and WWTR1 (TAZ)-stimulated gene expression (1)
REACT_118713
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