ST000567 Large Scale HILIC Profiling of the Effects of Curcumin Supplementation of Older Adults: Relation to Vascular Function
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Abnormal metabolism in phenylketonuria (1) REACT_121117
Acetylation (2) REACT_6732
Activation of gene expression by SREBF (SREBP) (1) REACT_147904
Amino acid synthesis and interconversion (transamination) (2) REACT_238
Amino acid transport across the plasma membrane (6) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (6) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (6) REACT_75842
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (2) REACT_13721
BMAL1:CLOCK,NPAS2 activates circadian gene expression (1) REACT_111118
Branched-chain amino acid catabolism (2) REACT_197
Circadian Clock (1) REACT_24941
Class A/1 (Rhodopsin-like receptors) (1) REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (1) REACT_18319
Cobalamin (Cbl, vitamin B12) transport and metabolism (1) REACT_163862
Conjugation of benzoate with glycine (1) REACT_6933
Conjugation of phenylacetate with glutamine (1) REACT_6800
Creatine metabolism (1) REACT_813
Cross-presentation of soluble exogenous antigens (endosomes) (6) REACT_111056
Cytosolic sulfonation of small molecules (2) REACT_6913
Cytosolic tRNA aminoacylation (6) REACT_15306
Endogenous sterols (1) REACT_13812
Endosomal/Vacuolar pathway (6) REACT_111168
ER-Phagosome pathway (6) REACT_111178
G alpha (i) signalling events (3) REACT_19231
Glucuronidation (1) REACT_6784
Glutathione synthesis and recycling (6) REACT_6960
Glycosphingolipid metabolism (1) REACT_116105
Glyoxylate metabolism (1) REACT_16925
Heme degradation (1) REACT_22297
Hydroxycarboxylic acid-binding receptors (2) REACT_163785
Inactivation, recovery and regulation of the phototransduction cascade (1) REACT_163919
Interconversion of polyamines (1) REACT_14805
Linoleic acid (LA) metabolism (1) REACT_121100
Methionine salvage pathway (1) REACT_75881
Methylation (1) REACT_6946
Miscellaneous substrates (1) REACT_13425
Mitochondrial iron-sulfur cluster biogenesis (1) REACT_150353
Mitochondrial tRNA aminoacylation (6) REACT_15302
Molybdenum cofactor biosynthesis (2) REACT_25073
Na+/Cl- dependent neurotransmitter transporters (6) REACT_20506
Organic anion transport (1) REACT_22310
Organic anion transporters (1) REACT_19372
Organic cation transport (1) REACT_22357
Orphan transporters (2) REACT_267716
PAOs oxidise polyamines to amines (1) REACT_505
Phenylalanine and tyrosine catabolism (2) REACT_1786
PPARA activates gene expression (1) REACT_116145
Proline catabolism (1) REACT_1002
Proton-coupled monocarboxylate transport (1) REACT_20515
Proton-coupled neutral amino acid transporters (2) REACT_19348
Proton/oligonucleotide cotransporters (6) REACT_19328
Pyrimidine biosynthesis (1) REACT_21376
Pyrimidine catabolism (2) REACT_1023
Pyrimidine salvage reactions (1) REACT_655
Pyruvate metabolism (1) REACT_2071
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (1) REACT_19241
Respiratory electron transport (1) REACT_22393
Retinoid metabolism and transport (1) REACT_24968
REV-ERBA represses gene expression (1) REACT_118789
RORA activates circadian gene expression (1) REACT_118659
Serotonin and melatonin biosynthesis (1) REACT_15439
Sphingolipid de novo biosynthesis (1) REACT_115810
Sulfide oxidation to sulfate (1) REACT_116010
Sulfur amino acid metabolism (1) REACT_115639
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (1) REACT_11048
Synthesis of Ketone Bodies (1) REACT_1464
The canonical retinoid cycle in rods (twilight vision) (1) REACT_160156
Thyroxine biosynthesis (1) REACT_15292
Transcriptional activation of mitochondrial biogenesis (1) REACT_200608
Transcriptional regulation of white adipocyte differentiation (1) REACT_27161
Transport of fatty acids (1) REACT_23892
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (1) REACT_19305
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (1) REACT_1206
Tryptophan catabolism (2) REACT_916
Utilization of Ketone Bodies (1) REACT_59
VEGFR2 mediated cell proliferation (1) REACT_228024
YAP1- and WWTR1 (TAZ)-stimulated gene expression (1) REACT_118713
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