ST000691 Metabolomics of diabetic nephropathy
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Abnormal metabolism in phenylketonuria (2) REACT_121117
Activation of gene expression by SREBF (SREBP) (1) REACT_147904
alpha-linolenic acid (ALA) metabolism (1) REACT_121147
Amino acid synthesis and interconversion (transamination) (1) REACT_238
Amino acid transport across the plasma membrane (6) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (6) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (6) REACT_75842
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (1) REACT_13721
BMAL1:CLOCK,NPAS2 activates circadian gene expression (1) REACT_111118
Branched-chain amino acid catabolism (2) REACT_197
Carnitine synthesis (1) REACT_2125
Catecholamine biosynthesis (1) REACT_15551
Circadian Clock (1) REACT_24941
Citric acid cycle (TCA cycle) (1) REACT_1785
Class A/1 (Rhodopsin-like receptors) (2) REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (1) REACT_18319
Class II GLUTs (1) REACT_19281
Cobalamin (Cbl, vitamin B12) transport and metabolism (1) REACT_163862
Conjugation of benzoate with glycine (1) REACT_6933
Creatine metabolism (1) REACT_813
Cross-presentation of soluble exogenous antigens (endosomes) (6) REACT_111056
Cytosolic tRNA aminoacylation (6) REACT_15306
Degradation of cysteine and homocysteine (1) REACT_115654
Digestion of dietary lipid (1) REACT_9518
Endogenous sterols (1) REACT_13812
Endosomal/Vacuolar pathway (6) REACT_111168
ER-Phagosome pathway (6) REACT_111178
Fatty Acyl-CoA Biosynthesis (1) REACT_1319
Free fatty acid receptors (5) REACT_21268
G alpha (i) signalling events (1) REACT_19231
G alpha (s) signalling events (2) REACT_19327
Glucocorticoid biosynthesis (1) REACT_11036
Gluconeogenesis (1) REACT_1520
Glutathione synthesis and recycling (6) REACT_6960
Glycolysis (1) REACT_1383
Glyoxylate metabolism (1) REACT_16925
Import of palmitoyl-CoA into the mitochondrial matrix (1) REACT_11082
Inactivation, recovery and regulation of the phototransduction cascade (1) REACT_163919
Linoleic acid (LA) metabolism (1) REACT_121100
Methionine salvage pathway (1) REACT_75881
Methylation (1) REACT_6946
Miscellaneous substrates (1) REACT_13425
Mitochondrial tRNA aminoacylation (6) REACT_15302
Molybdenum cofactor biosynthesis (1) REACT_25073
Na+/Cl- dependent neurotransmitter transporters (6) REACT_20506
Organic anion transport (1) REACT_22310
Orphan transporters (3) REACT_267716
Phenylalanine and tyrosine catabolism (1) REACT_1786
PPARA activates gene expression (2) REACT_116145
Proline catabolism (1) REACT_1002
Proton-coupled neutral amino acid transporters (1) REACT_19348
Proton/oligonucleotide cotransporters (6) REACT_19328
Purine catabolism (2) REACT_2086
Pyrimidine biosynthesis (1) REACT_21376
Pyrimidine catabolism (2) REACT_1023
Pyrimidine salvage reactions (2) REACT_655
Recycling of bile acids and salts (2) REACT_11042
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (1) REACT_19241
Regulation of pyruvate dehydrogenase (PDH) complex (1) REACT_12528
Retinoid metabolism and transport (1) REACT_24968
REV-ERBA represses gene expression (1) REACT_118789
RORA activates circadian gene expression (1) REACT_118659
Serotonin and melatonin biosynthesis (1) REACT_15439
Sodium-coupled sulphate, di- and tri-carboxylate transporters (1) REACT_20646
Stimuli-sensing channels (1) REACT_160189
Sulfur amino acid metabolism (1) REACT_115639
Synthesis and interconversion of nucleotide di- and triphosphates (1) REACT_21330
Synthesis of bile acids and bile salts (1) REACT_11054
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (1) REACT_11048
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (2) REACT_11041
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (5) REACT_24019
The canonical retinoid cycle in rods (twilight vision) (1) REACT_160156
Thyroxine biosynthesis (1) REACT_15292
Transcriptional activation of mitochondrial biogenesis (1) REACT_200608
Transcriptional regulation of white adipocyte differentiation (1) REACT_27161
Transport of fatty acids (2) REACT_23892
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (1) REACT_1206
Transport of organic anions (1) REACT_23988
Tryptophan catabolism (2) REACT_916
Vitamins (1) REACT_13450
YAP1- and WWTR1 (TAZ)-stimulated gene expression (1) REACT_118713
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