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ST000701 Differences in metabolism in mouse embryonic fibroblasts (control vs SCF-beta-TrCP knockout)List of human metabolic pathways and metabolites (REACTOME)
Pathway name (# of metabolites detected in study)
Reactome pathway
ABH2 mediated Reversal of Alkylation Damage (1)
REACT_526
ABH3 mediated Reversal of Alkylation Damage (1)
REACT_1662
Abnormal metabolism in phenylketonuria (4)
REACT_121117
Alpha-oxidation of phytanate (1)
REACT_17003
Amino acid synthesis and interconversion (transamination) (5)
REACT_238
Amino acid transport across the plasma membrane (11)
REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (12)
REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (12)
REACT_75842
Astrocytic Glutamate-Glutamine Uptake And Metabolism (1)
REACT_13639
Biotin transport and metabolism (1)
REACT_11153
Branched-chain amino acid catabolism (3)
REACT_197
Carnitine synthesis (1)
REACT_2125
Catecholamine biosynthesis (1)
REACT_15551
Citric acid cycle (TCA cycle) (3)
REACT_1785
Class A/1 (Rhodopsin-like receptors) (1)
REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (1)
REACT_18319
Class II GLUTs (1)
REACT_19281
Cleavage of the damaged purine (1)
REACT_1729
Cobalamin (Cbl, vitamin B12) transport and metabolism (1)
REACT_163862
Collagen biosynthesis and modifying enzymes (1)
REACT_121139
Condensation of Prophase Chromosomes (1)
REACT_172744
Conjugation of benzoate with glycine (1)
REACT_6933
Conjugation of phenylacetate with glutamine (1)
REACT_6800
Creatine metabolism (1)
REACT_813
Cross-presentation of soluble exogenous antigens (endosomes) (12)
REACT_111056
Cysteine formation from homocysteine (1)
REACT_115589
Cytosolic tRNA aminoacylation (12)
REACT_15306
degradation of AXIN (1)
REACT_200766
Degradation of cysteine and homocysteine (1)
REACT_115654
Degradation of GABA (1)
REACT_23964
Downregulation of SMAD2/3:SMAD4 transcriptional activity (1)
REACT_121111
Endosomal/Vacuolar pathway (12)
REACT_111168
ER-Phagosome pathway (12)
REACT_111178
Fatty Acyl-CoA Biosynthesis (2)
REACT_1319
Free fatty acid receptors (1)
REACT_21268
Fructose catabolism (1)
REACT_1571
G alpha (i) signalling events (2)
REACT_19231
G alpha (q) signalling events (2)
REACT_18283
G alpha (s) signalling events (1)
REACT_19327
Glucocorticoid biosynthesis (1)
REACT_11036
Gluconeogenesis (4)
REACT_1520
Glutamate Neurotransmitter Release Cycle (1)
REACT_12591
Glutathione synthesis and recycling (13)
REACT_6960
Glycolysis (2)
REACT_1383
Glyoxylate metabolism (1)
REACT_16925
HDMs demethylate histones (1)
REACT_228178
Histamine receptors (1)
REACT_16903
Histidine catabolism (3)
REACT_1249
HS-GAG degradation (1)
REACT_120752
Inactivation, recovery and regulation of the phototransduction cascade (1)
REACT_163919
Lysine catabolism (1)
REACT_1298
Metabolism of folate and pterines (1)
REACT_11167
Metabolism of serotonin (1)
REACT_15532
Methionine salvage pathway (1)
REACT_75881
Methylation (1)
REACT_6946
Mitochondrial tRNA aminoacylation (12)
REACT_15302
Molybdenum cofactor biosynthesis (1)
REACT_25073
Na+/Cl- dependent neurotransmitter transporters (12)
REACT_20506
Nicotinamide salvaging (1)
REACT_11213
Nicotinate metabolism (1)
REACT_11088
Organic anion transport (1)
REACT_22310
Organic anion transporters (2)
REACT_19372
Organic cation transport (1)
REACT_22357
Oxidative Stress Induced Senescence (1)
REACT_169436
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha (1)
REACT_121226
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (1)
REACT_120916
Phenylalanine and tyrosine catabolism (2)
REACT_1786
Proline catabolism (1)
REACT_1002
Proton-coupled monocarboxylate transport (1)
REACT_20515
Proton-coupled neutral amino acid transporters (1)
REACT_19348
Proton/oligonucleotide cotransporters (12)
REACT_19328
Purine catabolism (3)
REACT_2086
Purine ribonucleoside monophosphate biosynthesis (2)
REACT_1776
Purine salvage (2)
REACT_1923
Pyrimidine biosynthesis (2)
REACT_21376
Pyrimidine catabolism (5)
REACT_1023
Pyrimidine salvage reactions (4)
REACT_655
Pyruvate metabolism (1)
REACT_2071
Regulation of HSF1-mediated heat shock response (1)
REACT_200780
Regulation of pyruvate dehydrogenase (PDH) complex (1)
REACT_12528
Serotonin and melatonin biosynthesis (2)
REACT_15439
Sialic acid metabolism (1)
REACT_200874
SIRT1 negatively regulates rRNA Expression (1)
REACT_200827
Sodium-coupled sulphate, di- and tri-carboxylate transporters (2)
REACT_20646
Stimuli-sensing channels (1)
REACT_160189
Sulfide oxidation to sulfate (1)
REACT_116010
Sulfur amino acid metabolism (1)
REACT_115639
Synthesis and interconversion of nucleotide di- and triphosphates (1)
REACT_21330
Synthesis of UDP-N-acetyl-glucosamine (1)
REACT_22394
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (1)
REACT_24019
TET1,2,3 and TDG demethylate DNA (1)
REACT_200682
Thyroxine biosynthesis (1)
REACT_15292
Transport of inorganic cations/anions and amino acids/oligopeptides (1)
REACT_19397
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (5)
REACT_1206
Tryptophan catabolism (3)
REACT_916
Urea cycle (2)
REACT_847
Utilization of Ketone Bodies (1)
REACT_59
Vitamin B2 (riboflavin) metabolism (1)
REACT_11070
Vitamins B6 activation to pyridoxal phosphate (1)
REACT_25012
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