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ST001375 Fructosamine-3-kinase (FN3K) KO in HepG2 liver cancer cellsList of human metabolic pathways and metabolites (REACTOME)
Pathway name (# of metabolites detected in study)
Reactome pathway
Abnormal metabolism in phenylketonuria (2)
REACT_121117
Activation of AMPA receptors (1)
REACT_18338
Activation of Ca-permeable Kainate Receptor (1)
REACT_21346
Activation of Na-permeable Kainate Receptors (1)
REACT_21343
Acyl chain remodeling of DAG and TAG (1)
REACT_121122
Aflatoxin activation and detoxification (3)
REACT_228214
Agmatine biosynthesis (1)
REACT_14800
Amino acid synthesis and interconversion (transamination) (5)
REACT_238
Amino acid transport across the plasma membrane (10)
REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (11)
REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (11)
REACT_75842
Arachidonate production from DAG (1)
REACT_19308
Astrocytic Glutamate-Glutamine Uptake And Metabolism (2)
REACT_13639
Biotin transport and metabolism (1)
REACT_11153
Branched-chain amino acid catabolism (3)
REACT_197
Carnitine synthesis (1)
REACT_2125
Citric acid cycle (TCA cycle) (1)
REACT_1785
Class C/3 (Metabotropic glutamate/pheromone receptors) (2)
REACT_18319
Conjugation of benzoate with glycine (1)
REACT_6933
Conjugation of phenylacetate with glutamine (1)
REACT_6800
Conjugation of salicylate with glycine (1)
REACT_6812
Creatine metabolism (3)
REACT_813
CREB phosphorylation through the activation of CaMKII (2)
REACT_20642
Cross-presentation of soluble exogenous antigens (endosomes) (11)
REACT_111056
Cysteine formation from homocysteine (1)
REACT_115589
Cytosolic tRNA aminoacylation (11)
REACT_15306
Degradation of cysteine and homocysteine (1)
REACT_115654
Degradation of GABA (1)
REACT_23964
Detoxification of Reactive Oxygen Species (1)
REACT_172715
Endosomal/Vacuolar pathway (11)
REACT_111168
EPHB-mediated forward signaling (2)
REACT_228085
ER-Phagosome pathway (11)
REACT_111178
Fatty Acyl-CoA Biosynthesis (1)
REACT_1319
GABA synthesis (1)
REACT_24020
G alpha (i) signalling events (2)
REACT_19231
G alpha (q) signalling events (2)
REACT_18283
Gluconeogenesis (3)
REACT_1520
Glutamate Neurotransmitter Release Cycle (2)
REACT_12591
Glutathione conjugation (1)
REACT_6926
Glutathione synthesis and recycling (12)
REACT_6960
Glycolysis (1)
REACT_1383
Glyoxylate metabolism (2)
REACT_16925
Heme biosynthesis (1)
REACT_9465
Histidine catabolism (1)
REACT_1249
HS-GAG degradation (1)
REACT_120752
Hydroxycarboxylic acid-binding receptors (1)
REACT_163785
Interconversion of polyamines (1)
REACT_14805
Ligand-gated ion channel transport (1)
REACT_25387
Lysine catabolism (2)
REACT_1298
Metabolism of folate and pterines (3)
REACT_11167
Metabolism of polyamines (1)
REACT_14820
Mitochondrial iron-sulfur cluster biogenesis (1)
REACT_150353
Mitochondrial tRNA aminoacylation (11)
REACT_15302
Molybdenum cofactor biosynthesis (1)
REACT_25073
Na+/Cl- dependent neurotransmitter transporters (9)
REACT_20506
Nicotinate metabolism (2)
REACT_11088
Organic anion transport (1)
REACT_22310
Organic anion transporters (2)
REACT_19372
PAOs oxidise polyamines to amines (1)
REACT_505
Phagosomal maturation (early endosomal stage) (1)
REACT_121256
Phenylalanine and tyrosine catabolism (3)
REACT_1786
Presynaptic function of Kainate receptors (1)
REACT_21254
Proline catabolism (2)
REACT_1002
Proton-coupled monocarboxylate transport (1)
REACT_20515
Proton-coupled neutral amino acid transporters (3)
REACT_19348
Proton/oligonucleotide cotransporters (11)
REACT_19328
Purine catabolism (1)
REACT_2086
Purine ribonucleoside monophosphate biosynthesis (4)
REACT_1776
Pyrimidine biosynthesis (3)
REACT_21376
Pyrimidine catabolism (1)
REACT_1023
Pyruvate metabolism (1)
REACT_2071
Ras activation uopn Ca2+ infux through NMDA receptor (2)
REACT_20546
Recycling of bile acids and salts (1)
REACT_11042
Serine biosynthesis (2)
REACT_115789
Sodium-coupled sulphate, di- and tri-carboxylate transporters (1)
REACT_20646
Sphingolipid de novo biosynthesis (1)
REACT_115810
Sulfide oxidation to sulfate (1)
REACT_116010
Sulfur amino acid metabolism (2)
REACT_115639
Synthesis and interconversion of nucleotide di- and triphosphates (3)
REACT_21330
Synthesis of 12-eicosatetraenoic acid derivatives (1)
REACT_150201
Synthesis of 15-eicosatetraenoic acid derivatives (1)
REACT_150422
Synthesis of 5-eicosatetraenoic acids (1)
REACT_150209
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (1)
REACT_11041
Synthesis of Leukotrienes (LT) and Eoxins (EX) (3)
REACT_150420
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (1)
REACT_150149
Synthesis of PS (1)
REACT_120823
Synthesis of UDP-N-acetyl-glucosamine (2)
REACT_22394
Synthesis, secretion, and deacylation of Ghrelin (1)
REACT_19189
The fatty acid cycling model (1)
REACT_6258
Thyroxine biosynthesis (1)
REACT_15292
Transport of inorganic cations/anions and amino acids/oligopeptides (3)
REACT_19397
Tryptophan catabolism (2)
REACT_916
Unblocking of NMDA receptor, glutamate binding and activation (2)
REACT_20594
Urea cycle (2)
REACT_847
Vitamin C (ascorbate) metabolism (1)
REACT_11202
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