ST001432 A Compromised Developmental Trajectory of the Infant Gut Microbiome and Metabolome in Atopic Eczema - (untargeted global metabolomics profiling) )
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
ABCA transporters in lipid homeostasis (1) REACT_111158
ABH2 mediated Reversal of Alkylation Damage (1) REACT_526
ABH3 mediated Reversal of Alkylation Damage (1) REACT_1662
Abnormal metabolism in phenylketonuria (2) REACT_121117
Activation of gene expression by SREBF (SREBP) (2) REACT_147904
Aflatoxin activation and detoxification (2) REACT_228214
Alpha-oxidation of phytanate (1) REACT_17003
Amino acid synthesis and interconversion (transamination) (3) REACT_238
Amino acid transport across the plasma membrane (6) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (4) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (4) REACT_75842
Beta-oxidation of pristanoyl-CoA (1) REACT_17017
Beta-oxidation of very long chain fatty acids (1) REACT_17062
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (1) REACT_416
BMAL1:CLOCK,NPAS2 activates circadian gene expression (2) REACT_111118
Carnitine synthesis (2) REACT_2125
Catecholamine biosynthesis (1) REACT_15551
Cell surface interactions at the vascular wall (1) REACT_12051
Cholesterol biosynthesis (1) REACT_9405
Chylomicron-mediated lipid transport (1) REACT_6841
Circadian Clock (2) REACT_24941
Citric acid cycle (TCA cycle) (2) REACT_1785
Class A/1 (Rhodopsin-like receptors) (2) REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (1) REACT_18319
Collagen biosynthesis and modifying enzymes (1) REACT_121139
Condensation of Prophase Chromosomes (1) REACT_172744
Conjugation of benzoate with glycine (2) REACT_6933
Conjugation of salicylate with glycine (1) REACT_6812
Creatine metabolism (2) REACT_813
CREB phosphorylation through the activation of CaMKII (1) REACT_20642
Cross-presentation of soluble exogenous antigens (endosomes) (4) REACT_111056
Cytosolic sulfonation of small molecules (1) REACT_6913
Cytosolic tRNA aminoacylation (4) REACT_15306
Degradation of GABA (1) REACT_23964
Digestion of dietary lipid (2) REACT_9518
Endogenous sterols (1) REACT_13812
Endosomal/Vacuolar pathway (4) REACT_111168
eNOS activation (1) REACT_12477
EPHB-mediated forward signaling (1) REACT_228085
ER-Phagosome pathway (4) REACT_111178
ER Quality Control Compartment (ERQC) (1) REACT_25091
Ethanol oxidation (1) REACT_34
Fatty acids (1) REACT_13814
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (4) REACT_19193
Fatty Acyl-CoA Biosynthesis (1) REACT_1319
Free fatty acid receptors (9) REACT_21268
Fructose catabolism (1) REACT_1571
G alpha (i) signalling events (3) REACT_19231
G alpha (q) signalling events (8) REACT_18283
Glutathione synthesis and recycling (4) REACT_6960
Glyoxylate metabolism (2) REACT_16925
HDL-mediated lipid transport (1) REACT_13621
HDMs demethylate histones (1) REACT_228178
Hedgehog ligand biogenesis (1) REACT_228111
Heme biosynthesis (1) REACT_9465
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis (1) REACT_494
HS-GAG biosynthesis (1) REACT_121248
Hydroxycarboxylic acid-binding receptors (2) REACT_163785
Inositol transporters (1) REACT_19188
LDL-mediated lipid transport (1) REACT_6934
Ligand-gated ion channel transport (1) REACT_25387
Linoleic acid (LA) metabolism (1) REACT_121100
Metabolism of folate and pterines (1) REACT_11167
Metabolism of polyamines (1) REACT_14820
Mitochondrial iron-sulfur cluster biogenesis (1) REACT_150353
Mitochondrial tRNA aminoacylation (4) REACT_15302
Molybdenum cofactor biosynthesis (1) REACT_25073
Na+/Cl- dependent neurotransmitter transporters (5) REACT_20506
Na+-dependent glucose transporters (1) REACT_19165
Nicotinamide salvaging (1) REACT_11213
NoRC negatively regulates rRNA expression (1) REACT_200856
Organic anion transport (1) REACT_22310
Organic anion transporters (4) REACT_19372
Orphan transporters (3) REACT_267716
Oxidative Stress Induced Senescence (1) REACT_169436
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_121226
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_120916
Phenylalanine and tyrosine catabolism (2) REACT_1786
Plasmalogen biosynthesis (1) REACT_1407
Platelet sensitization by LDL (1) REACT_23879
PPARA activates gene expression (2) REACT_116145
Pregnenolone biosynthesis (1) REACT_11038
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 (1) REACT_25396
Proline catabolism (1) REACT_1002
Proton-coupled monocarboxylate transport (1) REACT_20515
Proton-coupled neutral amino acid transporters (3) REACT_19348
Proton/oligonucleotide cotransporters (4) REACT_19328
Purine ribonucleoside monophosphate biosynthesis (1) REACT_1776
Pyrimidine catabolism (2) REACT_1023
Pyruvate metabolism (1) REACT_2071
Ras activation uopn Ca2+ infux through NMDA receptor (1) REACT_20546
Reactions specific to the complex N-glycan synthesis pathway (1) REACT_25302
Recycling of bile acids and salts (1) REACT_11042
Regulation of cholesterol biosynthesis by SREBP (SREBF) (1) REACT_147797
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (2) REACT_19241
Retinoid cycle disease events (1) REACT_160130
Retinoid metabolism and transport (4) REACT_24968
Reuptake of GABA (1) REACT_23910
REV-ERBA represses gene expression (2) REACT_118789
RORA activates circadian gene expression (2) REACT_118659
Scavenging by Class A Receptors (3) REACT_163699
Scavenging by Class B Receptors (1) REACT_163679
Scavenging by Class F Receptors (1) REACT_163813
Scavenging by Class H Receptors (1) REACT_164002
Scavenging of heme from plasma (1) REACT_160163
Sodium-coupled sulphate, di- and tri-carboxylate transporters (1) REACT_20646
Sulfur amino acid metabolism (1) REACT_115639
Synthesis of bile acids and bile salts (1) REACT_11054
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (1) REACT_11053
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (1) REACT_11048
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (2) REACT_11041
Synthesis of glycosylphosphatidylinositol (GPI) (1) REACT_952
Synthesis of IP2, IP, and Ins in the cytosol (1) REACT_150352
Synthesis of Ketone Bodies (1) REACT_1464
Synthesis of Leukotrienes (LT) and Eoxins (EX) (1) REACT_150420
Synthesis of PI (1) REACT_121000
Synthesis of very long-chain fatty acyl-CoAs (1) REACT_380
Synthesis, secretion, and deacylation of Ghrelin (2) REACT_19189
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (6) REACT_24019
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (4) REACT_23824
TET1,2,3 and TDG demethylate DNA (1) REACT_200682
The canonical retinoid cycle in rods (twilight vision) (3) REACT_160156
The retinoid cycle in cones (daylight vision) (1) REACT_160083
Thyroxine biosynthesis (2) REACT_15292
Trafficking of dietary sterols (1) REACT_13781
Transcriptional activation of mitochondrial biogenesis (2) REACT_200608
Transcriptional regulation of white adipocyte differentiation (2) REACT_27161
Transport of fatty acids (6) REACT_23892
Transport of inorganic cations/anions and amino acids/oligopeptides (1) REACT_19397
Tryptophan catabolism (1) REACT_916
Unblocking of NMDA receptor, glutamate binding and activation (1) REACT_20594
Urea cycle (1) REACT_847
Utilization of Ketone Bodies (2) REACT_59
YAP1- and WWTR1 (TAZ)-stimulated gene expression (2) REACT_118713
  logo