ST001433 Evidence for proline utilisation by oral bacterial biofilms grown in saliva
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
ABH2 mediated Reversal of Alkylation Damage (1) REACT_526
ABH3 mediated Reversal of Alkylation Damage (1) REACT_1662
Abnormal metabolism in phenylketonuria (3) REACT_121117
Activation of AMPA receptors (1) REACT_18338
Activation of Ca-permeable Kainate Receptor (1) REACT_21346
Activation of Na-permeable Kainate Receptors (1) REACT_21343
Acyl chain remodeling of DAG and TAG (1) REACT_121122
Aflatoxin activation and detoxification (3) REACT_228214
Agmatine biosynthesis (2) REACT_14800
Alpha-oxidation of phytanate (1) REACT_17003
Amino acid synthesis and interconversion (transamination) (3) REACT_238
Amino acid transport across the plasma membrane (8) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (8) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (8) REACT_75842
Arachidonate production from DAG (1) REACT_19308
Astrocytic Glutamate-Glutamine Uptake And Metabolism (1) REACT_13639
Beta-oxidation of pristanoyl-CoA (1) REACT_17017
Beta-oxidation of very long chain fatty acids (1) REACT_17062
Branched-chain amino acid catabolism (2) REACT_197
Carnitine synthesis (2) REACT_2125
Catecholamine biosynthesis (1) REACT_15551
Citric acid cycle (TCA cycle) (1) REACT_1785
Class A/1 (Rhodopsin-like receptors) (1) REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (2) REACT_18319
Collagen biosynthesis and modifying enzymes (1) REACT_121139
Condensation of Prophase Chromosomes (1) REACT_172744
Conjugation of benzoate with glycine (1) REACT_6933
Conjugation of salicylate with glycine (1) REACT_6812
Creatine metabolism (2) REACT_813
CREB phosphorylation through the activation of CaMKII (2) REACT_20642
Cross-presentation of soluble exogenous antigens (endosomes) (8) REACT_111056
CYP2E1 reactions (1) REACT_13797
Cytosolic tRNA aminoacylation (8) REACT_15306
Degradation of GABA (2) REACT_23964
Endosomal/Vacuolar pathway (8) REACT_111168
eNOS activation (1) REACT_12477
EPHB-mediated forward signaling (2) REACT_228085
ER-Phagosome pathway (8) REACT_111178
Ethanol oxidation (2) REACT_34
Free fatty acid receptors (3) REACT_21268
GABA synthesis (1) REACT_24020
G alpha (i) signalling events (3) REACT_19231
G alpha (q) signalling events (5) REACT_18283
Gluconeogenesis (1) REACT_1520
Glutamate Neurotransmitter Release Cycle (1) REACT_12591
Glutathione synthesis and recycling (8) REACT_6960
Glyoxylate metabolism (2) REACT_16925
HDMs demethylate histones (1) REACT_228178
Heme biosynthesis (1) REACT_9465
Histidine catabolism (1) REACT_1249
HS-GAG biosynthesis (1) REACT_121248
Hydroxycarboxylic acid-binding receptors (1) REACT_163785
Interconversion of polyamines (1) REACT_14805
Ligand-gated ion channel transport (1) REACT_25387
Lysine catabolism (1) REACT_1298
Metabolism of folate and pterines (2) REACT_11167
Metabolism of polyamines (1) REACT_14820
Mitochondrial iron-sulfur cluster biogenesis (1) REACT_150353
Mitochondrial tRNA aminoacylation (8) REACT_15302
Molybdenum cofactor biosynthesis (1) REACT_25073
Na+/Cl- dependent neurotransmitter transporters (7) REACT_20506
Nicotinate metabolism (1) REACT_11088
Nitric oxide stimulates guanylate cyclase (1) REACT_23862
NoRC negatively regulates rRNA expression (1) REACT_200856
Organic anion transport (1) REACT_22310
Organic anion transporters (5) REACT_19372
Oxidative Stress Induced Senescence (1) REACT_169436
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_121226
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_120916
PAOs oxidise polyamines to amines (1) REACT_505
Phagosomal maturation (early endosomal stage) (1) REACT_121256
Phenylalanine and tyrosine catabolism (4) REACT_1786
Presynaptic function of Kainate receptors (1) REACT_21254
Proline catabolism (2) REACT_1002
Proton-coupled monocarboxylate transport (1) REACT_20515
Proton-coupled neutral amino acid transporters (3) REACT_19348
Proton/oligonucleotide cotransporters (8) REACT_19328
Purine ribonucleoside monophosphate biosynthesis (2) REACT_1776
Pyrimidine biosynthesis (1) REACT_21376
Pyrimidine catabolism (1) REACT_1023
Pyruvate metabolism (1) REACT_2071
Ras activation uopn Ca2+ infux through NMDA receptor (2) REACT_20546
Recycling of bile acids and salts (1) REACT_11042
Serine biosynthesis (1) REACT_115789
Sodium-coupled sulphate, di- and tri-carboxylate transporters (1) REACT_20646
Sulfur amino acid metabolism (2) REACT_115639
Synthesis and interconversion of nucleotide di- and triphosphates (1) REACT_21330
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (1) REACT_11041
Synthesis of glycosylphosphatidylinositol (GPI) (1) REACT_952
Synthesis of Leukotrienes (LT) and Eoxins (EX) (2) REACT_150420
Synthesis of UDP-N-acetyl-glucosamine (1) REACT_22394
Synthesis, secretion, and deacylation of Ghrelin (1) REACT_19189
TET1,2,3 and TDG demethylate DNA (1) REACT_200682
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1) REACT_111176
The fatty acid cycling model (1) REACT_6258
Thyroxine biosynthesis (2) REACT_15292
Transport of inorganic cations/anions and amino acids/oligopeptides (2) REACT_19397
Tryptophan catabolism (3) REACT_916
Unblocking of NMDA receptor, glutamate binding and activation (2) REACT_20594
Urea cycle (2) REACT_847
Utilization of Ketone Bodies (1) REACT_59
VEGFR2 mediated vascular permeability (1) REACT_228016
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