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ST001780 Comparative analysis of metabolomic profiles in cerebrospinal fluid before and after endurance exerciseList of human metabolic pathways and metabolites (REACTOME)
Pathway name (# of metabolites detected in study)
Reactome pathway
5-Phosphoribose 1-diphosphate biosynthesis (4)
REACT_850
Abacavir metabolism (10)
REACT_121388
Abacavir transmembrane transport (2)
REACT_120801
ABCA transporters in lipid homeostasis (3)
REACT_111158
ABC-family proteins mediated transport (2)
REACT_15480
ABH2 mediated Reversal of Alkylation Damage (2)
REACT_526
ABH3 mediated Reversal of Alkylation Damage (2)
REACT_1662
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate (3)
REACT_160183
Abnormal metabolism in phenylketonuria (10)
REACT_121117
Acetylation (3)
REACT_6732
Acetylcholine Neurotransmitter Release Cycle (6)
REACT_15309
Acetylcholine regulates insulin secretion (5)
REACT_18405
Activated point mutants of FGFR2 (2)
REACT_120863
activated TAK1 mediates p38 MAPK activation (2)
REACT_21399
Activation of AMPA receptors (1)
REACT_18338
Activation of ATR in response to replication stress (2)
REACT_6769
Activation of BAD and translocation to mitochondria (2)
REACT_549
Activation of CaMK IV (2)
REACT_20652
Activation of Ca-permeable Kainate Receptor (1)
REACT_21346
Activation of caspases through apoptosome-mediated cleavage (2)
REACT_607
Activation of gene expression by SREBF (SREBP) (2)
REACT_147904
Activation of G protein gated Potassium channels (1)
REACT_75831
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon (2)
REACT_25148
Activation of Na-permeable Kainate Receptors (1)
REACT_21343
Activation of NF-kappaB in B cells (2)
REACT_118656
Activation of NIMA Kinases NEK9, NEK6, NEK7 (2)
REACT_160122
Activation of PKB (2)
REACT_790
Activation of PPARGC1A (PGC-1alpha) by phosphorylation (3)
REACT_200686
Activation of Rac (2)
REACT_19226
Activation of RAS in B cells (4)
REACT_118778
Activation of the AP-1 family of transcription factors (2)
REACT_21326
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (2)
REACT_1258
Activation of the phototransduction cascade (3)
REACT_163932
Activation of the pre-replicative complex (2)
REACT_1095
Acyl chain remodeling of CL (1)
REACT_121006
Acyl chain remodeling of DAG and TAG (2)
REACT_121122
Acyl chain remodelling of PC (1)
REACT_120829
Acyl chain remodelling of PE (1)
REACT_121369
Acyl chain remodelling of PG (1)
REACT_121324
Acyl chain remodelling of PI (1)
REACT_120722
Acyl chain remodelling of PS (1)
REACT_121384
Adenosine P1 receptors (1)
REACT_18288
Adenylate cyclase activating pathway (5)
REACT_15312
Adenylate cyclase inhibitory pathway (2)
REACT_15333
Adherens junctions interactions (1)
REACT_19195
ADP signalling through P2Y purinoceptor 1 (4)
REACT_19140
ADP signalling through P2Y purinoceptor 12 (3)
REACT_20653
Adrenaline,noradrenaline inhibits insulin secretion (3)
REACT_18339
Adrenaline signalling through Alpha-2 adrenergic receptor (1)
REACT_19180
Adrenoceptors (1)
REACT_16927
Aflatoxin activation and detoxification (7)
REACT_228214
Agmatine biosynthesis (3)
REACT_14800
AKT-mediated inactivation of FOXO1A (2)
REACT_13655
AKT phosphorylates targets in the cytosol (2)
REACT_12564
AKT phosphorylates targets in the nucleus (2)
REACT_12442
alpha-linolenic acid (ALA) metabolism (11)
REACT_121147
Alpha-oxidation of phytanate (8)
REACT_17003
Amino acid synthesis and interconversion (transamination) (20)
REACT_238
Amino acid transport across the plasma membrane (25)
REACT_13796
AMPK inhibits chREBP transcriptional activation activity (3)
REACT_1988
Androgen biosynthesis (8)
REACT_11059
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (2)
REACT_118700
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (24)
REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (23)
REACT_75842
Arachidonate production from DAG (2)
REACT_19308
Arachidonic acid metabolism (1)
REACT_147851
ARMS-mediated activation (4)
REACT_12002
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (2)
REACT_13721
Association of TriC/CCT with target proteins during biosynthesis (1)
REACT_16907
Astrocytic Glutamate-Glutamine Uptake And Metabolism (4)
REACT_13639
Asymmetric localization of PCP proteins (2)
REACT_172638
A tetrasaccharide linker sequence is required for GAG synthesis (2)
REACT_121408
ATM mediated phosphorylation of repair proteins (2)
REACT_1924
ATM mediated response to DNA double-strand break (2)
REACT_204
ATP sensitive Potassium channels (1)
REACT_75775
Attenuation phase (2)
REACT_200624
Autodegradation of the E3 ubiquitin ligase COP1 (2)
REACT_20549
Axonal growth inhibition (RHOA activation) (2)
REACT_13815
Axonal growth stimulation (1)
REACT_13779
Beta-catenin phosphorylation cascade (2)
REACT_11065
betaKlotho-mediated ligand binding (2)
REACT_111046
Beta oxidation of butanoyl-CoA to acetyl-CoA (3)
REACT_419
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA (5)
REACT_1708
Beta oxidation of hexanoyl-CoA to butanoyl-CoA (5)
REACT_1887
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA (5)
REACT_735
Beta oxidation of myristoyl-CoA to lauroyl-CoA (5)
REACT_2108
Beta oxidation of octanoyl-CoA to hexanoyl-CoA (5)
REACT_1697
Beta oxidation of palmitoyl-CoA to myristoyl-CoA (5)
REACT_2025
Beta-oxidation of pristanoyl-CoA (5)
REACT_17017
Beta-oxidation of very long chain fatty acids (5)
REACT_17062
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (3)
REACT_416
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (3)
REACT_22433
Biotin transport and metabolism (5)
REACT_11153
BMAL1:CLOCK,NPAS2 activates circadian gene expression (2)
REACT_111118
Branched-chain amino acid catabolism (13)
REACT_197
Butyrate Response Factor 1 (BRF1) destabilizes mRNA (2)
REACT_24915
Ca2+ pathway (5)
REACT_172761
Calmodulin induced events (2)
REACT_9000
CaMK IV-mediated phosphorylation of CREB (2)
REACT_15502
Cam-PDE 1 activation (2)
REACT_15408
Carnitine synthesis (5)
REACT_2125
Catecholamine biosynthesis (6)
REACT_15551
CD28 co-stimulation (2)
REACT_19183
CD28 dependent PI3K/Akt signaling (2)
REACT_19358
CD28 dependent Vav1 pathway (4)
REACT_19238
CDK-mediated phosphorylation and removal of Cdc6 (2)
REACT_1221
CDO in myogenesis (3)
REACT_21402
Cell-extracellular matrix interactions (1)
REACT_20649
Cell redox homeostasis (5)
REACT_121394
Cell surface interactions at the vascular wall (1)
REACT_12051
cGMP effects (1)
REACT_23767
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (2)
REACT_407
CHL1 interactions (1)
REACT_22292
Cholesterol biosynthesis (16)
REACT_9405
Chondroitin sulfate biosynthesis (2)
REACT_120989
Chylomicron-mediated lipid transport (1)
REACT_6841
Circadian Clock (2)
REACT_24941
Citric acid cycle (TCA cycle) (17)
REACT_1785
Class A/1 (Rhodopsin-like receptors) (8)
REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (5)
REACT_18319
Class II GLUTs (1)
REACT_19281
Clathrin derived vesicle budding (2)
REACT_19187
Clearance of Nuclear Envelope Membranes from Chromatin (2)
REACT_160251
Cleavage of the damaged purine (2)
REACT_1729
Cleavage of the damaged pyrimidine (2)
REACT_2156
Cobalamin (Cbl, vitamin B12) transport and metabolism (12)
REACT_163862
Coenzyme A biosynthesis (7)
REACT_11218
Collagen biosynthesis and modifying enzymes (4)
REACT_121139
Condensation of Prometaphase Chromosomes (2)
REACT_150260
Condensation of Prophase Chromosomes (6)
REACT_172744
Conjugation of benzoate with glycine (7)
REACT_6933
Conjugation of phenylacetate with glutamine (6)
REACT_6800
Conjugation of salicylate with glycine (6)
REACT_6812
Constitutive PI3K/AKT Signaling in Cancer (2)
REACT_147727
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants (2)
REACT_160254
Constitutive Signaling by NOTCH1 PEST Domain Mutants (2)
REACT_160243
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (1)
REACT_6867
COPII (Coat Protein 2) Mediated Vesicle Transport (2)
REACT_12507
COPI Mediated Transport (2)
REACT_11096
COX reactions (1)
REACT_1396
Creatine metabolism (10)
REACT_813
CREB phosphorylation (2)
REACT_12524
CREB phosphorylation through the activation of Adenylate Cyclase (4)
REACT_20625
CREB phosphorylation through the activation of CaMKII (4)
REACT_20642
CREB phosphorylation through the activation of CaMKK (2)
REACT_20661
CREB phosphorylation through the activation of Ras (3)
REACT_20568
CRMPs in Sema3A signaling (2)
REACT_19199
Cross-presentation of particulate exogenous antigens (phagosomes) (2)
REACT_111174
Cross-presentation of soluble exogenous antigens (endosomes) (20)
REACT_111056
c-src mediated regulation of Cx43 function and closure of gap junctions (2)
REACT_11043
CTLA4 inhibitory signaling (2)
REACT_19405
Cyclin A/B1 associated events during G2/M transition (2)
REACT_1857
Cyclin A:Cdk2-associated events at S phase entry (2)
REACT_9029
Cyclin B2 mediated events (2)
REACT_2101
Cyclin D associated events in G1 (2)
REACT_821
Cyclin E associated events during G1/S transition (2)
REACT_1574
CYP2E1 reactions (2)
REACT_13797
Cysteine formation from homocysteine (5)
REACT_115589
Cytosolic iron-sulfur cluster assembly (4)
REACT_160176
Cytosolic sulfonation of small molecules (9)
REACT_6913
Cytosolic tRNA aminoacylation (23)
REACT_15306
DAG and IP3 signaling (2)
REACT_111064
DAP12 signaling (4)
REACT_147814
DARPP-32 events (4)
REACT_15334
DCC mediated attractive signaling (4)
REACT_22351
deactivation of the beta-catenin transactivating complex (2)
REACT_200731
Deadenylation of mRNA (1)
REACT_20514
Defective B3GAT3 causes JDSSDHD (1)
REACT_267659
Defective CHSY1 causes TPBS (1)
REACT_267682
Defective EXT1 causes exostoses 1, TRPS2 and CHDS (1)
REACT_267674
Defective EXT2 causes exostoses 2 (1)
REACT_267654
Defective HLCS causes multiple carboxylase deficiency (2)
REACT_169312
Defective MMAB causes methylmalonic aciduria type cblB (1)
REACT_169318
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC (1)
REACT_169169
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG (3)
REACT_169149
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE (4)
REACT_169439
Defective PAPSS2 causes SEMD-PA (2)
REACT_267645
degradation of AXIN (2)
REACT_200766
Degradation of beta-catenin by the destruction complex (2)
REACT_11063
Degradation of cysteine and homocysteine (8)
REACT_115654
Degradation of GABA (7)
REACT_23964
Degradation of GLI1 by the proteasome (2)
REACT_267605
Degradation of GLI2 by the proteasome (2)
REACT_206597
Depolymerisation of the Nuclear Lamina (2)
REACT_200828
Detoxification of Reactive Oxygen Species (6)
REACT_172715
Digestion of dietary lipid (8)
REACT_9518
disassembly of the destruction complex and recruitment of AXIN to the membrane (2)
REACT_200610
Disinhibition of SNARE formation (2)
REACT_1178
DNA Damage/Telomere Stress Induced Senescence (2)
REACT_169185
DNA methylation (2)
REACT_267652
DNA replication initiation (3)
REACT_2244
Dopamine clearance from the synaptic cleft (1)
REACT_15514
Dopamine Neurotransmitter Release Cycle (3)
REACT_15293
Dopamine receptors (1)
REACT_16968
Downregulation of ERBB2:ERBB3 signaling (2)
REACT_115662
Downregulation of SMAD2/3:SMAD4 transcriptional activity (2)
REACT_121111
Downstream signal transduction (4)
REACT_17025
Downstream TCR signaling (3)
REACT_12555
DSCAM interactions (3)
REACT_25299
Effects of PIP2 hydrolysis (2)
REACT_2202
EGFR downregulation (3)
REACT_12484
EGFR interacts with phospholipase C-gamma (2)
REACT_12478
EGFR Transactivation by Gastrin (2)
REACT_121096
Eicosanoids (3)
REACT_13645
Electron transport from NADPH to Ferredoxin (3)
REACT_150128
Elevation of cytosolic Ca2+ levels (1)
REACT_162
Endogenous sterols (14)
REACT_13812
Endosomal Sorting Complex Required For Transport (ESCRT) (2)
REACT_27258
Endosomal/Vacuolar pathway (20)
REACT_111168
eNOS activation (8)
REACT_12477
Enzymatic degradation of dopamine by COMT (4)
REACT_15548
Enzymatic degradation of Dopamine by monoamine oxidase (3)
REACT_15511
EPHA-mediated growth cone collapse (4)
REACT_228063
EPHB-mediated forward signaling (6)
REACT_228085
EPH-ephrin mediated repulsion of cells (4)
REACT_228189
EPH-Ephrin signaling (2)
REACT_228170
Ephrin signaling (4)
REACT_228226
ERK1 activation (2)
REACT_1391
ERK2 activation (2)
REACT_1183
ERK/MAPK targets (2)
REACT_12599
ER-Phagosome pathway (22)
REACT_111178
Establishment of Sister Chromatid Cohesion (2)
REACT_150266
Estrogen biosynthesis (5)
REACT_11037
Ethanol oxidation (7)
REACT_34
Eukaryotic Translation Elongation (2)
REACT_1477
Eukaryotic Translation Termination (2)
REACT_1986
Factors involved in megakaryocyte development and platelet production (5)
REACT_24970
Fatty acids (7)
REACT_13814
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (3)
REACT_19193
Fatty acid, triacylglycerol, and ketone body metabolism (2)
REACT_22279
Fatty Acyl-CoA Biosynthesis (9)
REACT_1319
Fc epsilon receptor (FCERI) signaling (2)
REACT_163936
FCERI mediated Ca+2 mobilization (2)
REACT_163834
FCERI mediated MAPK activation (4)
REACT_163701
FCERI mediated NF-kB activation (4)
REACT_163994
FCGR activation (2)
REACT_160274
FGFR1b ligand binding and activation (2)
REACT_9400
FGFR1c and Klotho ligand binding and activation (2)
REACT_9484
FGFR1c ligand binding and activation (2)
REACT_9515
FGFR2b ligand binding and activation (2)
REACT_9416
FGFR2c ligand binding and activation (2)
REACT_9413
FGFR3b ligand binding and activation (2)
REACT_9508
FGFR3c ligand binding and activation (2)
REACT_9510
FGFR4 ligand binding and activation (2)
REACT_9452
FMO oxidises nucleophiles (4)
REACT_13653
Folding of actin by CCT/TriC (2)
REACT_17050
Formation of apoptosome (2)
REACT_89
Formation of ATP by chemiosmotic coupling (2)
REACT_6759
Formation of HIV-1 elongation complex containing HIV-1 Tat (2)
REACT_6346
Formation of the active cofactor, UDP-glucuronate (5)
REACT_6737
formation of the beta-catenin:TCF transactivating complex (4)
REACT_200753
Formation of the ternary complex, and subsequently, the 43S complex (1)
REACT_1079
Formation of tubulin folding intermediates by CCT/TriC (3)
REACT_16956
Formyl peptide receptors bind formyl peptides and many other ligands (1)
REACT_21264
Free fatty acid receptors (2)
REACT_21268
Frs2-mediated activation (4)
REACT_12076
FRS2-mediated cascade (4)
REACT_21247
Fructose catabolism (3)
REACT_1571
G0 and Early G1 (2)
REACT_111214
G2/M DNA damage checkpoint (2)
REACT_897
G2/M DNA replication checkpoint (2)
REACT_1846
G2 Phase (2)
REACT_1915
GAB1 signalosome (2)
REACT_12578
GABA A receptor activation (1)
REACT_24987
GABA A (rho) receptor activation (1)
REACT_25168
GABA B receptor activation (1)
REACT_25031
GABA synthesis (3)
REACT_24020
GABA synthesis, release, reuptake and degradation (1)
REACT_23947
Galactose catabolism (3)
REACT_532
G alpha (12/13) signalling events (3)
REACT_18407
G alpha (i) signalling events (24)
REACT_19231
G alpha (q) signalling events (19)
REACT_18283
G alpha (s) signalling events (16)
REACT_19327
G alpha (z) signalling events (6)
REACT_19333
Gap junction assembly (2)
REACT_9509
Gastrin-CREB signalling pathway via PKC and MAPK (2)
REACT_120966
G beta:gamma signalling through PI3Kgamma (2)
REACT_19290
Generation of second messenger molecules (2)
REACT_12623
GLI3 is processed to GLI3R by the proteasome (2)
REACT_231645
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (5)
REACT_18274
Glucagon signaling in metabolic regulation (2)
REACT_1665
Glucagon-type ligand receptors (1)
REACT_18377
Glucocorticoid biosynthesis (9)
REACT_11036
Gluconeogenesis (19)
REACT_1520
Glucose transport (2)
REACT_212
Glucuronidation (2)
REACT_6784
Glutamate Neurotransmitter Release Cycle (2)
REACT_12591
Glutathione conjugation (1)
REACT_6926
Glutathione synthesis and recycling (25)
REACT_6960
Glycogen breakdown (glycogenolysis) (3)
REACT_1008
Glycogen synthesis (4)
REACT_169208
Glycolysis (11)
REACT_1383
Glycosphingolipid metabolism (8)
REACT_116105
Glyoxylate metabolism (10)
REACT_16925
Golgi Associated Vesicle Biogenesis (4)
REACT_19400
Golgi Cisternae Pericentriolar Stack Reorganization (3)
REACT_1100
G-protein activation (2)
REACT_15457
GPVI-mediated activation cascade (4)
REACT_1695
GRB2 events in EGFR signaling (2)
REACT_12606
GRB2 events in ERBB2 signaling (2)
REACT_115854
GRB2:SOS provides linkage to MAPK signaling for Integrins (1)
REACT_15443
Growth hormone receptor signaling (2)
REACT_111133
GTP hydrolysis and joining of the 60S ribosomal subunit (2)
REACT_2085
HATs acetylate histones (2)
REACT_172610
HCN channels (1)
REACT_75862
HDL-mediated lipid transport (3)
REACT_13621
HDMs demethylate histones (2)
REACT_228178
Hedgehog ligand biogenesis (4)
REACT_228111
Hedgehog 'off' state (5)
REACT_267634
Heme biosynthesis (5)
REACT_9465
Heme degradation (4)
REACT_22297
Hh ligand biogenesis disease (2)
REACT_228209
Highly calcium permeable nicotinic acetylcholine receptors (1)
REACT_22352
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (1)
REACT_22303
Highly sodium permeable acetylcholine nicotinic receptors (1)
REACT_22223
Histamine receptors (1)
REACT_16903
Histidine catabolism (5)
REACT_1249
HIV Transcription Initiation (1)
REACT_6332
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis (4)
REACT_494
HSF1-dependent transactivation (2)
REACT_200775
HS-GAG biosynthesis (3)
REACT_121248
HS-GAG degradation (3)
REACT_120752
HuR stabilizes mRNA (2)
REACT_25218
Hydrolysis of LPC (2)
REACT_120977
Hydrolysis of LPE (2)
REACT_120785
Hydroxycarboxylic acid-binding receptors (2)
REACT_163785
Hypusine synthesis from eIF5A-lysine (3)
REACT_12469
Import of palmitoyl-CoA into the mitochondrial matrix (5)
REACT_11082
Inactivation of Cdc42 and Rac (2)
REACT_19342
Inactivation, recovery and regulation of the phototransduction cascade (8)
REACT_163919
Inhibition of TSC complex formation by PKB (2)
REACT_6743
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (1)
REACT_25004
Inositol transporters (1)
REACT_19188
Insulin effects increased synthesis of Xylulose-5-Phosphate (2)
REACT_939
Integrin alphaIIb beta3 signaling (4)
REACT_15523
Interaction between L1 and Ankyrins (2)
REACT_22266
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (2)
REACT_25367
Interconversion of polyamines (5)
REACT_14805
Interferon alpha/beta signaling (2)
REACT_25162
Interferon gamma signaling (2)
REACT_25078
Interleukin-1 signaling (2)
REACT_22442
Interleukin-2 signaling (2)
REACT_27283
Interleukin-3, 5 and GM-CSF signaling (2)
REACT_23837
Interleukin-6 signaling (2)
REACT_27307
Interleukin-7 signaling (2)
REACT_115529
Interleukin receptor SHC signaling (4)
REACT_23891
Ion transport by P-type ATPases (2)
REACT_25149
IRAK1 recruits IKK complex (2)
REACT_24918
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (2)
REACT_25354
IRAK2 mediated activation of TAK1 complex (2)
REACT_25380
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (2)
REACT_25018
IRE1alpha activates chaperones (2)
REACT_18368
IRF3 mediated activation of type 1 IFN (2)
REACT_118811
IRF3-mediated induction of type I IFN (2)
REACT_163993
Iron uptake and transport (4)
REACT_25060
IRS activation (2)
REACT_570
IRS-related events triggered by IGF1R (2)
REACT_150203
ISG15 antiviral mechanism (3)
REACT_115831
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (2)
REACT_21368
Keratan sulfate biosynthesis (3)
REACT_121120
Kinesins (4)
REACT_25201
KSRP destabilizes mRNA (2)
REACT_25042
L13a-mediated translational silencing of Ceruloplasmin expression (1)
REACT_79
L1CAM interactions (2)
REACT_22205
Late Phase of HIV Life Cycle (1)
REACT_6361
LDL-mediated lipid transport (1)
REACT_6934
Leukotriene receptors (1)
REACT_18302
Ligand-gated ion channel transport (3)
REACT_25387
Linoleic acid (LA) metabolism (10)
REACT_121100
Loss of Nlp from mitotic centrosomes (2)
REACT_15364
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (2)
REACT_163743
Lysine catabolism (10)
REACT_1298
Lysosome Vesicle Biogenesis (4)
REACT_19287
Lysosphingolipid and LPA receptors (1)
REACT_18365
MASTL Facilitates Mitotic Progression (2)
REACT_150182
Meiotic recombination (2)
REACT_27271
Meiotic synapsis (2)
REACT_75792
MEK activation (1)
REACT_962
Membrane binding and targetting of GAG proteins (1)
REACT_115893
Metabolism of folate and pterines (9)
REACT_11167
Metabolism of nucleotides (10)
REACT_1698
Metabolism of polyamines (5)
REACT_14820
Metabolism of serotonin (5)
REACT_15532
Methionine salvage pathway (4)
REACT_75881
Methylation (11)
REACT_6946
MHC class II antigen presentation (4)
REACT_121399
MicroRNA (miRNA) biogenesis (2)
REACT_12417
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (2)
REACT_11039
Mineralocorticoid biosynthesis (7)
REACT_11047
Minus-strand DNA synthesis (4)
REACT_9055
Miscellaneous substrates (5)
REACT_13425
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) (7)
REACT_228019
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (7)
REACT_228145
Mitochondrial ABC transporters (2)
REACT_111108
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids (5)
REACT_160
Mitochondrial iron-sulfur cluster biogenesis (3)
REACT_150353
Mitochondrial protein import (2)
REACT_118595
Mitochondrial translation elongation (2)
REACT_267677
Mitochondrial translation initiation (2)
REACT_267680
Mitochondrial translation termination (2)
REACT_267602
Mitochondrial tRNA aminoacylation (23)
REACT_15302
Mitotic Prometaphase (2)
REACT_682
Molybdenum cofactor biosynthesis (9)
REACT_25073
MPS IIIC - Sanfilippo syndrome C (1)
REACT_147860
mRNA 3'-end processing (1)
REACT_1849
mRNA Capping (5)
REACT_1470
mRNA decay by 3' to 5' exoribonuclease (4)
REACT_20619
mRNA decay by 5' to 3' exoribonuclease (4)
REACT_20518
Mtb iron assimilation by chelation (2)
REACT_121118
mTOR signalling (2)
REACT_6838
Muscarinic acetylcholine receptors (1)
REACT_16943
MyD88 cascade initiated on plasma membrane (2)
REACT_27215
MyD88 dependent cascade initiated on endosome (2)
REACT_25222
MyD88:Mal cascade initiated on plasma membrane (2)
REACT_6788
Na+/Cl- dependent neurotransmitter transporters (26)
REACT_20506
NADPH regeneration (3)
REACT_16904
NCAM1 interactions (1)
REACT_18312
NCAM signaling for neurite out-growth (4)
REACT_18334
Negative regulation of FGFR signaling (2)
REACT_111184
Negative regulators of RIG-I/MDA5 signaling (1)
REACT_25271
Nephrin interactions (2)
REACT_23832
NEP/NS2 Interacts with the Cellular Export Machinery (2)
REACT_6179
Netrin-1 signaling (2)
REACT_22237
Netrin mediated repulsion signals (2)
REACT_22384
Neurofascin interactions (2)
REACT_22312
Neurotransmitter Clearance In The Synaptic Cleft (2)
REACT_13583
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 (1)
REACT_25039
NF-kB is activated and signals survival (2)
REACT_13696
NGF-independant TRKA activation (1)
REACT_11046
N-glycan trimming and elongation in the cis-Golgi (1)
REACT_25210
Nicotinamide salvaging (4)
REACT_11213
Nicotinate metabolism (8)
REACT_11088
Nitric oxide stimulates guanylate cyclase (6)
REACT_23862
NOD1/2 Signaling Pathway (2)
REACT_75776
Nonhomologous End-joining (NHEJ) (2)
REACT_1022
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (3)
REACT_75822
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (1)
REACT_75768
NoRC negatively regulates rRNA expression (2)
REACT_200856
Norepinephrine Neurotransmitter Release Cycle (4)
REACT_15418
NOSIP mediated eNOS trafficking (2)
REACT_12510
NOSTRIN mediated eNOS trafficking (2)
REACT_12541
NOTCH1 Intracellular Domain Regulates Transcription (2)
REACT_118780
NRAGE signals death through JNK (4)
REACT_13638
NRIF signals cell death from the nucleus (2)
REACT_13643
Nuclear import of Rev protein (2)
REACT_9395
Nuclear Pore Complex (NPC) Disassembly (2)
REACT_163931
O-linked glycosylation of mucins (1)
REACT_115606
Oncogene Induced Senescence (2)
REACT_169325
Orc1 removal from chromatin (2)
REACT_1156
Organic anion transport (5)
REACT_22310
Organic anion transporters (5)
REACT_19372
Organic cation transport (11)
REACT_22357
Orphan transporters (15)
REACT_267716
Oxidative Stress Induced Senescence (6)
REACT_169436
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha (2)
REACT_121226
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (2)
REACT_120916
p130Cas linkage to MAPK signaling for integrins (3)
REACT_15381
P2Y receptors (4)
REACT_18289
p38MAPK events (4)
REACT_12065
p53-Independent DNA Damage Response (2)
REACT_2160
p75NTR recruits signalling complexes (2)
REACT_13415
PAOs oxidise polyamines to amines (3)
REACT_505
Passive transport by Aquaporins (2)
REACT_23826
PCP/CE pathway (3)
REACT_172581
PD-1 signaling (3)
REACT_19324
PDE3B signalling (4)
REACT_1451
PECAM1 interactions (2)
REACT_12519
Pentose phosphate pathway (hexose monophosphate shunt) (4)
REACT_1859
Peptide chain elongation (2)
REACT_1404
PERK regulates gene expression (2)
REACT_18277
Peroxisomal lipid metabolism (1)
REACT_16957
Phagosomal maturation (early endosomal stage) (6)
REACT_121256
Phenylalanine and tyrosine catabolism (11)
REACT_1786
Phosphate bond hydrolysis by NUDT proteins (4)
REACT_150237
Phospholipase C-mediated cascade (2)
REACT_21310
phospho-PLA2 pathway (3)
REACT_15466
Phosphorylation of CD3 and TCR zeta chains (2)
REACT_12582
Phosphorylation of Emi1 (2)
REACT_6875
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes (2)
REACT_308
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes (2)
REACT_6362
PI3K/AKT activation (2)
REACT_12464
PI-3K cascade (2)
REACT_21270
PI3K Cascade (2)
REACT_976
PI3K events in ERBB2 signaling (2)
REACT_116008
PI3K events in ERBB4 signaling (2)
REACT_115961
PIP3 activates AKT signaling (2)
REACT_75829
PKA activation (3)
REACT_15530
PKA activation in glucagon signalling (4)
REACT_1946
PKA-mediated phosphorylation of CREB (2)
REACT_15497
PKA-mediated phosphorylation of key metabolic factors (2)
REACT_1525
Plasmalogen biosynthesis (5)
REACT_1407
Platelet degranulation (6)
REACT_318
Platelet homeostasis (1)
REACT_23876
Platelet sensitization by LDL (3)
REACT_23879
PLC beta mediated events (2)
REACT_15426
PLCG1 events in ERBB2 signaling (2)
REACT_115720
Polo-like kinase mediated events (2)
REACT_1006
Polymerase switching (2)
REACT_1792
Polymerase switching on the C-strand of the telomere (2)
REACT_7987
Post-chaperonin tubulin folding pathway (1)
REACT_16967
PPARA activates gene expression (5)
REACT_116145
PRC2 methylates histones and DNA (2)
REACT_200808
Prefoldin mediated transfer of substrate to CCT/TriC (1)
REACT_16936
Pregnenolone biosynthesis (3)
REACT_11038
Pre-NOTCH Processing in Golgi (2)
REACT_118798
Pre-NOTCH Processing in the Endoplasmic Reticulum (2)
REACT_118722
Presynaptic function of Kainate receptors (1)
REACT_21254
Processive synthesis on the C-strand of the telomere (3)
REACT_8027
Prolactin receptor signaling (2)
REACT_115697
Proline catabolism (5)
REACT_1002
Propionyl-CoA catabolism (2)
REACT_993
Prostacyclin signalling through prostacyclin receptor (2)
REACT_23946
Prostanoid ligand receptors (3)
REACT_18425
Proton-coupled monocarboxylate transport (3)
REACT_20515
Proton-coupled neutral amino acid transporters (3)
REACT_19348
Proton/oligonucleotide cotransporters (20)
REACT_19328
Purine catabolism (19)
REACT_2086
Purine ribonucleoside monophosphate biosynthesis (15)
REACT_1776
Purine salvage (19)
REACT_1923
Pyrimidine biosynthesis (16)
REACT_21376
Pyrimidine catabolism (20)
REACT_1023
Pyrimidine salvage reactions (13)
REACT_655
Pyruvate metabolism (7)
REACT_2071
RAF activation (3)
REACT_2077
RAF phosphorylates MEK (3)
REACT_614
Rap1 signalling (6)
REACT_23898
Ras activation uopn Ca2+ infux through NMDA receptor (4)
REACT_20546
Reactions specific to the complex N-glycan synthesis pathway (1)
REACT_25302
Recruitment of NuMA to mitotic centrosomes (4)
REACT_15510
Recycling of bile acids and salts (13)
REACT_11042
Recycling of eIF2:GDP (2)
REACT_1815
Recycling pathway of L1 (4)
REACT_22365
Regulation by TREX1 (4)
REACT_163652
Regulation of actin dynamics for phagocytic cup formation (4)
REACT_160086
Regulation of AMPK activity via LKB1 (3)
REACT_21285
Regulation of APC/C activators between G1/S and early anaphase (2)
REACT_6837
Regulation of cholesterol biosynthesis by SREBP (SREBF) (2)
REACT_147797
Regulation of HSF1-mediated heat shock response (4)
REACT_200780
Regulation of insulin secretion (4)
REACT_18325
Regulation of KIT signaling (2)
REACT_111225
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (2)
REACT_19241
Regulation of ornithine decarboxylase (ODC) (1)
REACT_13565
Regulation of PLK1 Activity at G2/M Transition (3)
REACT_160315
Regulation of pyruvate dehydrogenase (PDH) complex (6)
REACT_12528
Regulation of Rheb GTPase activity by AMPK (5)
REACT_21393
Regulation of signaling by CBL (2)
REACT_23787
Regulation of thyroid hormone activity (3)
REACT_15297
Release of eIF4E (3)
REACT_6836
Removal of DNA patch containing abasic residue (1)
REACT_2192
Removal of the Flap Intermediate (4)
REACT_70
Removal of the Flap Intermediate from the C-strand (4)
REACT_7999
Resolution of AP sites via the single-nucleotide replacement pathway (1)
REACT_933
Resolution of Sister Chromatid Cohesion (6)
REACT_150425
Respiratory electron transport (6)
REACT_22393
Retinoid cycle disease events (4)
REACT_160130
Retinoid metabolism and transport (7)
REACT_24968
Retrograde neurotrophin signalling (2)
REACT_12435
Reuptake of GABA (3)
REACT_23910
REV-ERBA represses gene expression (2)
REACT_118789
Rev-mediated nuclear export of HIV RNA (2)
REACT_6190
Rho GTPase cycle (2)
REACT_11051
Ribosomal scanning and start codon recognition (3)
REACT_931
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways (1)
REACT_25359
RIP-mediated NFkB activation via ZBP1 (2)
REACT_118563
RMTs methylate histone arginines (4)
REACT_228108
RNA Polymerase II HIV Promoter Escape (1)
REACT_6253
RNA Polymerase II Promoter Escape (1)
REACT_2089
RNA Polymerase II Transcription Initiation (1)
REACT_1851
RNA Polymerase II Transcription Initiation And Promoter Clearance (2)
REACT_834
RNA Polymerase I Promoter Opening (1)
REACT_2232
RNA Polymerase I Transcription Initiation (2)
REACT_953
Role of Abl in Robo-Slit signaling (2)
REACT_19230
Role of DCC in regulating apoptosis (2)
REACT_22128
Role of LAT2/NTAL/LAB on calcium mobilization (2)
REACT_163769
Role of phospholipids in phagocytosis (4)
REACT_160158
Role of second messengers in netrin-1 signaling (2)
REACT_22228
RORA activates circadian gene expression (2)
REACT_118659
RSK activation (2)
REACT_20510
S33 mutants of beta-catenin aren't phosphorylated (1)
REACT_228159
S37 mutants of beta-catenin aren't phosphorylated (1)
REACT_228251
S45 mutants of beta-catenin aren't phosphorylated (1)
REACT_228137
S6K1-mediated signalling (3)
REACT_6754
S6K1 signalling (2)
REACT_6772
Scavenging by Class A Receptors (4)
REACT_163699
Scavenging by Class B Receptors (2)
REACT_163679
Scavenging by Class F Receptors (2)
REACT_163813
Scavenging by Class H Receptors (1)
REACT_164002
Scavenging of heme from plasma (1)
REACT_160163
SCF(Skp2)-mediated degradation of p27/p21 (2)
REACT_9003
Sema3A PAK dependent Axon repulsion (3)
REACT_19236
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion (4)
REACT_19279
Sema4D induced cell migration and growth-cone collapse (4)
REACT_19277
Sema4D mediated inhibition of cell attachment and migration (4)
REACT_19266
Senescence-Associated Secretory Phenotype (SASP) (4)
REACT_169168
Separation of Sister Chromatids (4)
REACT_150471
Serine biosynthesis (7)
REACT_115789
Serotonin and melatonin biosynthesis (8)
REACT_15439
Serotonin clearance from the synaptic cleft (1)
REACT_15391
Serotonin Neurotransmitter Release Cycle (3)
REACT_15425
Serotonin receptors (1)
REACT_17064
SHC1 events in EGFR signaling (4)
REACT_12579
SHC1 events in ERBB2 signaling (4)
REACT_115993
SHC1 events in ERBB4 signaling (4)
REACT_116005
SHC activation (2)
REACT_1661
SHC-mediated cascade (4)
REACT_21374
SHC-mediated signalling (2)
REACT_661
SHC-related events triggered by IGF1R (2)
REACT_150139
Sialic acid metabolism (7)
REACT_200874
Signal attenuation (2)
REACT_508
Signaling by activated point mutants of FGFR1 (2)
REACT_121153
Signaling by activated point mutants of FGFR3 (2)
REACT_121337
Signaling by Activin (2)
REACT_150238
Signaling by BMP (2)
REACT_12034
Signaling by constitutively active EGFR (4)
REACT_115852
Signaling by EGFR (2)
REACT_9417
Signaling by ERBB2 (2)
REACT_115755
Signaling by ERBB4 (2)
REACT_115596
Signaling by FGFR (2)
REACT_9470
Signaling by FGFR1 amplification mutants (2)
REACT_120827
Signaling by FGFR1 fusion mutants (2)
REACT_121141
Signaling by FGFR2 amplification mutants (2)
REACT_121255
Signaling by FGFR4 mutants (2)
REACT_121286
Signaling by FGFR mutants (4)
REACT_121398
Signaling by Hippo (2)
REACT_118607
Signaling by Insulin receptor (2)
REACT_498
Signaling by Leptin (2)
REACT_169118
Signaling by NODAL (2)
REACT_111057
Signaling by PDGF (2)
REACT_16888
Signaling by SCF-KIT (4)
REACT_111040
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (2)
REACT_150359
Signalling to ERK5 (2)
REACT_12020
Signalling to p38 via RIT and RIN (2)
REACT_12077
Signalling to RAS (2)
REACT_12033
Signalling to STAT3 (2)
REACT_12049
Signal regulatory protein (SIRP) family interactions (2)
REACT_23916
Signal transduction by L1 (4)
REACT_22272
SIRT1 negatively regulates rRNA Expression (4)
REACT_200827
SMAD2/3 MH2 Domain Mutants in Cancer (2)
REACT_169165
SMAD2/3 Phosphorylation Motif Mutants in Cancer (1)
REACT_169103
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (2)
REACT_120734
Smooth Muscle Contraction (2)
REACT_20558
snRNP Assembly (1)
REACT_11066
Sodium-coupled sulphate, di- and tri-carboxylate transporters (2)
REACT_20646
SOS-mediated signalling (2)
REACT_524
Sphingolipid de novo biosynthesis (13)
REACT_115810
Spry regulation of FGF signaling (2)
REACT_111080
Stabilization of p53 (2)
REACT_309
STAT6-mediated induction of chemokines (2)
REACT_163734
Sterols are 12-hydroxylated by CYP8B1 (2)
REACT_13438
Stimulation of the cell death response by PAK-2p34 (2)
REACT_13532
Stimuli-sensing channels (4)
REACT_160189
STING mediated induction of host immune responses (3)
REACT_147841
Striated Muscle Contraction (2)
REACT_16969
Sulfide oxidation to sulfate (4)
REACT_116010
Sulfur amino acid metabolism (16)
REACT_115639
SUMO is conjugated to E1 (UBA2:SAE1) (3)
REACT_163812
Synthesis and interconversion of nucleotide di- and triphosphates (31)
REACT_21330
Synthesis of 12-eicosatetraenoic acid derivatives (2)
REACT_150201
Synthesis of 15-eicosatetraenoic acid derivatives (6)
REACT_150422
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (4)
REACT_150134
Synthesis of 5-eicosatetraenoic acids (4)
REACT_150209
Synthesis of bile acids and bile salts (5)
REACT_11054
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (9)
REACT_11053
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (7)
REACT_11048
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (19)
REACT_11041
Synthesis of CL (1)
REACT_120920
Synthesis of Dolichyl-phosphate (8)
REACT_22230
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) (10)
REACT_150417
Synthesis of GDP-mannose (2)
REACT_22423
Synthesis of glycosylphosphatidylinositol (GPI) (2)
REACT_952
Synthesis of Hepoxilins (HX) and Trioxilins (TrX) (1)
REACT_150292
Synthesis of IP2, IP, and Ins in the cytosol (2)
REACT_150352
Synthesis of IP3 and IP4 in the cytosol (2)
REACT_150312
Synthesis of IPs in the nucleus (2)
REACT_150275
Synthesis of Ketone Bodies (5)
REACT_1464
Synthesis of Leukotrienes (LT) and Eoxins (EX) (7)
REACT_150420
Synthesis of Lipoxins (LX) (5)
REACT_150320
Synthesis of PA (6)
REACT_120906
Synthesis of PC (11)
REACT_121238
Synthesis of PE (8)
REACT_120919
Synthesis of PG (6)
REACT_121280
Synthesis of PI (4)
REACT_121000
Synthesis of PIPs at the early endosome membrane (2)
REACT_120756
Synthesis of PIPs at the ER membrane (2)
REACT_121168
Synthesis of PIPs at the Golgi membrane (3)
REACT_120836
Synthesis of PIPs at the late endosome membrane (2)
REACT_120918
Synthesis of PIPs at the plasma membrane (2)
REACT_121025
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (15)
REACT_150149
Synthesis of PS (3)
REACT_120823
Synthesis of pyrophosphates in the cytosol (2)
REACT_150188
Synthesis of UDP-N-acetyl-glucosamine (7)
REACT_22394
Synthesis of very long-chain fatty acyl-CoAs (7)
REACT_380
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (3)
REACT_24019
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (2)
REACT_23824
t(4;14) translocations of FGFR3 (2)
REACT_121011
T41 mutants of beta-catenin aren't phosphorylated (1)
REACT_228261
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (2)
REACT_21281
Telomere C-strand synthesis initiation (3)
REACT_7993
Telomere Extension By Telomerase (3)
REACT_7974
Termination of O-glycan biosynthesis (1)
REACT_115835
TET1,2,3 and TDG demethylate DNA (3)
REACT_200682
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (9)
REACT_111176
TGF-beta receptor signaling activates SMADs (2)
REACT_120850
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (2)
REACT_120726
TGFBR1 KD Mutants in Cancer (2)
REACT_169263
TGFBR2 Kinase Domain Mutants in Cancer (1)
REACT_169440
The activation of arylsulfatases (2)
REACT_121036
The canonical retinoid cycle in rods (twilight vision) (9)
REACT_160156
The NLRP1 inflammasome (1)
REACT_75927
The NLRP3 inflammasome (1)
REACT_75808
The proton buffering model (4)
REACT_6196
The retinoid cycle in cones (daylight vision) (4)
REACT_160083
Thrombin signalling through proteinase activated receptors (PARs) (2)
REACT_21384
Thromboxane signalling through TP receptor (2)
REACT_20647
Thyroxine biosynthesis (6)
REACT_15292
Tie2 Signaling (4)
REACT_12621
Tolerance by Mtb to nitric oxide produced by macrophages (2)
REACT_120983
TRAF3-dependent IRF activation pathway (2)
REACT_25026
TRAF6 mediated induction of TAK1 complex (2)
REACT_25351
TRAF6 mediated IRF7 activation (2)
REACT_24938
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling (2)
REACT_25120
TRAF6 mediated NF-kB activation (2)
REACT_24969
Trafficking and processing of endosomal TLR (2)
REACT_118632
Trafficking of AMPA receptors (2)
REACT_18307
Trafficking of dietary sterols (3)
REACT_13781
Trafficking of GluR2-containing AMPA receptors (2)
REACT_18422
Transcriptional activation of mitochondrial biogenesis (4)
REACT_200608
Transcriptional regulation by small RNAs (1)
REACT_267668
Transcriptional regulation of white adipocyte differentiation (3)
REACT_27161
Transcription of the HIV genome (2)
REACT_6233
Transferrin endocytosis and recycling (2)
REACT_25283
Translation initiation complex formation (1)
REACT_1979
Translocation of GLUT4 to the plasma membrane (5)
REACT_147867
Translocation of ZAP-70 to Immunological synapse (2)
REACT_12596
Transport and synthesis of PAPS (4)
REACT_6840
Transport of fatty acids (2)
REACT_23892
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (3)
REACT_19305
Transport of glycerol from adipocytes to the liver by Aquaporins (1)
REACT_23809
Transport of inorganic cations/anions and amino acids/oligopeptides (4)
REACT_19397
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (16)
REACT_1206
Transport of nucleotide sugars (4)
REACT_22151
Transport of organic anions (9)
REACT_23988
Transport of vitamins, nucleosides, and related molecules (3)
REACT_22285
Triglyceride Biosynthesis (7)
REACT_1190
Tristetraprolin (TTP) destabilizes mRNA (2)
REACT_25064
TRKA activation by NGF (2)
REACT_11060
Tryptophan catabolism (14)
REACT_916
Ubiquinol biosynthesis (8)
REACT_160111
Ubiquitin-dependent degradation of Cyclin D1 (2)
REACT_4
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (2)
REACT_1614
Unblocking of NMDA receptor, glutamate binding and activation (2)
REACT_20594
Uptake and function of anthrax toxins (3)
REACT_228255
Urea cycle (15)
REACT_847
Utilization of Ketone Bodies (6)
REACT_59
Vasopressin regulates renal water homeostasis via Aquaporins (5)
REACT_24023
VEGFA-VEGFR2 Pathway (7)
REACT_228166
VEGFR2 mediated cell proliferation (5)
REACT_228024
VEGFR2 mediated vascular permeability (9)
REACT_228016
Vitamin B1 (thiamin) metabolism (5)
REACT_11117
Vitamin B2 (riboflavin) metabolism (6)
REACT_11070
Vitamin B5 (pantothenate) metabolism (1)
REACT_11172
Vitamin C (ascorbate) metabolism (5)
REACT_11202
Vitamin D (calciferol) metabolism (5)
REACT_13523
Vitamins (4)
REACT_13450
Vitamins B6 activation to pyridoxal phosphate (9)
REACT_25012
WNT5A-dependent internalization of FZD4 (2)
REACT_172599
WNT ligand biogenesis and trafficking (1)
REACT_163710
WNT mediated activation of DVL (2)
REACT_200668
Xenobiotics (3)
REACT_13543
YAP1- and WWTR1 (TAZ)-stimulated gene expression (2)
REACT_118713
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