ST001863 Analysis of Bxa induced metabolic changes in epithelial cells
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Abacavir metabolism (2) REACT_121388
Abnormal metabolism in phenylketonuria (3) REACT_121117
Acetylcholine Neurotransmitter Release Cycle (1) REACT_15309
Activation of AMPA receptors (1) REACT_18338
Activation of Ca-permeable Kainate Receptor (1) REACT_21346
Activation of Na-permeable Kainate Receptors (1) REACT_21343
Adenosine P1 receptors (1) REACT_18288
Adrenaline,noradrenaline inhibits insulin secretion (1) REACT_18339
Adrenaline signalling through Alpha-2 adrenergic receptor (1) REACT_19180
Adrenoceptors (1) REACT_16927
Aflatoxin activation and detoxification (2) REACT_228214
Agmatine biosynthesis (3) REACT_14800
Amino acid synthesis and interconversion (transamination) (6) REACT_238
Amino acid transport across the plasma membrane (22) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (18) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (18) REACT_75842
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (1) REACT_13721
Astrocytic Glutamate-Glutamine Uptake And Metabolism (2) REACT_13639
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (2) REACT_416
Biotin transport and metabolism (2) REACT_11153
Branched-chain amino acid catabolism (4) REACT_197
Carnitine synthesis (2) REACT_2125
Catecholamine biosynthesis (3) REACT_15551
Class C/3 (Metabotropic glutamate/pheromone receptors) (6) REACT_18319
Class II GLUTs (1) REACT_19281
Cleavage of the damaged purine (1) REACT_1729
Cobalamin (Cbl, vitamin B12) transport and metabolism (1) REACT_163862
Conjugation of benzoate with glycine (1) REACT_6933
Conjugation of phenylacetate with glutamine (1) REACT_6800
Conjugation of salicylate with glycine (1) REACT_6812
Creatine metabolism (5) REACT_813
CREB phosphorylation through the activation of CaMKII (2) REACT_20642
Cross-presentation of soluble exogenous antigens (endosomes) (18) REACT_111056
CYP2E1 reactions (1) REACT_13797
Cysteine formation from homocysteine (1) REACT_115589
Cytosolic sulfonation of small molecules (1) REACT_6913
Cytosolic tRNA aminoacylation (18) REACT_15306
Defective HLCS causes multiple carboxylase deficiency (1) REACT_169312
degradation of AXIN (1) REACT_200766
Degradation of cysteine and homocysteine (2) REACT_115654
Degradation of GABA (1) REACT_23964
Digestion of dietary lipid (1) REACT_9518
Downregulation of SMAD2/3:SMAD4 transcriptional activity (1) REACT_121111
Endosomal/Vacuolar pathway (18) REACT_111168
eNOS activation (2) REACT_12477
EPHB-mediated forward signaling (2) REACT_228085
ER-Phagosome pathway (18) REACT_111178
FMO oxidises nucleophiles (1) REACT_13653
GABA synthesis (1) REACT_24020
G alpha (12/13) signalling events (1) REACT_18407
G alpha (i) signalling events (7) REACT_19231
G alpha (q) signalling events (7) REACT_18283
G alpha (s) signalling events (4) REACT_19327
G alpha (z) signalling events (1) REACT_19333
Gluconeogenesis (2) REACT_1520
Glucuronidation (1) REACT_6784
Glutamate Neurotransmitter Release Cycle (2) REACT_12591
Glutathione synthesis and recycling (19) REACT_6960
Glyoxylate metabolism (2) REACT_16925
Heme biosynthesis (1) REACT_9465
Heme degradation (1) REACT_22297
Histamine receptors (1) REACT_16903
Histidine catabolism (4) REACT_1249
Hydrolysis of LPC (1) REACT_120977
Hypusine synthesis from eIF5A-lysine (1) REACT_12469
Import of palmitoyl-CoA into the mitochondrial matrix (1) REACT_11082
Inactivation, recovery and regulation of the phototransduction cascade (1) REACT_163919
Interconversion of polyamines (3) REACT_14805
Iron uptake and transport (1) REACT_25060
Ligand-gated ion channel transport (2) REACT_25387
Lysine catabolism (2) REACT_1298
Metabolism of folate and pterines (3) REACT_11167
Metabolism of polyamines (3) REACT_14820
Metabolism of serotonin (1) REACT_15532
Methionine salvage pathway (1) REACT_75881
Methylation (2) REACT_6946
Miscellaneous substrates (1) REACT_13425
Mitochondrial iron-sulfur cluster biogenesis (1) REACT_150353
Mitochondrial tRNA aminoacylation (18) REACT_15302
Molybdenum cofactor biosynthesis (2) REACT_25073
Na+/Cl- dependent neurotransmitter transporters (22) REACT_20506
Neurotransmitter Clearance In The Synaptic Cleft (1) REACT_13583
NGF-independant TRKA activation (1) REACT_11046
Nicotinamide salvaging (1) REACT_11213
Nicotinate metabolism (2) REACT_11088
Nitric oxide stimulates guanylate cyclase (2) REACT_23862
Organic anion transport (1) REACT_22310
Organic anion transporters (1) REACT_19372
Organic cation transport (8) REACT_22357
Orphan transporters (1) REACT_267716
PAOs oxidise polyamines to amines (3) REACT_505
Phagosomal maturation (early endosomal stage) (2) REACT_121256
Phenylalanine and tyrosine catabolism (4) REACT_1786
Platelet degranulation (1) REACT_318
Presynaptic function of Kainate receptors (1) REACT_21254
Proline catabolism (2) REACT_1002
Proton-coupled neutral amino acid transporters (3) REACT_19348
Proton/oligonucleotide cotransporters (18) REACT_19328
Purine catabolism (8) REACT_2086
Purine ribonucleoside monophosphate biosynthesis (3) REACT_1776
Purine salvage (6) REACT_1923
Pyrimidine biosynthesis (2) REACT_21376
Pyrimidine catabolism (3) REACT_1023
Pyrimidine salvage reactions (1) REACT_655
Ras activation uopn Ca2+ infux through NMDA receptor (2) REACT_20546
Recycling of bile acids and salts (3) REACT_11042
Regulation of HSF1-mediated heat shock response (1) REACT_200780
Regulation of thyroid hormone activity (1) REACT_15297
Reuptake of GABA (1) REACT_23910
Role of phospholipids in phagocytosis (1) REACT_160158
Serine biosynthesis (2) REACT_115789
Serotonin and melatonin biosynthesis (3) REACT_15439
Serotonin clearance from the synaptic cleft (1) REACT_15391
Serotonin Neurotransmitter Release Cycle (1) REACT_15425
Serotonin receptors (1) REACT_17064
SIRT1 negatively regulates rRNA Expression (1) REACT_200827
Sphingolipid de novo biosynthesis (2) REACT_115810
Stimuli-sensing channels (1) REACT_160189
Sulfur amino acid metabolism (6) REACT_115639
Synthesis and interconversion of nucleotide di- and triphosphates (2) REACT_21330
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (3) REACT_11041
Synthesis of Leukotrienes (LT) and Eoxins (EX) (2) REACT_150420
Synthesis of PA (1) REACT_120906
Synthesis of PC (1) REACT_121238
Synthesis of PG (1) REACT_121280
Synthesis of PS (2) REACT_120823
Synthesis of UDP-N-acetyl-glucosamine (2) REACT_22394
Synthesis, secretion, and deacylation of Ghrelin (1) REACT_19189
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1) REACT_111176
Thyroxine biosynthesis (3) REACT_15292
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (2) REACT_19305
Transport of inorganic cations/anions and amino acids/oligopeptides (2) REACT_19397
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (9) REACT_1206
Transport of organic anions (2) REACT_23988
Transport of vitamins, nucleosides, and related molecules (1) REACT_22285
Tryptophan catabolism (5) REACT_916
Unblocking of NMDA receptor, glutamate binding and activation (2) REACT_20594
Urea cycle (4) REACT_847
VEGFR2 mediated vascular permeability (2) REACT_228016
Vitamin B1 (thiamin) metabolism (1) REACT_11117
Vitamins B6 activation to pyridoxal phosphate (1) REACT_25012
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