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ST001928 Metabolomics profiles of premenopausal women are different based on O-desmethylangolensin metabotypeList of human metabolic pathways and metabolites (REACTOME)
Pathway name (# of metabolites detected in study)
Reactome pathway
Abacavir metabolism (1)
REACT_121388
Abnormal metabolism in phenylketonuria (4)
REACT_121117
Acetylation (1)
REACT_6732
Acetylcholine Neurotransmitter Release Cycle (1)
REACT_15309
Activation of AMPA receptors (1)
REACT_18338
Activation of Ca-permeable Kainate Receptor (1)
REACT_21346
Activation of G protein gated Potassium channels (1)
REACT_75831
Activation of Na-permeable Kainate Receptors (1)
REACT_21343
Aflatoxin activation and detoxification (2)
REACT_228214
Agmatine biosynthesis (3)
REACT_14800
Amine ligand-binding receptors (1)
REACT_16983
Amino acid synthesis and interconversion (transamination) (5)
REACT_238
Amino acid transport across the plasma membrane (20)
REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (15)
REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (15)
REACT_75842
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (1)
REACT_13721
Astrocytic Glutamate-Glutamine Uptake And Metabolism (2)
REACT_13639
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (1)
REACT_416
Biotin transport and metabolism (2)
REACT_11153
Branched-chain amino acid catabolism (2)
REACT_197
Carnitine synthesis (3)
REACT_2125
Catecholamine biosynthesis (4)
REACT_15551
Class C/3 (Metabotropic glutamate/pheromone receptors) (7)
REACT_18319
Cleavage of the damaged pyrimidine (1)
REACT_2156
Cobalamin (Cbl, vitamin B12) transport and metabolism (4)
REACT_163862
Coenzyme A biosynthesis (1)
REACT_11218
Condensation of Prophase Chromosomes (2)
REACT_172744
Conjugation of benzoate with glycine (2)
REACT_6933
Conjugation of phenylacetate with glutamine (2)
REACT_6800
Conjugation of salicylate with glycine (1)
REACT_6812
Creatine metabolism (8)
REACT_813
CREB phosphorylation through the activation of CaMKII (2)
REACT_20642
Cross-presentation of soluble exogenous antigens (endosomes) (15)
REACT_111056
CYP2E1 reactions (1)
REACT_13797
Cysteine formation from homocysteine (2)
REACT_115589
Cytosolic iron-sulfur cluster assembly (1)
REACT_160176
Cytosolic sulfonation of small molecules (2)
REACT_6913
Cytosolic tRNA aminoacylation (15)
REACT_15306
Defective HLCS causes multiple carboxylase deficiency (1)
REACT_169312
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG (1)
REACT_169149
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE (2)
REACT_169439
Degradation of cysteine and homocysteine (2)
REACT_115654
Degradation of GABA (2)
REACT_23964
Digestion of dietary carbohydrate (2)
REACT_9472
DNA methylation (2)
REACT_267652
Dopamine clearance from the synaptic cleft (1)
REACT_15514
Dopamine Neurotransmitter Release Cycle (1)
REACT_15293
Dopamine receptors (1)
REACT_16968
Endosomal/Vacuolar pathway (15)
REACT_111168
eNOS activation (3)
REACT_12477
Enzymatic degradation of dopamine by COMT (3)
REACT_15548
Enzymatic degradation of Dopamine by monoamine oxidase (2)
REACT_15511
EPHB-mediated forward signaling (2)
REACT_228085
ER-Phagosome pathway (15)
REACT_111178
FMO oxidises nucleophiles (1)
REACT_13653
formation of the beta-catenin:TCF transactivating complex (2)
REACT_200753
GABA A receptor activation (1)
REACT_24987
GABA A (rho) receptor activation (1)
REACT_25168
GABA B receptor activation (1)
REACT_25031
GABA synthesis (2)
REACT_24020
GABA synthesis, release, reuptake and degradation (1)
REACT_23947
G alpha (i) signalling events (4)
REACT_19231
G alpha (q) signalling events (4)
REACT_18283
G alpha (s) signalling events (2)
REACT_19327
Gluconeogenesis (3)
REACT_1520
Glucuronidation (2)
REACT_6784
Glutamate Neurotransmitter Release Cycle (2)
REACT_12591
Glutathione synthesis and recycling (16)
REACT_6960
Glyoxylate metabolism (2)
REACT_16925
Heme biosynthesis (1)
REACT_9465
Histidine catabolism (3)
REACT_1249
HS-GAG degradation (1)
REACT_120752
Hydrolysis of LPC (1)
REACT_120977
Hydrolysis of LPE (1)
REACT_120785
Inactivation, recovery and regulation of the phototransduction cascade (1)
REACT_163919
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (1)
REACT_25004
Interconversion of polyamines (1)
REACT_14805
Ligand-gated ion channel transport (2)
REACT_25387
Lysine catabolism (2)
REACT_1298
Meiotic recombination (2)
REACT_27271
Metabolism of folate and pterines (3)
REACT_11167
Metabolism of polyamines (4)
REACT_14820
Metabolism of serotonin (1)
REACT_15532
Methionine salvage pathway (3)
REACT_75881
Methylation (4)
REACT_6946
Mitochondrial tRNA aminoacylation (15)
REACT_15302
Molybdenum cofactor biosynthesis (2)
REACT_25073
mRNA Capping (2)
REACT_1470
Na+/Cl- dependent neurotransmitter transporters (18)
REACT_20506
Neurotransmitter Clearance In The Synaptic Cleft (1)
REACT_13583
Nicotinamide salvaging (1)
REACT_11213
Nicotinate metabolism (2)
REACT_11088
Nitric oxide stimulates guanylate cyclase (2)
REACT_23862
NoRC negatively regulates rRNA expression (2)
REACT_200856
Norepinephrine Neurotransmitter Release Cycle (1)
REACT_15418
NOSIP mediated eNOS trafficking (1)
REACT_12510
NOSTRIN mediated eNOS trafficking (1)
REACT_12541
Organic anion transporters (1)
REACT_19372
Organic cation transport (6)
REACT_22357
Orphan transporters (1)
REACT_267716
Oxidative Stress Induced Senescence (2)
REACT_169436
PAOs oxidise polyamines to amines (1)
REACT_505
Phagosomal maturation (early endosomal stage) (2)
REACT_121256
Phenylalanine and tyrosine catabolism (3)
REACT_1786
PRC2 methylates histones and DNA (2)
REACT_200808
Presynaptic function of Kainate receptors (1)
REACT_21254
Proline catabolism (2)
REACT_1002
Proton-coupled neutral amino acid transporters (2)
REACT_19348
Proton/oligonucleotide cotransporters (15)
REACT_19328
Purine catabolism (3)
REACT_2086
Purine ribonucleoside monophosphate biosynthesis (4)
REACT_1776
Purine salvage (4)
REACT_1923
Pyrimidine biosynthesis (4)
REACT_21376
Pyrimidine catabolism (4)
REACT_1023
Ras activation uopn Ca2+ infux through NMDA receptor (2)
REACT_20546
Recycling of bile acids and salts (2)
REACT_11042
Respiratory electron transport (1)
REACT_22393
Reuptake of GABA (3)
REACT_23910
RMTs methylate histone arginines (2)
REACT_228108
Role of phospholipids in phagocytosis (1)
REACT_160158
Senescence-Associated Secretory Phenotype (SASP) (2)
REACT_169168
Serine biosynthesis (2)
REACT_115789
Serotonin and melatonin biosynthesis (4)
REACT_15439
SIRT1 negatively regulates rRNA Expression (2)
REACT_200827
snRNP Assembly (1)
REACT_11066
Sphingolipid de novo biosynthesis (1)
REACT_115810
Sulfur amino acid metabolism (7)
REACT_115639
Synthesis and interconversion of nucleotide di- and triphosphates (2)
REACT_21330
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (2)
REACT_11041
Synthesis of Leukotrienes (LT) and Eoxins (EX) (2)
REACT_150420
Synthesis of PA (1)
REACT_120906
Synthesis of PC (3)
REACT_121238
Synthesis of PE (1)
REACT_120919
Synthesis of PG (1)
REACT_121280
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (1)
REACT_150149
Synthesis of PS (3)
REACT_120823
Synthesis of UDP-N-acetyl-glucosamine (2)
REACT_22394
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (2)
REACT_111176
Thyroxine biosynthesis (2)
REACT_15292
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (2)
REACT_19305
Transport of inorganic cations/anions and amino acids/oligopeptides (4)
REACT_19397
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (5)
REACT_1206
Transport of vitamins, nucleosides, and related molecules (1)
REACT_22285
Tryptophan catabolism (6)
REACT_916
Ubiquinol biosynthesis (3)
REACT_160111
Unblocking of NMDA receptor, glutamate binding and activation (2)
REACT_20594
Urea cycle (5)
REACT_847
VEGFR2 mediated vascular permeability (3)
REACT_228016
Vitamin B1 (thiamin) metabolism (1)
REACT_11117
Vitamin B2 (riboflavin) metabolism (1)
REACT_11070
Vitamins B6 activation to pyridoxal phosphate (4)
REACT_25012
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