ST001928 Metabolomics profiles of premenopausal women are different based on O-desmethylangolensin metabotype
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Abacavir metabolism (1) REACT_121388
Abnormal metabolism in phenylketonuria (4) REACT_121117
Acetylation (1) REACT_6732
Acetylcholine Neurotransmitter Release Cycle (1) REACT_15309
Activation of AMPA receptors (1) REACT_18338
Activation of Ca-permeable Kainate Receptor (1) REACT_21346
Activation of G protein gated Potassium channels (1) REACT_75831
Activation of Na-permeable Kainate Receptors (1) REACT_21343
Aflatoxin activation and detoxification (2) REACT_228214
Agmatine biosynthesis (3) REACT_14800
Amine ligand-binding receptors (1) REACT_16983
Amino acid synthesis and interconversion (transamination) (5) REACT_238
Amino acid transport across the plasma membrane (20) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (15) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (15) REACT_75842
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (1) REACT_13721
Astrocytic Glutamate-Glutamine Uptake And Metabolism (2) REACT_13639
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (1) REACT_416
Biotin transport and metabolism (2) REACT_11153
Branched-chain amino acid catabolism (2) REACT_197
Carnitine synthesis (3) REACT_2125
Catecholamine biosynthesis (4) REACT_15551
Class C/3 (Metabotropic glutamate/pheromone receptors) (7) REACT_18319
Cleavage of the damaged pyrimidine (1) REACT_2156
Cobalamin (Cbl, vitamin B12) transport and metabolism (4) REACT_163862
Coenzyme A biosynthesis (1) REACT_11218
Condensation of Prophase Chromosomes (2) REACT_172744
Conjugation of benzoate with glycine (2) REACT_6933
Conjugation of phenylacetate with glutamine (2) REACT_6800
Conjugation of salicylate with glycine (1) REACT_6812
Creatine metabolism (8) REACT_813
CREB phosphorylation through the activation of CaMKII (2) REACT_20642
Cross-presentation of soluble exogenous antigens (endosomes) (15) REACT_111056
CYP2E1 reactions (1) REACT_13797
Cysteine formation from homocysteine (2) REACT_115589
Cytosolic iron-sulfur cluster assembly (1) REACT_160176
Cytosolic sulfonation of small molecules (2) REACT_6913
Cytosolic tRNA aminoacylation (15) REACT_15306
Defective HLCS causes multiple carboxylase deficiency (1) REACT_169312
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG (1) REACT_169149
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE (2) REACT_169439
Degradation of cysteine and homocysteine (2) REACT_115654
Degradation of GABA (2) REACT_23964
Digestion of dietary carbohydrate (2) REACT_9472
DNA methylation (2) REACT_267652
Dopamine clearance from the synaptic cleft (1) REACT_15514
Dopamine Neurotransmitter Release Cycle (1) REACT_15293
Dopamine receptors (1) REACT_16968
Endosomal/Vacuolar pathway (15) REACT_111168
eNOS activation (3) REACT_12477
Enzymatic degradation of dopamine by COMT (3) REACT_15548
Enzymatic degradation of Dopamine by monoamine oxidase (2) REACT_15511
EPHB-mediated forward signaling (2) REACT_228085
ER-Phagosome pathway (15) REACT_111178
FMO oxidises nucleophiles (1) REACT_13653
formation of the beta-catenin:TCF transactivating complex (2) REACT_200753
GABA A receptor activation (1) REACT_24987
GABA A (rho) receptor activation (1) REACT_25168
GABA B receptor activation (1) REACT_25031
GABA synthesis (2) REACT_24020
GABA synthesis, release, reuptake and degradation (1) REACT_23947
G alpha (i) signalling events (4) REACT_19231
G alpha (q) signalling events (4) REACT_18283
G alpha (s) signalling events (2) REACT_19327
Gluconeogenesis (3) REACT_1520
Glucuronidation (2) REACT_6784
Glutamate Neurotransmitter Release Cycle (2) REACT_12591
Glutathione synthesis and recycling (16) REACT_6960
Glyoxylate metabolism (2) REACT_16925
Heme biosynthesis (1) REACT_9465
Histidine catabolism (3) REACT_1249
HS-GAG degradation (1) REACT_120752
Hydrolysis of LPC (1) REACT_120977
Hydrolysis of LPE (1) REACT_120785
Inactivation, recovery and regulation of the phototransduction cascade (1) REACT_163919
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (1) REACT_25004
Interconversion of polyamines (1) REACT_14805
Ligand-gated ion channel transport (2) REACT_25387
Lysine catabolism (2) REACT_1298
Meiotic recombination (2) REACT_27271
Metabolism of folate and pterines (3) REACT_11167
Metabolism of polyamines (4) REACT_14820
Metabolism of serotonin (1) REACT_15532
Methionine salvage pathway (3) REACT_75881
Methylation (4) REACT_6946
Mitochondrial tRNA aminoacylation (15) REACT_15302
Molybdenum cofactor biosynthesis (2) REACT_25073
mRNA Capping (2) REACT_1470
Na+/Cl- dependent neurotransmitter transporters (18) REACT_20506
Neurotransmitter Clearance In The Synaptic Cleft (1) REACT_13583
Nicotinamide salvaging (1) REACT_11213
Nicotinate metabolism (2) REACT_11088
Nitric oxide stimulates guanylate cyclase (2) REACT_23862
NoRC negatively regulates rRNA expression (2) REACT_200856
Norepinephrine Neurotransmitter Release Cycle (1) REACT_15418
NOSIP mediated eNOS trafficking (1) REACT_12510
NOSTRIN mediated eNOS trafficking (1) REACT_12541
Organic anion transporters (1) REACT_19372
Organic cation transport (6) REACT_22357
Orphan transporters (1) REACT_267716
Oxidative Stress Induced Senescence (2) REACT_169436
PAOs oxidise polyamines to amines (1) REACT_505
Phagosomal maturation (early endosomal stage) (2) REACT_121256
Phenylalanine and tyrosine catabolism (3) REACT_1786
PRC2 methylates histones and DNA (2) REACT_200808
Presynaptic function of Kainate receptors (1) REACT_21254
Proline catabolism (2) REACT_1002
Proton-coupled neutral amino acid transporters (2) REACT_19348
Proton/oligonucleotide cotransporters (15) REACT_19328
Purine catabolism (3) REACT_2086
Purine ribonucleoside monophosphate biosynthesis (4) REACT_1776
Purine salvage (4) REACT_1923
Pyrimidine biosynthesis (4) REACT_21376
Pyrimidine catabolism (4) REACT_1023
Ras activation uopn Ca2+ infux through NMDA receptor (2) REACT_20546
Recycling of bile acids and salts (2) REACT_11042
Respiratory electron transport (1) REACT_22393
Reuptake of GABA (3) REACT_23910
RMTs methylate histone arginines (2) REACT_228108
Role of phospholipids in phagocytosis (1) REACT_160158
Senescence-Associated Secretory Phenotype (SASP) (2) REACT_169168
Serine biosynthesis (2) REACT_115789
Serotonin and melatonin biosynthesis (4) REACT_15439
SIRT1 negatively regulates rRNA Expression (2) REACT_200827
snRNP Assembly (1) REACT_11066
Sphingolipid de novo biosynthesis (1) REACT_115810
Sulfur amino acid metabolism (7) REACT_115639
Synthesis and interconversion of nucleotide di- and triphosphates (2) REACT_21330
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (2) REACT_11041
Synthesis of Leukotrienes (LT) and Eoxins (EX) (2) REACT_150420
Synthesis of PA (1) REACT_120906
Synthesis of PC (3) REACT_121238
Synthesis of PE (1) REACT_120919
Synthesis of PG (1) REACT_121280
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (1) REACT_150149
Synthesis of PS (3) REACT_120823
Synthesis of UDP-N-acetyl-glucosamine (2) REACT_22394
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (2) REACT_111176
Thyroxine biosynthesis (2) REACT_15292
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (2) REACT_19305
Transport of inorganic cations/anions and amino acids/oligopeptides (4) REACT_19397
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (5) REACT_1206
Transport of vitamins, nucleosides, and related molecules (1) REACT_22285
Tryptophan catabolism (6) REACT_916
Ubiquinol biosynthesis (3) REACT_160111
Unblocking of NMDA receptor, glutamate binding and activation (2) REACT_20594
Urea cycle (5) REACT_847
VEGFR2 mediated vascular permeability (3) REACT_228016
Vitamin B1 (thiamin) metabolism (1) REACT_11117
Vitamin B2 (riboflavin) metabolism (1) REACT_11070
Vitamins B6 activation to pyridoxal phosphate (4) REACT_25012
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