Log in
/
Register
Home
Overview
Upload / Manage Data
Browse / Search Studies
Analyze Studies
Tutorials
FAQ
Data Repository
Overview
Upload / Manage Studies
Browse / Search Studies
Analyze Studies
Data Sharing Policy
Tutorials
FAQ
Databases
Overview
Metabolite Database
Human Metabolome Gene/Protein Database (MGP)
RefMet: Reference List of Metabolite Names
External Metabolomics Databases (Links)
Protocols
Overview
General Protocols
Study-specific Protocols
Tools
Overview
Load and analyze your own dataset
Analyze Studies
MS Searches
Structure drawing
REST Service
External Tools (Links)
About
Overview
Publishing Partners
How to Cite
How to Link
Terms of Use
Personnel
Contact
Sitemap
Search
Keyword Search
Advanced Searches
ST002301 Serum metabolomics profiling identifies new predictive biomarkers for disease severity in COVID-19 patientsList of human metabolic pathways and metabolites (REACTOME)
Pathway name (# of metabolites detected in study)
Reactome pathway
5-Phosphoribose 1-diphosphate biosynthesis (1)
REACT_850
Abacavir metabolism (2)
REACT_121388
ABH2 mediated Reversal of Alkylation Damage (1)
REACT_526
ABH3 mediated Reversal of Alkylation Damage (1)
REACT_1662
Abnormal metabolism in phenylketonuria (3)
REACT_121117
Acetylation (1)
REACT_6732
Activation of PPARGC1A (PGC-1alpha) by phosphorylation (1)
REACT_200686
Aflatoxin activation and detoxification (2)
REACT_228214
Agmatine biosynthesis (3)
REACT_14800
alpha-linolenic acid (ALA) metabolism (1)
REACT_121147
Alpha-oxidation of phytanate (2)
REACT_17003
Amino acid synthesis and interconversion (transamination) (5)
REACT_238
Amino acid transport across the plasma membrane (9)
REACT_13796
AMPK inhibits chREBP transcriptional activation activity (1)
REACT_1988
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (9)
REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (10)
REACT_75842
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (2)
REACT_13721
Astrocytic Glutamate-Glutamine Uptake And Metabolism (1)
REACT_13639
Beta-oxidation of pristanoyl-CoA (1)
REACT_17017
Beta-oxidation of very long chain fatty acids (1)
REACT_17062
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (1)
REACT_416
Biotin transport and metabolism (1)
REACT_11153
Branched-chain amino acid catabolism (2)
REACT_197
Cam-PDE 1 activation (1)
REACT_15408
Carnitine synthesis (2)
REACT_2125
Citric acid cycle (TCA cycle) (2)
REACT_1785
Class A/1 (Rhodopsin-like receptors) (1)
REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (3)
REACT_18319
Class II GLUTs (1)
REACT_19281
Cleavage of the damaged purine (1)
REACT_1729
Cobalamin (Cbl, vitamin B12) transport and metabolism (1)
REACT_163862
Coenzyme A biosynthesis (1)
REACT_11218
Collagen biosynthesis and modifying enzymes (1)
REACT_121139
Condensation of Prophase Chromosomes (1)
REACT_172744
Conjugation of benzoate with glycine (4)
REACT_6933
Conjugation of phenylacetate with glutamine (3)
REACT_6800
Conjugation of salicylate with glycine (2)
REACT_6812
Creatine metabolism (3)
REACT_813
CREB phosphorylation through the activation of CaMKII (1)
REACT_20642
Cross-presentation of soluble exogenous antigens (endosomes) (9)
REACT_111056
CYP2E1 reactions (1)
REACT_13797
Cysteine formation from homocysteine (1)
REACT_115589
Cytosolic sulfonation of small molecules (3)
REACT_6913
Cytosolic tRNA aminoacylation (10)
REACT_15306
DARPP-32 events (1)
REACT_15334
Deadenylation of mRNA (1)
REACT_20514
degradation of AXIN (1)
REACT_200766
Degradation of cysteine and homocysteine (1)
REACT_115654
Degradation of GABA (2)
REACT_23964
Digestion of dietary lipid (1)
REACT_9518
Downregulation of SMAD2/3:SMAD4 transcriptional activity (1)
REACT_121111
Endogenous sterols (1)
REACT_13812
Endosomal/Vacuolar pathway (9)
REACT_111168
eNOS activation (1)
REACT_12477
EPHB-mediated forward signaling (1)
REACT_228085
ER-Phagosome pathway (9)
REACT_111178
Ethanol oxidation (2)
REACT_34
Factors involved in megakaryocyte development and platelet production (1)
REACT_24970
Fatty Acyl-CoA Biosynthesis (1)
REACT_1319
FCERI mediated NF-kB activation (1)
REACT_163994
FMO oxidises nucleophiles (1)
REACT_13653
Free fatty acid receptors (2)
REACT_21268
GABA synthesis (1)
REACT_24020
G alpha (i) signalling events (3)
REACT_19231
G alpha (q) signalling events (3)
REACT_18283
G alpha (s) signalling events (2)
REACT_19327
Glucocorticoid biosynthesis (1)
REACT_11036
Gluconeogenesis (3)
REACT_1520
Glucuronidation (2)
REACT_6784
Glutamate Neurotransmitter Release Cycle (1)
REACT_12591
Glutathione synthesis and recycling (10)
REACT_6960
Glycogen breakdown (glycogenolysis) (1)
REACT_1008
Glycolysis (1)
REACT_1383
Glycosphingolipid metabolism (1)
REACT_116105
Glyoxylate metabolism (1)
REACT_16925
HDMs demethylate histones (1)
REACT_228178
Heme biosynthesis (1)
REACT_9465
Histidine catabolism (2)
REACT_1249
HS-GAG biosynthesis (1)
REACT_121248
Hydrolysis of LPE (1)
REACT_120785
Inactivation, recovery and regulation of the phototransduction cascade (1)
REACT_163919
ISG15 antiviral mechanism (1)
REACT_115831
Ligand-gated ion channel transport (2)
REACT_25387
Linoleic acid (LA) metabolism (1)
REACT_121100
Metabolism of folate and pterines (1)
REACT_11167
Metabolism of nucleotides (1)
REACT_1698
Metabolism of serotonin (2)
REACT_15532
Methionine salvage pathway (2)
REACT_75881
Methylation (1)
REACT_6946
Miscellaneous substrates (1)
REACT_13425
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) (1)
REACT_228019
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (1)
REACT_228145
Mitochondrial iron-sulfur cluster biogenesis (1)
REACT_150353
Mitochondrial tRNA aminoacylation (10)
REACT_15302
Molybdenum cofactor biosynthesis (3)
REACT_25073
mRNA decay by 3' to 5' exoribonuclease (1)
REACT_20619
mRNA decay by 5' to 3' exoribonuclease (1)
REACT_20518
Na+/Cl- dependent neurotransmitter transporters (10)
REACT_20506
Nicotinamide salvaging (1)
REACT_11213
Nicotinate metabolism (2)
REACT_11088
Nitric oxide stimulates guanylate cyclase (1)
REACT_23862
NoRC negatively regulates rRNA expression (1)
REACT_200856
Organic anion transport (1)
REACT_22310
Organic anion transporters (1)
REACT_19372
Organic cation transport (2)
REACT_22357
Orphan transporters (1)
REACT_267716
Oxidative Stress Induced Senescence (1)
REACT_169436
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha (1)
REACT_121226
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (1)
REACT_120916
Passive transport by Aquaporins (1)
REACT_23826
PDE3B signalling (1)
REACT_1451
Phagosomal maturation (early endosomal stage) (1)
REACT_121256
Phenylalanine and tyrosine catabolism (1)
REACT_1786
Phosphate bond hydrolysis by NUDT proteins (2)
REACT_150237
Platelet degranulation (1)
REACT_318
Proline catabolism (1)
REACT_1002
Proton-coupled neutral amino acid transporters (2)
REACT_19348
Proton/oligonucleotide cotransporters (9)
REACT_19328
Purine catabolism (4)
REACT_2086
Purine ribonucleoside monophosphate biosynthesis (4)
REACT_1776
Purine salvage (3)
REACT_1923
Pyrimidine biosynthesis (1)
REACT_21376
Pyrimidine catabolism (1)
REACT_1023
Pyrimidine salvage reactions (1)
REACT_655
Ras activation uopn Ca2+ infux through NMDA receptor (1)
REACT_20546
Recycling of bile acids and salts (3)
REACT_11042
Regulation of AMPK activity via LKB1 (1)
REACT_21285
Regulation of HSF1-mediated heat shock response (1)
REACT_200780
Regulation of ornithine decarboxylase (ODC) (1)
REACT_13565
Regulation of Rheb GTPase activity by AMPK (1)
REACT_21393
Regulation of thyroid hormone activity (1)
REACT_15297
Removal of the Flap Intermediate (1)
REACT_70
Removal of the Flap Intermediate from the C-strand (1)
REACT_7999
Respiratory electron transport (1)
REACT_22393
Scavenging by Class A Receptors (1)
REACT_163699
Serine biosynthesis (1)
REACT_115789
Serotonin and melatonin biosynthesis (4)
REACT_15439
Serotonin clearance from the synaptic cleft (1)
REACT_15391
Serotonin Neurotransmitter Release Cycle (1)
REACT_15425
Serotonin receptors (1)
REACT_17064
SIRT1 negatively regulates rRNA Expression (1)
REACT_200827
Sodium-coupled sulphate, di- and tri-carboxylate transporters (1)
REACT_20646
Sphingolipid de novo biosynthesis (1)
REACT_115810
Stimuli-sensing channels (2)
REACT_160189
Sulfur amino acid metabolism (2)
REACT_115639
SUMO is conjugated to E1 (UBA2:SAE1) (1)
REACT_163812
Synthesis and interconversion of nucleotide di- and triphosphates (2)
REACT_21330
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (1)
REACT_11053
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (3)
REACT_11041
Synthesis of glycosylphosphatidylinositol (GPI) (1)
REACT_952
Synthesis of Leukotrienes (LT) and Eoxins (EX) (1)
REACT_150420
Synthesis of PE (1)
REACT_120919
Synthesis of PS (1)
REACT_120823
Synthesis of UDP-N-acetyl-glucosamine (1)
REACT_22394
Synthesis of very long-chain fatty acyl-CoAs (1)
REACT_380
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (1)
REACT_24019
TET1,2,3 and TDG demethylate DNA (1)
REACT_200682
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1)
REACT_111176
Thyroxine biosynthesis (1)
REACT_15292
Translocation of GLUT4 to the plasma membrane (1)
REACT_147867
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (1)
REACT_19305
Transport of inorganic cations/anions and amino acids/oligopeptides (1)
REACT_19397
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (4)
REACT_1206
Transport of organic anions (2)
REACT_23988
Tryptophan catabolism (4)
REACT_916
Unblocking of NMDA receptor, glutamate binding and activation (1)
REACT_20594
Urea cycle (3)
REACT_847
Utilization of Ketone Bodies (1)
REACT_59
VEGFR2 mediated cell proliferation (1)
REACT_228024
VEGFR2 mediated vascular permeability (1)
REACT_228016
Vitamin B1 (thiamin) metabolism (1)
REACT_11117
Vitamin B2 (riboflavin) metabolism (1)
REACT_11070
Vitamins B6 activation to pyridoxal phosphate (1)
REACT_25012
Xenobiotics (1)
REACT_13543
Metabolomics Workbench
Terms of use
Site map
Contact