ST002419 Metabolomic changes in growth of E. colik at four timespoints in MOPS rich and minimum medium
List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Abacavir metabolism (2) REACT_121388
ABH2 mediated Reversal of Alkylation Damage (1) REACT_526
ABH3 mediated Reversal of Alkylation Damage (1) REACT_1662
Abnormal metabolism in phenylketonuria (4) REACT_121117
Activation of AMPA receptors (1) REACT_18338
Activation of Ca-permeable Kainate Receptor (1) REACT_21346
Activation of G protein gated Potassium channels (1) REACT_75831
Activation of Na-permeable Kainate Receptors (1) REACT_21343
Adenosine P1 receptors (1) REACT_18288
Adenylate cyclase activating pathway (1) REACT_15312
Aflatoxin activation and detoxification (3) REACT_228214
Agmatine biosynthesis (2) REACT_14800
alpha-linolenic acid (ALA) metabolism (1) REACT_121147
Alpha-oxidation of phytanate (2) REACT_17003
Amino acid synthesis and interconversion (transamination) (8) REACT_238
Amino acid transport across the plasma membrane (20) REACT_13796
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (18) REACT_75795
Antigen processing: Ubiquitination & Proteasome degradation (19) REACT_75842
Astrocytic Glutamate-Glutamine Uptake And Metabolism (2) REACT_13639
Biotin transport and metabolism (2) REACT_11153
Branched-chain amino acid catabolism (5) REACT_197
Carnitine synthesis (2) REACT_2125
Catecholamine biosynthesis (1) REACT_15551
Cholesterol biosynthesis (1) REACT_9405
Citric acid cycle (TCA cycle) (4) REACT_1785
Class A/1 (Rhodopsin-like receptors) (3) REACT_14828
Class C/3 (Metabotropic glutamate/pheromone receptors) (4) REACT_18319
Cleavage of the damaged pyrimidine (2) REACT_2156
Cobalamin (Cbl, vitamin B12) transport and metabolism (1) REACT_163862
Coenzyme A biosynthesis (2) REACT_11218
Collagen biosynthesis and modifying enzymes (1) REACT_121139
Condensation of Prophase Chromosomes (1) REACT_172744
Conjugation of benzoate with glycine (3) REACT_6933
Conjugation of phenylacetate with glutamine (2) REACT_6800
Conjugation of salicylate with glycine (2) REACT_6812
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (1) REACT_6867
Creatine metabolism (2) REACT_813
CREB phosphorylation through the activation of Adenylate Cyclase (1) REACT_20625
CREB phosphorylation through the activation of CaMKII (2) REACT_20642
Cross-presentation of soluble exogenous antigens (endosomes) (18) REACT_111056
Cysteine formation from homocysteine (2) REACT_115589
Cytosolic tRNA aminoacylation (19) REACT_15306
degradation of AXIN (1) REACT_200766
Degradation of cysteine and homocysteine (2) REACT_115654
Degradation of GABA (3) REACT_23964
Detoxification of Reactive Oxygen Species (1) REACT_172715
Digestion of dietary carbohydrate (2) REACT_9472
Downregulation of SMAD2/3:SMAD4 transcriptional activity (1) REACT_121111
Downstream TCR signaling (1) REACT_12555
Endosomal/Vacuolar pathway (18) REACT_111168
eNOS activation (1) REACT_12477
EPHB-mediated forward signaling (2) REACT_228085
ER-Phagosome pathway (18) REACT_111178
Ethanol oxidation (1) REACT_34
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (1) REACT_19193
Fatty acid, triacylglycerol, and ketone body metabolism (1) REACT_22279
Fatty Acyl-CoA Biosynthesis (2) REACT_1319
FCERI mediated NF-kB activation (1) REACT_163994
Formation of the active cofactor, UDP-glucuronate (1) REACT_6737
Free fatty acid receptors (3) REACT_21268
GABA A receptor activation (1) REACT_24987
GABA A (rho) receptor activation (1) REACT_25168
GABA B receptor activation (1) REACT_25031
GABA synthesis (2) REACT_24020
GABA synthesis, release, reuptake and degradation (1) REACT_23947
G alpha (i) signalling events (8) REACT_19231
G alpha (q) signalling events (4) REACT_18283
G alpha (s) signalling events (2) REACT_19327
G alpha (z) signalling events (1) REACT_19333
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (1) REACT_18274
Gluconeogenesis (4) REACT_1520
Glutamate Neurotransmitter Release Cycle (2) REACT_12591
Glutathione conjugation (1) REACT_6926
Glutathione synthesis and recycling (20) REACT_6960
Glycogen synthesis (1) REACT_169208
Glycolysis (1) REACT_1383
Glyoxylate metabolism (4) REACT_16925
HDMs demethylate histones (1) REACT_228178
Hedgehog 'off' state (1) REACT_267634
Heme biosynthesis (2) REACT_9465
Histidine catabolism (1) REACT_1249
HIV Transcription Initiation (1) REACT_6332
HS-GAG degradation (1) REACT_120752
Hydrolysis of LPC (1) REACT_120977
Hydrolysis of LPE (1) REACT_120785
Hydroxycarboxylic acid-binding receptors (3) REACT_163785
Inactivation, recovery and regulation of the phototransduction cascade (2) REACT_163919
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (1) REACT_25004
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (1) REACT_25367
Interconversion of polyamines (1) REACT_14805
ISG15 antiviral mechanism (1) REACT_115831
Keratan sulfate biosynthesis (1) REACT_121120
Ligand-gated ion channel transport (2) REACT_25387
Linoleic acid (LA) metabolism (1) REACT_121100
Lysine catabolism (2) REACT_1298
Metabolism of folate and pterines (3) REACT_11167
Metabolism of nucleotides (1) REACT_1698
Metabolism of polyamines (3) REACT_14820
Methionine salvage pathway (3) REACT_75881
Methylation (3) REACT_6946
Minus-strand DNA synthesis (1) REACT_9055
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) (1) REACT_228019
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (1) REACT_228145
Mitochondrial iron-sulfur cluster biogenesis (2) REACT_150353
Mitochondrial tRNA aminoacylation (19) REACT_15302
Molybdenum cofactor biosynthesis (4) REACT_25073
mRNA decay by 3' to 5' exoribonuclease (1) REACT_20619
mRNA decay by 5' to 3' exoribonuclease (1) REACT_20518
Na+/Cl- dependent neurotransmitter transporters (18) REACT_20506
NGF-independant TRKA activation (1) REACT_11046
Nicotinamide salvaging (3) REACT_11213
Nicotinate metabolism (3) REACT_11088
Nitric oxide stimulates guanylate cyclase (2) REACT_23862
Organic anion transport (1) REACT_22310
Organic anion transporters (3) REACT_19372
Orphan transporters (1) REACT_267716
Oxidative Stress Induced Senescence (1) REACT_169436
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_121226
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (1) REACT_120916
PAOs oxidise polyamines to amines (1) REACT_505
Passive transport by Aquaporins (1) REACT_23826
PD-1 signaling (1) REACT_19324
Pentose phosphate pathway (hexose monophosphate shunt) (1) REACT_1859
Phagosomal maturation (early endosomal stage) (2) REACT_121256
Phenylalanine and tyrosine catabolism (5) REACT_1786
Phosphate bond hydrolysis by NUDT proteins (1) REACT_150237
PKA activation (1) REACT_15530
PKA activation in glucagon signalling (1) REACT_1946
Platelet degranulation (1) REACT_318
Pre-NOTCH Processing in Golgi (1) REACT_118798
Presynaptic function of Kainate receptors (1) REACT_21254
Proline catabolism (2) REACT_1002
Proton-coupled monocarboxylate transport (1) REACT_20515
Proton-coupled neutral amino acid transporters (3) REACT_19348
Proton/oligonucleotide cotransporters (18) REACT_19328
Purine catabolism (5) REACT_2086
Purine ribonucleoside monophosphate biosynthesis (5) REACT_1776
Purine salvage (5) REACT_1923
Pyrimidine biosynthesis (5) REACT_21376
Pyrimidine catabolism (6) REACT_1023
Pyrimidine salvage reactions (4) REACT_655
Pyruvate metabolism (1) REACT_2071
Rap1 signalling (1) REACT_23898
Ras activation uopn Ca2+ infux through NMDA receptor (2) REACT_20546
Recycling of bile acids and salts (2) REACT_11042
Regulation of HSF1-mediated heat shock response (1) REACT_200780
Removal of DNA patch containing abasic residue (1) REACT_2192
Removal of the Flap Intermediate (1) REACT_70
Removal of the Flap Intermediate from the C-strand (1) REACT_7999
Resolution of AP sites via the single-nucleotide replacement pathway (1) REACT_933
Retinoid metabolism and transport (1) REACT_24968
Reuptake of GABA (2) REACT_23910
RNA Polymerase II HIV Promoter Escape (1) REACT_6253
RNA Polymerase II Promoter Escape (1) REACT_2089
RNA Polymerase II Transcription Initiation (1) REACT_1851
Scavenging by Class A Receptors (1) REACT_163699
Serine biosynthesis (2) REACT_115789
Serotonin and melatonin biosynthesis (1) REACT_15439
Sialic acid metabolism (2) REACT_200874
SIRT1 negatively regulates rRNA Expression (1) REACT_200827
Sodium-coupled sulphate, di- and tri-carboxylate transporters (2) REACT_20646
Sphingolipid de novo biosynthesis (1) REACT_115810
Stimuli-sensing channels (1) REACT_160189
STING mediated induction of host immune responses (1) REACT_147841
Sulfide oxidation to sulfate (2) REACT_116010
Sulfur amino acid metabolism (6) REACT_115639
SUMO is conjugated to E1 (UBA2:SAE1) (1) REACT_163812
Synthesis and interconversion of nucleotide di- and triphosphates (4) REACT_21330
Synthesis of 12-eicosatetraenoic acid derivatives (1) REACT_150201
Synthesis of 15-eicosatetraenoic acid derivatives (1) REACT_150422
Synthesis of 5-eicosatetraenoic acids (1) REACT_150209
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (1) REACT_11053
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (2) REACT_11041
Synthesis of CL (1) REACT_120920
Synthesis of Dolichyl-phosphate (1) REACT_22230
Synthesis of GDP-mannose (1) REACT_22423
Synthesis of IP2, IP, and Ins in the cytosol (1) REACT_150352
Synthesis of Leukotrienes (LT) and Eoxins (EX) (3) REACT_150420
Synthesis of PA (1) REACT_120906
Synthesis of PC (2) REACT_121238
Synthesis of PE (2) REACT_120919
Synthesis of PG (3) REACT_121280
Synthesis of PI (2) REACT_121000
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (1) REACT_150149
Synthesis of PS (1) REACT_120823
Synthesis of UDP-N-acetyl-glucosamine (3) REACT_22394
Synthesis of very long-chain fatty acyl-CoAs (1) REACT_380
Synthesis, secretion, and deacylation of Ghrelin (2) REACT_19189
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (3) REACT_24019
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (1) REACT_23824
Termination of O-glycan biosynthesis (1) REACT_115835
TET1,2,3 and TDG demethylate DNA (1) REACT_200682
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1) REACT_111176
The canonical retinoid cycle in rods (twilight vision) (1) REACT_160156
Thyroxine biosynthesis (2) REACT_15292
Transport and synthesis of PAPS (1) REACT_6840
Transport of fatty acids (3) REACT_23892
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds (1) REACT_19305
Transport of inorganic cations/anions and amino acids/oligopeptides (4) REACT_19397
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (8) REACT_1206
Transport of nucleotide sugars (1) REACT_22151
Triglyceride Biosynthesis (1) REACT_1190
Tryptophan catabolism (4) REACT_916
Ubiquinol biosynthesis (2) REACT_160111
Unblocking of NMDA receptor, glutamate binding and activation (2) REACT_20594
Uptake and function of anthrax toxins (1) REACT_228255
Urea cycle (6) REACT_847
Utilization of Ketone Bodies (1) REACT_59
Vasopressin regulates renal water homeostasis via Aquaporins (1) REACT_24023
VEGFR2 mediated vascular permeability (1) REACT_228016
Vitamin B2 (riboflavin) metabolism (1) REACT_11070
Vitamin C (ascorbate) metabolism (1) REACT_11202
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