List of Studies ( Metabolite:1-Pyrroline-5-carboxylic acid)
Study_id | Analysis_id | Study_title | Source | Species | Disease | Institute | Units(range) |
---|---|---|---|---|---|---|---|
ST001680 | AN002739 | Metabolome of NAFLD in high fat diet mouse model | Liver | Mouse | Fatty liver disease | Weill Cornell Medicine | Abundance |
ST000450 | AN000705 | Metabolic features of chronic fatigue syndrome | Blood | Human | Myalgic encephalomyelitis/chronic fatigue syndrome | University of California, San Diego | Area under curve |
ST000465 | AN000727 | Uniquely Tumor-Selective Englerin A Profoundly Alters Lipid Metabolism in Renal Cell Carcinoma inducing ER-Stress and an Acute Inflammatory Response | Kidney | Human | Cancer | University of California, San Diego | Area under curve |
ST000617 | AN000947 | Validation of the application of targeted metabolomic appraoch in the diagnosis of CFS | Blood | Human | Myalgic encephalomyelitis/chronic fatigue syndrome | University of California, San Diego | Area under curve |
ST000903 | AN001469 | Pharmacometabolomic analysis of rat hippocampus and plasma in response to chronic stress and albiflorin treament | Blood | Rat | Stress | Beijing Woner Biotech Co. Ltd | Area under curve |
ST001639 | AN002681 | Plasma Metabolomic signatures of COPD in a SPIROMICS cohort | Blood | Human | COPD | National Jewish Health | AU |
ST003546 | AN005825 | Improved Soil Health and Pasture Phytochemical Richness Underlies Improved Beef Nutrient Density in Southern US Grass-Finished Beef Systems | Muscle | Cattle | Utah State University | AU | |
ST001855 | AN003006 | The metabolomic resetting effect of FG4592 in AKI to CKD transition-day 21 (Part 1) | Kidney | Mouse | Kidney disease | Children’s Hospital of Nanjing Medical University | AUC |
ST002373 | AN003868 | Extracellular metabolome of activated CD8+ T cells | Cultured cells | Mouse | Johns Hopkins University | AUC | |
ST002374 | AN003869 | Metabolomics analysis of WT vs. GOT1 knockout CD8+ T cells | Cultured cells | Mouse | Johns Hopkins University | AUC | |
ST002375 | AN003870 | Metabolomics analysis of WT or GOT1 knockout CD8+ T cells cultured in serine-replete or serine-free media | Cultured cells | Mouse | Johns Hopkins University | AUC | |
ST001403 | AN002345 | Ontogeny related changes in the pediatric liver metabolome (part-II) | Liver | Human | Moffitt Cancer Center | estimated abundances | |
ST002555 | AN004207 | Ethnicity-Specific Differences in Ovarian Cancer Metabolic Signatures | Cultured cells | Human | Cancer | University of Oklahoma Health Sciences Center | Fold change over standard |
ST002155 | AN003530 | Longitudinal metabolomic stool dynamics in primary C. difficile infections | Feces | Human | Bacterial infection | Brigham Women's Hospital | intensity |
ST001788 | AN002899 | β-Adrenergic regulation of metabolism in macrophages (part-IV) | Macrophages | Human | Monash University | Intensity | |
ST001788 | AN002900 | β-Adrenergic regulation of metabolism in macrophages (part-IV) | Macrophages | Human | Monash University | Intensity | |
ST002010 | AN003276 | Chemoresistant Ovarian Cancer Global Metabolomics | Cultured cells | Human | Cancer | The University of South Australia | Intensity |
ST001775 | AN002882 | Plasma metabolomics of diverse mouse strains infected with Plasmodium chabaudi | Blood | Mouse | Malaria | Stanford University | ion counts |
ST002829 | AN004619 | Nucleotide, phospholipid, and kynurenine metabolites are robustly associated with COVID-19 severity and time of plasma sample collection in a prospective cohort study | Blood | Human | COVID-19 | National Institutes of Health | log transformed data |
ST001940 | AN003155 | Cognitive Behavioral Therapy for Irritable Bowel Syndrome Induces Bidirectional Alterations in the Brain-Gut-Microbiome Axis Associated with Gastrointestinal Symptom Improvement | Feces | Human | Irritable bowel syndrome | University of California, Los Angeles | Metabolon original scale |
ST001940 | AN003156 | Cognitive Behavioral Therapy for Irritable Bowel Syndrome Induces Bidirectional Alterations in the Brain-Gut-Microbiome Axis Associated with Gastrointestinal Symptom Improvement | Feces | Human | Irritable bowel syndrome | University of California, Los Angeles | Metabolon original scale |
ST001940 | AN003157 | Cognitive Behavioral Therapy for Irritable Bowel Syndrome Induces Bidirectional Alterations in the Brain-Gut-Microbiome Axis Associated with Gastrointestinal Symptom Improvement | Feces | Human | Irritable bowel syndrome | University of California, Los Angeles | Metabolon original scale |
ST001940 | AN003158 | Cognitive Behavioral Therapy for Irritable Bowel Syndrome Induces Bidirectional Alterations in the Brain-Gut-Microbiome Axis Associated with Gastrointestinal Symptom Improvement | Feces | Human | Irritable bowel syndrome | University of California, Los Angeles | Metabolon original scale |
ST002322 | AN003789 | Metabolomics study comparing SCAP KO and WT B cells | Cultured cells | Mouse | Indiana University School of Medicine | Normalized AUC | |
ST003277 | AN005365 | LC-MS/MS spatial analysis of mouse GI | Intestine | Mouse | Brown University | normalized imputed data | |
ST002809 | AN004566 | Role of cilia in mitochondrial function | Cultured cells | Dog | Kidney disease | Medical University of South Carolina | Normalized/scaled raw area counts |
ST002809 | AN004566 | Role of cilia in mitochondrial function | Cultured cells | Mouse | Kidney disease | Medical University of South Carolina | Normalized/scaled raw area counts |
ST002020 | AN003290 | TIPs Metabolomics (urine) | Urine | Human | Vanderbilt University Medical Center | osmolality normalized scaled imputed | |
ST001780 | AN002890 | Comparative analysis of metabolomic profiles in cerebrospinal fluid before and after endurance exercise | Cerebrospinal fluid | Human | UCSD School of Medicine | peak area | |
ST001789 | AN002901 | Acute metabolomic changes of plasma in response to endurance exercise | Blood | Human | University of California, San Diego | peak area | |
ST002498 | AN004654 | Plasma Metabolomics Profiling of 580 Patients from the Weill Cornell Medicine Early Detection Research Network Prostate Cancer Cohort | Blood | Human | Cancer | Weill Cornell Medicine | peak area |
ST000230 | AN000344 | Comprehensive analysis of transcriptome and metabolome in Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma | Liver | Human | Cancer | Osaka City University | Peak area |
ST000922 | AN001511 | Crab Urine Study | Urine | Crab | Georgia Institute of Technology | Peak area | |
ST001158 | AN001916 | The gut microbiota plays a central role to modulate the plasma metabolome in response to chronic Angiotensin II infusion (part-II) | Feces | Mouse | Johns Hopkins University School of Medicine | Peak area | |
ST001212 | AN002045 | Fish-oil supplementation in pregnancy, child metabolomics and asthma risk | Blood | Human | Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen | Peak area | |
ST001411 | AN002361 | Plasma metabolites of lipid metabolism associate with diabetic polyneuropathy in a cohort with screen-tested type 2 diabetes: ADDITION-Denmark | Blood | Human | Obesity | University of Michigan | Peak area |
ST001412 | AN002362 | Metabolomics study in Plasma of Obese Patients with Neuropathy Identifies Potential Metabolomics Signatures | Blood | Human | Obesity | University of Michigan | Peak area |
ST001420 | AN002375 | Metabolomic analysis of patients with recurrent angina | Blood | Human | Angina | University of California, San Diego | Peak area |
ST002376 | AN003871 | Hepatic Phosphatidylcholine Catabolism Driven by PNPLA7 and PNPLA8 Supplies Endogenous Choline to Replenish the Methionine Cycle with Methyl Groups(Pnpla8-knockout) | Liver | Mouse | Tokyo Metropolitan Institute of Medical Science | Peak area | |
ST002909 | AN004775 | Plasma metabolomics reveals distinct biological and diagnostic signatures for melioidosis | Blood | Human | Melioidosis | University of Washington | Peak area |
ST003178 | AN005217 | Post-Infectious MECFS at the NIH | Cerebrospinal fluid | Human | Chronic fatigue syndrome | National Institutes of Health | Peak area |
ST003333 | AN005460 | Urine Metabolite Profiling in Indian Male Population at High Altitude using Liquid Chromatography – Mass Spectrometry: A Longitudinal Pilot Study | Urine | Human | Environmental exposure; Hypoxia | Defence Institute of Physiology and Allied Sceinces | Peak area |
ST003348 | AN005483 | An integrated LC-MS analysis of the biometric characteristics of different time cohorts of race walkers - untargeted | Blood | Human | The First Affiliated Hospital of Dalian Medical University | Peak area | |
ST003520 | AN005778 | Identification of Plasma Metabolomic Biomarkers of Juvenile Idiopathic Arthritis | Blood | Human | Arthritis | University of Kansas | Peak area |
ST002754 | AN004468 | Metabolomics analysis of maternal obesity model | Blood | Mouse | Fatty liver disease | University of Bonn | Peak Area |
ST002066 | AN003366 | Glutaminase inhibition impairs CD8 T cell activation in STK11/Lkb1 deficient lung cancer | Lung | Mouse | Cancer | The Walter and Eliza Hall Institute of Medical Research | peak height |
ST002104 | AN003440 | Chemoresistant Cancer Cell Lines are Characterized by Migratory, Amino Acid Metabolism, Protein Catabolism and IFN1 Signalling Perturbations | Cultured cells | Human | Cancer | Future Industries Institute | peak height |
ST002412 | AN003931 | Metabolic effects of the protein kinase R | Macrophages | Mouse | Hudson | peak height | |
ST002792 | AN004543 | Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as a cross-species strategy to treat malaria | Blood | Plasmodium falciparum | Malaria | Monash University | peak height |
ST003053 | AN005006 | Providing insight into the mechanism of action of Cationic Lipidated Oligomers (CLOs) using metabolomics | Bacterial cells | Staphylococcus aureus | Bacterial infection | Monash University | peak height |
ST003053 | AN005007 | Providing insight into the mechanism of action of Cationic Lipidated Oligomers (CLOs) using metabolomics | Bacterial cells | Staphylococcus aureus | Bacterial infection | Monash University | peak height |
ST003144 | AN005160 | On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity | Blood | Plasmodium falciparum | Malaria | Monash University | peak height |
ST003521 | AN005782 | Metabolic Profiling Unveils Enhanced Antibacterial Synergy of Polymyxin B and Teixobactin against Multi-Drug Resistant Acinetobacter baumannii | Bacterial cells | Acinetobacter baumannii | Bacterial infection | Monash University | peak height |
ST000403 | AN000643 | Metabolomics-based elucidation of active metabolic pathways in erythrocytes and HSC-derived reticulocytes | Cells | Human | Monash Institute of Pharmaceutical Sciences, Monash University | Peak height | |
ST000414 | AN000655 | Metabolomics-based screening of the Malaria Box reveals both novel and established mechanisms of action | Cells | Plasmodium falciparum | Malaria | Monash Institute of Pharmaceutical Sciences, Monash University | Peak height |
ST000539 | AN000819 | Metabolomics-based elucidation of active metabolic pathways in erythrocytes and HSC-derived reticulocytes (part II) | Cells | Human | Monash Institute of Pharmaceutical Sciences, Monash University | Peak height | |
ST000546 | AN000832 | Multi-omics based identification of specific biochemical changes associated with PfKelch13-mutant artemisinin resistant Plasmodium | Cells | Plasmodium falciparum | Malaria | Monash Institute of Pharmaceutical Sciences, Monash University | Peak height |
ST001033 | AN001694 | Determination of mode of action of anti-malalrial drugs using untargeted metabolomics | Cultured cells | Plasmodium falciparum | Malaria | Monash University | Peak height |
ST001274 | AN002115 | Metabolomics-based profiling of the mode of action of Pathogen Box compounds in Trypanosoma brucei (part-I) | Cultured cells | Trypanosoma brucei | Sleeping sickness | Monash University | Peak height |
ST003160 | AN005184 | New class of heterospirocyclic compounds present strong and rapid activity against artemisinin- and multidrug-resistant P. falciparum parasites | Plasmodium cells | Plasmodium falciparum | Malaria | Monash University | Peak height |
ST003179 | AN005221 | Property and Activity Refinement of Dihydroquinazolinone-3-carboxamides as Orally Efficacious Antimalarials that Target PfATP4 | Plasmodium cells | Plasmodium falciparum | Malaria | Monash University | Peak height |
ST001201 | AN001999 | Peroxide antimalarial treatment timecourse on trophozoite-stage P. falciparum parasites | Cultured cells | Human | Malaria | Monash University | Peak intensity |
ST001201 | AN001999 | Peroxide antimalarial treatment timecourse on trophozoite-stage P. falciparum parasites | Cultured cells | Plasmodium falciparum | Malaria | Monash University | Peak intensity |
ST001202 | AN002001 | Peroxide antimalarial treatment timecourse on ring-stage P. falciparum parasites | Cultured cells | Human | Malaria | Monash University | Peak intensity |
ST001202 | AN002001 | Peroxide antimalarial treatment timecourse on ring-stage P. falciparum parasites | Cultured cells | Plasmodium falciparum | Malaria | Monash University | Peak intensity |
ST001205 | AN002006 | Peroxide antimalarial treatment of K13-mutant and -wildtype P. falciparum parasites | Cultured cells | Human | Malaria | Monash University | Peak intensity |
ST001205 | AN002006 | Peroxide antimalarial treatment of K13-mutant and -wildtype P. falciparum parasites | Cultured cells | Plasmodium falciparum | Malaria | Monash University | Peak intensity |
ST001547 | AN002576 | β-Adrenergic regulation of metabolism in macrophages | Macrophages | Human | Monash University | Peak intensity | |
ST001547 | AN002577 | β-Adrenergic regulation of metabolism in macrophages | Macrophages | Human | Monash University | Peak intensity | |
ST001548 | AN002578 | β-Adrenergic regulation of metabolism in macrophages (part-II) | Macrophages | Human | Monash University | Peak intensity | |
ST001548 | AN002579 | β-Adrenergic regulation of metabolism in macrophages (part-II) | Macrophages | Human | Monash University | Peak intensity | |
ST001549 | AN002580 | β-Adrenergic regulation of metabolism in macrophages (part-III) | Macrophages | Human | Monash University | Peak intensity | |
ST001549 | AN002581 | β-Adrenergic regulation of metabolism in macrophages (part-III) | Macrophages | Human | Monash University | Peak intensity | |
ST000452 | AN000708 | The alpha-1A adrenergic receptor agonist A61603 reduces cardiac polyunsaturated fatty acid-Serum raw data | Blood | Mouse | University of North Carolina | Peak values (scaled) | |
ST001745 | AN002838 | Metabolomic profiling of the rat hippocampus across developmental ages and after learning | Brain | Rat | New York University | pmoles/l | |
ST001827 | AN002963 | The pregnancy metabolome from a multi-ethnic pregnancy cohort | Blood | Human | Icahn School of Medicine at Mount Sinai | pmoles/l | |
ST001983 | AN003234 | Metabolomic Fingerprinting of Human High Grade Serous Ovarian Carcinoma Cell Lines | Ovarian cancer cells | Human | Cancer | University of Oklahoma Health Sciences Center | ratio |
ST001835 | AN002977 | Use of Integrated Metabolomics, Transcriptomics, and Signal Protein Profile to Characterize the Effector Function and Associated Metabotype of Polarized Macrophage Phenotypes | Blood | Human | Idaho Veterans Research and Education Foundation | raw area count | |
ST000899 | AN001462 | Alterations in Lipid, Amino Acid, and Energy Metabolism Distinguish Crohn Disease from Ulcerative Colitis and Control Subjects by Serum Metabolomic Profiling | Blood | Human | Inflammatory bowel disease | Vanderbilt University Medical Center | raw area counts |
ST001400 | AN002340 | Identification of distinct metabolic perturbations and associated immunomodulatory events during intra-erythrocytic development stage of pediatric Plasmodium falciparum malaria | Blood | Human | Malaria | New York University Abu Dhabi | raw area counts |
ST001516 | AN002515 | Identification of distinct metabolic perturbations and associated immunomodulatory events during intra-erythrocytic development stage of pediatric Plasmodium falciparum malaria (part-II) | Blood | Human | Malaria | New York University Abu Dhabi | raw area counts |
ST001517 | AN002518 | Identification of distinct metabolic perturbations and associated immunomodulatory events during intra-erythrocytic development stage of pediatric Plasmodium falciparum malaria (part-III) | Blood | Human | Malaria | New York University Abu Dhabi | raw area counts |
ST001749 | AN002848 | REACH Metabolomics Study | Blood | Human | Alzheimers disease | University of Wisconsin - Madison | Raw area counts |
ST002818 | AN004586 | Evaluation of Novel Candidate Filtration Markers from a Global Metabolomics Discovery for Glomerular Filtration Rate Estimation (ALTOLD) | Blood | Human | Tufts Medical Center | raw area counts rescaled to set the median equal to 1 | |
ST002819 | AN004590 | Evaluation of Novel Candidate Filtration Markers from a Global Metabolomics Discovery for Glomerular Filtration Rate Estimation (MDRD) | Blood | Human | Tufts Medical Center | raw area counts rescaled to set the median equal to 1 | |
ST002820 | AN004594 | Evaluation of Novel Candidate Filtration Markers from a Global Metabolomics Discovery for Glomerular Filtration Rate Estimation (AASKG1) | Blood | Human | Tufts Medical Center | raw area counts rescaled to set the median equal to 1 | |
ST002090 | AN003414 | Commensal intestinal microbiota regulates host luminal proteolytic activity and intestinal barrier integrity through β-glucuronidase activity (Part 2) | Feces | Mouse | Irritable bowel syndrome | Mayo Clinic | raw intensity |
ST003131 | AN005135 | Untargeted Metabolomics on mouse caecal contents | Cecum | Mouse | University College Cork | Raw Peak Area | |
ST003132 | AN005139 | Untargeted Metabolomics on Mouse colonic mucosa | Colonic mucosa | Mouse | University College Cork | Raw Peak Area | |
ST001404 | AN002346 | Ontogeny related changes in the pediatric liver metabolome (part-III) | Liver | Human | Moffitt Cancer Center | Relative Abundance | |
ST002836 | AN004633 | Bacterial tryptophan metabolites increased by prebiotic galactooligosaccharide reduce microglial reactivity and are associated with lower anxiety-like behavior (Intestine) | Intestine | Mouse | Anxiety | National Center for Advancing Translational Sciences | Relative Abundance |
ST002837 | AN004637 | Bacterial tryptophan metabolites increased by prebiotic galactooligosaccharide reduce microglial reactivity and are associated with lower anxiety-like behavior (Blood) | Blood | Mouse | Anxiety | National Center for Advancing Translational Sciences | Relative Abundance |
ST002206 | AN003609 | Lipolysis-derived Lipids Determine Autophagy Initiation during Fasting | Worms | C. elegans | Seoul National University | relative area | |
ST001668 | AN002720 | D-Allulose effects on hepatic metabolomics profile in rodents | Liver | Rat | Matsutani Chemical Industry Co., Ltd. | Relative Area | |
ST002584 | AN004256 | Metabolomics analysis of ALDH1L1-expressing HuH7 cell lines. | Cultured cells | Human | Cancer | Tohoku Medical and Pharmaceutical University | Relative Area |
ST002088 | AN003406 | Plasma Metabolomic signatures of COPD in a SPIROMICS cohort: A metabolomic severity score for airflow obstructions and emphysema | Blood | Human | COPD | National Jewish Health | relativeMedian |
ST002089 | AN003410 | Plasma metabolomic signatures of COPD: A metabolomic severity score for airflow obstruction and emphysema. | Blood | Human | COPD | National Jewish Health | relativeMedian |
ST002017 | AN003287 | Multi-omic analysis of the microbiome and metabolome in healthy subjects (blood) | Blood | Human | Vanderbilt University Medical Center | scaled imputed | |
ST002018 | AN003288 | Multi-omic analysis of the microbiome and metabolome in healthy subjects (feces) | Feces | Human | Vanderbilt University Medical Center | scaled imputed | |
ST002019 | AN003289 | TIPs Metabolomics (blood) | Blood | Human | Vanderbilt University Medical Center | scaled imputed | |
ST000930 | AN001524 | Define alterations in the gut metabolome of mice infected with C. difficile | Intestine | Mouse | North Carolina State University | scaled intensity | |
ST001515 | AN002511 | A Metabolomic Signature of Glucagon Action in Healthy Individuals with Overweight/Obesity Humans | Blood | Human | Obesity | Translational Research Institute- AdventHealth Orlando | scaled units |
ST001175 | AN001950 | Multi-omics analysis demonstrates unique mode of action of a potent new antimalarial compound, JPC-3210, against Plasmodium falciparum | Plasmodium cells | Plasmodium falciparum | Malaria | Monash University | Signal Intensity |
ST001304 | AN002172 | Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii | Fibroblast cells | Toxoplasma gondii | Parasitic infection | Monash University | Signal Intensity |
ST001253 | AN002079 | Phenotyping Mouse blood metabolites in day and night in type 2 diabetes | Blood | Mouse | Diabetes | Indiana University School of Medicine | VolNormImp Area counts |