List of Studies ( Metabolite:D-2-Hydroxyglutaric acid)
| Study_id | Analysis_id | Study_title | Source | Species | Disease | Institute | Units(range) |
|---|---|---|---|---|---|---|---|
| ST002497 | AN004101 | Postnatal hyperglycemia alters amino acid profile in retinas | Retina | Mouse | Eye disease | Boston Childrens Hospital | Absolute Intensity |
| ST002830 | AN004623 | L-isoleucine in P10 STZ | Retina | Mouse | Retinopathy of prematurity | Boston Childrens Hospital | abundance/intensity |
| ST003102 | AN005076 | Cellular adaptation to cancer therapy occurs by progressive state transitions along a resistance continuum | Ovarian cancer cells | Human | Cancer | NYU Langone Health | Arbitrary units |
| ST002327 | AN003796 | Effect of PARK7 gene KO on midbrain organoids | Cultured cells | Human | Icahn School of Medicine at Mount Sinai | intensity | |
| ST000904 | AN001471 | Measurement of 2-hydroxyglutarate for reproducibility project | Cultured cells | Human | Cancer | Sanford Burnham Prebys Medical Discovery Insititute | ion count |
| ST001860 | AN003015 | Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters | Cultured cells | Human | University of British Columbia | ion counts | |
| ST002847 | AN004665 | Targeting Pancreatic Cancer Metabolic Dependencies through Glutamine Antagonism. | Cultured cells | Mouse | Cancer | New York University | ion counts |
| ST002535 | AN004170 | Relationships between the gut microbiome and cognitive impairment in residents of long-term aged care. | Feces | Human | Cognitive impairment | South Australian Health and Medical Research Institute | ng/ml |
| ST002174 | AN003562 | Identifying a tryptophan derivative in hydrogen peroxide-treated cell culture medium | Media | Abiotic | NYU Langone Health | N/L | |
| ST002160 | AN003539 | Global metabolomics analysis of neutrophils isolated from tumor | Tumor cells | Mouse | Cancer | The Wistar Institute | Normalized MS Peak Area |
| ST002216 | AN003625 | Non-targeted metabolomics screen comparing metabolite profiles of serum from PDAC-bearing mice that received metronidazole using high-resolution, high-performance LC-MS/MS analysis. | Blood | Mouse | Cancer | The Wistar Institute | Normalized Peak Area |
| ST002217 | AN003626 | Non-targeted metabolomics screen comparing metabolite profiles of serum from PDAC-bearing mice that received 1% choline supplementation or control diet using high-resolution, high-performance LC-MS/MS analysis. | Blood | Mouse | Cancer | The Wistar Institute | Normalized Peak Area |
| ST001719 | AN002802 | Metabolomics Analysis of Philadelphia Cohort - Update (part-I) | Blood | Human | HIV | The Wistar Institute | Peak area |
| ST001720 | AN002803 | Metabolomics Analysis of ACTG Cohort -Update (part-II) | Blood | Human | HIV | The Wistar Institute | Peak area |
| ST003112 | AN005111 | Glucose Hypometabolism Prompts RAN Translation and Exacerbates C9orf72-related ALS/FTD Phenotypes | Brain | Mouse | Neurodegenerative Disorder | Thomas Jefferson University | peak intensity |
| ST003113 | AN005098 | Inhibition of Asparagine Synthetase Effectively Retards Polycystic Kidney Disease Progression, investigated with targeted tracing metabolomics analysis in MEF cells using 15N2-glutamine. | Cultured cells | Mouse | Kidney disease | San Raffaele University | peak intensity |
| ST003113 | AN005099 | Inhibition of Asparagine Synthetase Effectively Retards Polycystic Kidney Disease Progression, investigated with targeted tracing metabolomics analysis in MEF cells using 15N2-glutamine. | Cultured cells | Mouse | Kidney disease | San Raffaele University | peak intensity |
| ST003118 | AN005112 | Glucose Hypometabolism Prompts RAN Translation and Exacerbates C9orf72-related ALS/FTD Phenotypes - Study 2 | Brain | Mouse | Neurodegenerative Disorder | Thomas Jefferson University | peak intensity |
| ST001114 | AN001810 | Metabolomics profile of umbilical cord blood is associated with maternal pre-pregnant obesity in a perspective multi-ethnic cohort displaying health disparities | Blood | Human | Obesity | University of Hawaii Cancer center | Peak intensity |
| ST002541 | AN004187 | Methionine restriction constrains lipoylation and activates mitochondria for nitrogenic synthesis of amino acids (Part 1) | Yeast cells | Yeast | Life Sciences Institute, ZheJiang University | Peak intensity | |
| ST002542 | AN004189 | Methionine restriction constrains lipoylation and activates mitochondria for nitrogenic synthesis of amino acids (Part 2) | Yeast cells | Yeast | Life Sciences Institute, ZheJiang University | Peak intensity | |
| ST002872 | AN004708 | Comparative multi-omics analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency | Heart | Mouse | Cardiomyopathy | Weill Cornell Medicine | Peak intensity |
| ST002872 | AN004708 | Comparative multi-omics analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency | Heart | Mouse | Friedreichs Ataxia | Weill Cornell Medicine | Peak intensity |
| ST002068 | AN003370 | Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy | Heart | Mouse | Heart disease | Weill Cornell Medicine | Peak Intensity |
| ST002068 | AN003371 | Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy | Heart | Mouse | Heart disease | Weill Cornell Medicine | Peak Intensity |
| ST003126 | AN005125 | Effect of high fat diet on heart metabolome of CHCHD10 mutant mice | Heart | Mouse | Cardiomyopathy | Weill Cornell Medicine | Peak Intensity |
| ST003128 | AN005128 | Effect of high fat diet on serum lipidome and metabolome in CHCHD10 Mutant Mice | Blood | Mouse | Cardiomyopathy | Weill Cornell Medicine | Peak Intensity |
| ST002094 | AN003420 | Commensal intestinal microbiota regulates host luminal proteolytic activity and intestinal barrier integrity through β-glucuronidase activity (Part 1) | Feces | Human | Irritable bowel syndrome | Mayo Clinic | raw intensity |
| ST002094 | AN003421 | Commensal intestinal microbiota regulates host luminal proteolytic activity and intestinal barrier integrity through β-glucuronidase activity (Part 1) | Feces | Human | Irritable bowel syndrome | Mayo Clinic | raw intensity |
| ST000820 | AN001303 | 2 hydroxyglutarate prodution in neurospheres from IDH1 mouse glioma model #2 | Glioma cells | Mouse | Cancer | University of Michigan | uM |
| ST001669 | AN002724 | Serum metabolome of Guangzhou Nutrition and Health Study (GNHS) | Blood | Human | Westlake University | uM | |
| ST000312 | AN000498 | IDH1R132H activity in glioma cell lines and tumnor tissue (2HG) | Cells | Mouse | Cancer | University of Michigan | uM/500ul extraction solvent |
| ST000821 | AN001304 | Metabolomic profiling of IDH1 mutation | Astrocyte cells | Human | Cancer | University of Michigan | uM/ng protein |
| ST000822 | AN001305 | Metabolomic profiling of IDH1 mutation (part II) | Astrocyte cells | Human | Cancer | University of Michigan | uM/ng protein |
| ST000378 | AN000612 | 2 hydroxiglutarate with with IDH1-R132H inhibitor in neurospheres | Neurospheres | Mouse | University of Michigan | umol/g | |
| ST002337 | AN003819 | Guangzhou Nutrition and Health Study (GNHS) | Feces | Human | Westlake University | umol/L |
