| Analysis | Metabolite Name | Measured Value | Units | Sample source | Isotopic Tracer | Drug Treatment |
|---|---|---|---|---|---|---|
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 30007.54 | AU | BT-474 | NA | NA |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 34556.86 | AU | BT-474 | NA | NA |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 70663.25 | AU | BT-474 | NA | NA |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 111405.1 | AU | BT-474 | NA | NA |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 86600000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 89900000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 91600000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 96300000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 98200000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 101000000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 118000000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 119000000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 130000000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 131000000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 135000000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 253000000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 262000000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 271000000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 319000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 337000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C12 PARENT | 344000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 4790.404 | AU | BT-474 | NA | NA |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 5720.707 | AU | BT-474 | NA | NA |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 12700000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 13000000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 13500000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 21200000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 23000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 23200000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 29300000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 32500000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 33100000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 35400000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 36600000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 37000000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 77600000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 79200000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 80400000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 80900000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 84000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | 87900000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-1 | AU | BT-474 | NA | NA | |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 23100000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 24500000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 24700000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 33800000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 35900000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 37600000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 42000000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 43200000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 48200000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 49400000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 49700000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 98800000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 106000000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 110000000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 115000000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 120000000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | 121000000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-2 | AU | BT-474 | NA | NA | |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 3160.883 | AU | BT-474 | NA | NA |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 27000000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 27400000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 27900000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 30000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 31100000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 31300000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 56800000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 58200000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 59900000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 60000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 60800000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 61900000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 75800000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 80700000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 83900000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 91200000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 96100000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | 97300000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-3 | AU | BT-474 | NA | NA | |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 6273534 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 6388208 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 6420162 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 7016868 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 7346708 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 7563186 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 7779182 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 7845354 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 8450765 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 30400000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 31200000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 32300000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 32500000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 80400000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 82900000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 87700000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 99900000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | 105000000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-4 | AU | BT-474 | NA | NA | |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 3666.836 | AU | BT-474 | NA | NA |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 15116.99 | AU | BT-474 | NA | NA |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 21700000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 24400000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 25500000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 25800000 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 62800000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 64200000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 68000000 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 85800000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 91000000 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 97700000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 102000000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 103000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 104000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 105000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 107000000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 121000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | 130000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamate C13-label-5 | AU | BT-474 | NA | NA | |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 26789.85 | AU | BT-474 | NA | NA |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 1349473 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 1713630 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 1727489 | AU | BT-474 | [13C6] D-glucose | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 2076718 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 2097363 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 2247611 | AU | BT-474 | [13C6] D-glucose | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 2375128 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 2425875 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 2763316 | AU | BT-474 | [13C6] D-glucose | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 401000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 403000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 411000000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 415000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM Fasnall |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 439000000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 483000000 | AU | BT-474 | [13C5] L-glutamine | Vehicle |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 552000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 584000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | 586000000 | AU | BT-474 | [13C5] L-glutamine | 1 uM GSK2194069 |
| HILIC NEGATIVE ION MODE | L-Glutamine C13-label-5 | AU | BT-474 | NA | NA |
- UCSD Metabolomics Workbench, a resource sponsored by the Common Fund of the National Institutes of Health
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