Data for ST001025
Metabolite structure | All data | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 | F19 | F20 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2-Hydroxyglutarate M0 | 94.28 | 86.21 | 90.29 | 82.35 | 94.39 | 89.26 | 64.24 | 80.80 | 69.12 | 97.63 | 93.04 | 91.92 | 90.95 | 92.47 | 90.42 | 87.45 | 92.14 | 87.95 | 92.78 | 93.52 | |
2-Hydroxyglutarate M+1 | 0.90 | 1.14 | 3.09 | 1.25 | - | 0.82 | 3.75 | 1.11 | 3.21 | 1.56 | 2.71 | 3.48 | 1.70 | 3.66 | 3.79 | 1.82 | 3.08 | 1.75 | 2.76 | 2.59 | |
2-Hydroxyglutarate M+2 | 2.33 | 0.36 | 4.25 | 0.78 | - | 3.71 | 2.25 | 3.54 | 2.07 | 0.61 | 1.20 | 0.17 | 0.71 | 0.77 | 0.26 | 0.97 | - | 0.55 | - | 0.42 | |
2-Hydroxyglutarate M+3 | 0.54 | 3.17 | 1.48 | 4.00 | 0.33 | 0.06 | 7.34 | 0.17 | 6.38 | 0.01 | 1.69 | 1.02 | 1.13 | 0.76 | 1.37 | 1.39 | 1.11 | 1.37 | 0.97 | 1.05 | |
2-Hydroxyglutarate M+4 | 0.23 | 0.07 | 0.28 | 0.09 | 0.02 | 0.13 | 0.71 | 0.18 | 0.52 | - | 0.43 | 0.02 | 0.68 | 0.17 | - | 1.24 | 0.35 | 1.15 | 0.35 | 0.29 | |
2-Hydroxyglutarate M+5 | 1.52 | 8.27 | 1.18 | 9.67 | 0.20 | 0.01 | 18.59 | 0.02 | 16.66 | 0.63 | 2.62 | 2.99 | 5.65 | 2.19 | 4.25 | 7.58 | 3.30 | 7.37 | 3.12 | 2.86 | |
2-Hydroxyglutarate M+6 | 0.09 | - | 0.04 | - | 0.04 | 0.13 | - | 0.35 | - | - | - | - | - | 0.04 | 0.02 | - | - | - | - | - | |
2-Hydroxyglutarate M+7 | 0.16 | 1.53 | 1.24 | 2.30 | 5.03 | 6.15 | 3.13 | 13.82 | 2.04 | 0.48 | 0.47 | 0.55 | 0.31 | 0.77 | 0.24 | 0.11 | 0.05 | 0.08 | 0.06 | 0.14 | |
Alanine M0 | 97.23 | 99.41 | 97.48 | 99.22 | 99.57 | 90.16 | 98.07 | 92.42 | 98.35 | 99.36 | 99.65 | 99.27 | 99.49 | 99.42 | 99.47 | 98.65 | 99.83 | 98.69 | 99.71 | 99.85 | |
Alanine M+1 | 0.40 | 0.28 | - | 0.40 | 0.30 | 1.64 | 1.14 | 1.07 | 0.90 | 0.51 | 0.04 | 0.60 | - | 0.36 | 0.36 | - | 0.09 | - | 0.21 | 0.12 | |
Alanine M+2 | 2.50 | 0.30 | 2.51 | 0.37 | 0.12 | 8.19 | 0.78 | 6.50 | 0.74 | 0.18 | 0.75 | 0.19 | 1.50 | 0.21 | 0.16 | 2.40 | 0.14 | 2.35 | 0.17 | 0.05 | |
Alanine M+3 | - | - | - | - | - | - | - | - | - | 0.01 | 0.01 | - | 0.01 | - | - | 0.02 | 0.02 | 0.01 | 0.03 | 0.01 | |
Aspartate M0 | 94.55 | 76.19 | 92.32 | 74.48 | 97.97 | 94.21 | 64.11 | 93.35 | 70.39 | 99.19 | 98.58 | 96.32 | 98.24 | 94.64 | 99.41 | 98.06 | 83.54 | 97.74 | 84.89 | 94.67 | |
Aspartate M+1 | 2.26 | 3.84 | 2.83 | 4.66 | 1.66 | 2.17 | 5.39 | 2.37 | 4.48 | 0.75 | 1.12 | 0.59 | 0.43 | 1.15 | 0.32 | 1.69 | 2.09 | 3.23 | 0.24 | 2.56 | |
Aspartate M+2 | 2.84 | 5.21 | 4.30 | 6.08 | 0.36 | 2.85 | 8.56 | 3.38 | 6.97 | 0.07 | 0.41 | 1.28 | 1.62 | 1.55 | 0.15 | - | 1.74 | - | 2.65 | 0.06 | |
Aspartate M+3 | 0.32 | 2.00 | 0.49 | 1.96 | - | 0.76 | 3.19 | 0.89 | 2.58 | - | 0.81 | 0.84 | 0.95 | 0.77 | 0.18 | 0.63 | 9.58 | 0.69 | 10.74 | 3.15 | |
Aspartate M+4 | 0.04 | 12.76 | 0.04 | 12.82 | - | - | 18.74 | 0.01 | 15.58 | 0.02 | 0.28 | 4.72 | 0.18 | 7.80 | - | 0.54 | 10.87 | 0.15 | 5.30 | 1.56 | |
Aspartate M+5 | - | - | 0.02 | - | 0.01 | 0.01 | - | - | - | - | 0.02 | 0.05 | 0.08 | 0.02 | 0.04 | 0.24 | 2.26 | 0.13 | 0.81 | 0.57 | |
Citrate M0 | 89.02 | 77.24 | 84.87 | 76.04 | 98.39 | 88.44 | 65.97 | 86.86 | 70.62 | 99.87 | 98.69 | 98.57 | 97.32 | 97.77 | 98.99 | 99.11 | 96.28 | 97.89 | 94.87 | 99.41 | |
Citrate M+1 | 2.29 | 3.23 | 3.06 | 4.09 | 0.40 | 2.46 | 4.68 | 2.84 | 3.99 | - | 0.79 | 0.62 | 1.24 | 0.72 | 0.86 | 0.16 | 0.60 | 0.62 | 1.41 | 0.40 | |
Citrate M+2 | 8.18 | 5.26 | 11.00 | 6.09 | 0.02 | 8.37 | 7.96 | 9.31 | 6.82 | 0.20 | 0.66 | 0.06 | 1.74 | 1.08 | 0.53 | 1.68 | 1.09 | 1.95 | 1.26 | 0.26 | |
Citrate M+3 | 0.31 | 1.99 | 0.64 | 2.04 | 0.13 | 0.52 | 3.89 | 0.68 | 3.39 | 0.05 | 0.24 | 0.13 | - | 0.81 | - | 0.15 | 0.84 | 0.48 | 1.19 | 0.16 | |
Citrate M+4 | 0.17 | 11.79 | 0.35 | 11.21 | - | 0.16 | 15.68 | 0.24 | 13.20 | 0.03 | 0.25 | 1.02 | 0.33 | 2.41 | 0.41 | 0.06 | 2.50 | 0.13 | 2.72 | 0.20 | |
Citrate M+5 | - | - | 0.07 | 0.26 | - | 0.05 | 1.66 | 0.05 | 1.89 | - | 0.14 | 0.12 | 0.20 | 0.15 | 0.03 | 0.05 | 0.28 | 0.12 | 0.61 | 0.06 | |
Citrate M+6 | 0.03 | 0.12 | - | 0.13 | 0.03 | 0.01 | 0.14 | 0.01 | 0.13 | - | - | 0.08 | 0.10 | 0.09 | 0.10 | 0.04 | 0.07 | 0.02 | 0.04 | 0.03 | |
Citrate M+7 | - | 0.37 | 0.01 | 0.16 | 1.05 | - | 0.04 | 0.01 | - | 0.01 | 0.14 | 0.06 | 0.03 | 0.12 | 0.02 | 0.01 | 0.04 | 0.05 | 0.04 | 0.05 | |
Fumarate M0 | 96.13 | 79.28 | 95.71 | 77.42 | 99.77 | 95.53 | 75.16 | 95.72 | 76.02 | 97.71 | 98.27 | 95.95 | 99.35 | 95.17 | 88.81 | 98.08 | 91.73 | 98.50 | 93.12 | 89.37 | |
Fumarate M+1 | 1.98 | 2.33 | 1.85 | 3.09 | - | 1.32 | 3.93 | 1.24 | 3.36 | 1.01 | 1.23 | - | - | - | 1.42 | - | - | - | - | 0.38 | |
Fumarate M+2 | 1.70 | 4.45 | 2.00 | 5.19 | 0.17 | 2.37 | 5.76 | 2.39 | 5.51 | 0.57 | 1.25 | 0.52 | 0.74 | 1.51 | 2.13 | 1.62 | 1.93 | 1.27 | 1.48 | 2.95 | |
Fumarate M+3 | 0.18 | 1.77 | 0.39 | 1.86 | 0.09 | 0.78 | 2.14 | 0.62 | 2.12 | 0.04 | 0.39 | 0.69 | 0.27 | 0.49 | 1.24 | 0.17 | 0.98 | - | 1.00 | 1.22 | |
Fumarate M+4 | 0.04 | 12.17 | 0.07 | 12.44 | 0.08 | 0.02 | 13.01 | 0.03 | 13.00 | 0.68 | 0.26 | 3.13 | 0.54 | 3.33 | 6.63 | 0.43 | 5.36 | 0.24 | 4.40 | 6.33 | |
Fumarate M+5 | - | - | - | - | - | - | - | - | - | - | - | - | 0.04 | - | - | - | - | - | - | - | |
Glutamate M0 | 91.70 | 73.86 | 90.79 | 72.66 | 99.46 | 93.32 | 58.99 | 92.40 | 64.85 | 98.71 | 98.22 | 96.08 | 97.97 | 94.04 | 99.82 | 97.80 | 87.76 | 97.69 | 89.01 | 99.47 | |
Glutamate M+1 | 3.85 | 2.19 | 3.27 | 2.77 | 0.45 | 2.35 | 3.89 | 2.62 | 3.54 | 1.24 | 0.82 | 0.85 | 1.07 | 0.80 | - | 0.54 | 1.91 | 0.75 | 1.16 | - | |
Glutamate M+2 | 4.41 | 1.53 | 5.65 | 1.91 | 0.07 | 4.18 | 2.61 | 4.79 | 2.15 | - | 0.68 | 0.34 | 1.27 | 1.02 | 0.03 | 1.20 | 1.18 | 1.04 | 1.53 | 0.20 | |
Glutamate M+3 | - | 4.97 | 0.16 | 5.66 | 0.03 | 0.10 | 9.57 | 0.13 | 8.01 | 0.05 | 0.38 | 1.14 | 0.10 | 1.17 | 0.14 | 0.60 | 2.38 | 0.57 | 2.15 | 0.32 | |
Glutamate M+4 | 0.03 | 0.51 | 0.10 | 0.49 | - | 0.03 | 1.01 | 0.06 | 0.79 | 0.04 | 0.03 | 0.14 | 0.04 | 0.23 | 0.07 | 0.11 | 0.73 | 0.05 | 0.41 | - | |
Glutamate M+5 | 0.01 | 16.93 | 0.01 | 16.52 | 0.01 | - | 23.93 | - | 20.66 | - | 0.02 | 3.32 | 0.01 | 5.65 | 0.07 | - | 10.49 | - | 11.13 | 0.29 | |
Glutamate M+6 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
Glutamine M0 | 98.77 | 66.05 | 99.61 | 66.04 | 97.83 | 94.87 | 54.42 | 96.85 | 61.74 | 98.93 | 99.08 | 74.67 | 99.40 | 75.71 | 98.83 | 99.70 | 69.00 | 99.71 | 73.89 | 99.67 | |
Glutamine M+1 | 0.68 | 0.95 | - | 0.80 | 1.92 | 2.82 | 1.20 | 1.40 | 1.27 | 0.89 | 1.24 | 0.92 | 0.60 | 0.47 | 0.17 | - | - | - | 1.13 | - | |
Glutamine M+2 | 0.53 | 0.18 | 0.33 | 0.28 | 0.20 | 2.29 | 0.59 | 1.73 | 0.68 | 0.17 | 0.90 | 0.92 | 0.49 | 1.04 | 0.83 | 0.32 | 0.33 | 0.47 | 0.36 | 0.38 | |
Glutamine M+3 | - | 0.14 | 0.09 | 0.20 | - | - | 1.91 | - | 2.13 | - | 0.23 | 0.03 | 0.34 | 0.18 | 1.03 | 0.14 | 0.36 | 0.05 | 0.44 | 0.14 | |
Glutamine M+4 | 0.02 | 1.30 | - | 1.29 | 0.01 | - | 1.85 | 0.01 | 1.41 | 0.02 | 0.05 | 1.17 | 0.01 | 1.27 | 0.04 | 0.01 | 2.15 | 0.04 | 1.70 | 0.01 | |
Glutamine M+5 | 0.02 | 31.36 | 0.01 | 31.39 | 0.03 | 0.02 | 39.97 | 0.01 | 32.74 | 0.01 | 0.03 | 22.72 | 0.04 | 22.23 | 0.04 | 0.04 | 29.01 | 0.03 | 23.92 | 0.12 | |
Glutamine M+6 | - | - | - | - | - | - | - | - | - | - | 0.03 | - | - | 0.06 | 0.07 | 0.01 | 0.02 | 0.05 | 0.04 | 0.02 | |
Glutamine M+7 | - | 0.04 | - | - | - | - | 0.06 | - | 0.03 | - | 0.01 | 0.10 | 0.01 | - | 0.01 | - | 0.10 | 0.01 | 0.17 | - | |
Ketoglutarate M0 | 93.85 | 75.03 | 90.44 | 73.68 | 97.04 | 92.65 | 61.89 | 90.90 | 66.62 | 98.49 | 96.10 | 95.09 | 94.81 | 93.21 | 98.64 | 99.17 | 89.21 | 98.92 | 88.96 | 97.33 | |
Ketoglutarate M+1 | 1.48 | 3.06 | 2.29 | 3.11 | 1.00 | 1.84 | 4.27 | 2.14 | 3.94 | 0.64 | 2.54 | 1.61 | 3.41 | 1.38 | 1.12 | 0.22 | 1.32 | 0.34 | 1.17 | 1.04 | |
Ketoglutarate M+2 | 3.59 | 1.27 | 5.44 | 1.71 | 0.03 | 4.05 | 2.66 | 4.60 | 2.22 | 0.03 | 0.82 | 0.52 | 1.73 | 0.72 | 0.21 | 0.63 | 0.52 | 0.85 | 0.52 | 0.04 | |
Ketoglutarate M+3 | 0.60 | 4.77 | 1.02 | 5.47 | 0.20 | 0.14 | 9.02 | 0.17 | 7.61 | 0.07 | 0.26 | 0.72 | 0.28 | 1.30 | 0.29 | 0.12 | 4.42 | 0.14 | 2.61 | 1.70 | |
Ketoglutarate M+4 | 0.11 | 0.32 | 0.30 | 0.37 | 0.08 | 0.20 | 0.83 | 0.33 | 0.67 | 0.07 | 0.41 | 0.07 | 0.59 | 0.17 | 0.10 | 0.08 | 0.32 | 0.08 | 0.47 | 0.04 | |
Ketoglutarate M+5 | 0.07 | 14.46 | 0.18 | 15.18 | - | 0.07 | 21.17 | 0.10 | 18.77 | 0.09 | 0.41 | 6.34 | 0.04 | 5.54 | 0.03 | 0.02 | 5.65 | 0.02 | 7.07 | 0.09 | |
Ketoglutarate M+6 | - | - | - | - | 0.01 | 0.92 | - | 1.36 | - | 0.21 | 0.37 | 0.01 | 0.07 | 0.02 | 0.02 | 0.02 | 0.13 | 0.02 | 0.15 | 0.09 | |
Lactate M0 | 98.90 | 99.50 | 98.75 | 99.42 | 99.88 | 82.27 | 99.20 | 83.29 | 99.22 | 99.93 | 99.01 | 97.13 | 99.57 | 97.66 | 97.44 | 95.90 | 99.14 | 95.81 | 99.25 | 99.19 | |
Lactate M+1 | 2.35 | 0.45 | 2.40 | 0.23 | 0.26 | 0.80 | 0.39 | 0.79 | 0.61 | - | 2.20 | 2.34 | 0.60 | 1.87 | 2.10 | 1.14 | 0.57 | 1.00 | 0.81 | 0.74 | |
Lactate M+2 | 0.59 | 0.06 | 0.69 | 0.03 | - | 1.50 | 0.20 | 1.61 | 0.34 | - | 0.38 | 0.51 | 0.26 | 0.43 | 0.45 | 0.55 | 0.21 | 0.56 | 0.28 | 0.21 | |
Lactate M+3 | 0.17 | 0.30 | 0.22 | 0.30 | 0.02 | 15.43 | 0.41 | 14.31 | 0.46 | 0.06 | 0.12 | 0.04 | 0.26 | 0.09 | - | 7.20 | 0.29 | 7.87 | 0.21 | - | |
Lactate M+4 | - | 0.01 | - | 0.04 | 0.03 | - | - | - | - | 0.01 | 0.02 | - | 0.01 | - | - | - | 0.01 | - | 0.01 | 0.01 | |
Malate M0 | 95.03 | 76.35 | 93.11 | 75.08 | 99.46 | 94.40 | 62.32 | 93.52 | 68.22 | 98.94 | 99.79 | 98.24 | 99.56 | 96.40 | 99.42 | 99.63 | 97.17 | 99.64 | 95.91 | 98.77 | |
Malate M+1 | 1.69 | 3.05 | 1.87 | 3.77 | 0.41 | 1.75 | 5.87 | 2.01 | 4.81 | 0.65 | 0.18 | 0.20 | 0.11 | 0.81 | - | - | 0.48 | - | 0.55 | 0.64 | |
Malate M+2 | 2.73 | 5.06 | 4.28 | 5.81 | 0.09 | 2.89 | 8.90 | 3.25 | 7.49 | 0.17 | 0.09 | 0.42 | 0.39 | 1.32 | - | 0.14 | 1.11 | 0.40 | 1.89 | - | |
Malate M+3 | 0.44 | 2.05 | 0.65 | 1.99 | - | 0.89 | 3.43 | 1.11 | 2.82 | - | 0.07 | 0.43 | 0.15 | 0.61 | 0.28 | 0.10 | 0.35 | 0.08 | 0.55 | 0.10 | |
Malate M+4 | - | 13.50 | 0.02 | 13.34 | - | - | 19.49 | - | 16.67 | - | 0.07 | 1.18 | 0.13 | 2.31 | 0.12 | 0.14 | 1.59 | 0.07 | 2.26 | 0.22 | |
Malate M+5 | 0.11 | - | 0.06 | - | 0.08 | 0.07 | - | 0.12 | - | 0.24 | 0.02 | 0.12 | 0.04 | 0.22 | 0.30 | 0.12 | 0.15 | 0.07 | 0.36 | 0.27 | |
Succinate M0 | 95.63 | 74.88 | 93.94 | 72.66 | 97.58 | 92.88 | 62.63 | 91.03 | 67.46 | 97.19 | 97.99 | 86.41 | 97.21 | 84.91 | 84.65 | 98.08 | 92.21 | 98.18 | 90.32 | 95.22 | |
Succinate M+1 | 2.06 | 4.48 | 2.07 | 6.39 | 2.22 | 2.99 | 6.23 | 4.72 | 5.89 | 2.18 | 0.80 | 11.26 | 1.55 | 11.24 | 11.12 | 1.32 | 3.57 | 1.01 | 4.23 | 3.19 | |
Succinate M+2 | 2.15 | 5.09 | 3.76 | 5.76 | 0.12 | 4.10 | 8.93 | 4.08 | 7.29 | 0.24 | 0.71 | 1.14 | 0.61 | 1.45 | 1.64 | 0.28 | 1.00 | 0.52 | 1.36 | 0.43 | |
Succinate M+3 | 0.02 | 0.79 | 0.02 | 0.80 | - | 0.02 | 0.91 | 0.13 | 0.91 | 0.04 | 0.15 | 0.17 | 0.36 | 0.27 | 0.33 | 0.09 | 0.22 | 0.07 | 0.29 | 0.14 | |
Succinate M+4 | 0.15 | 14.77 | 0.21 | 14.38 | 0.08 | - | 21.31 | 0.02 | 18.44 | 0.37 | 0.61 | 1.33 | 1.17 | 2.45 | 2.26 | 0.25 | 3.00 | 0.22 | 3.80 | 1.04 | |
Succinate M+5 | - | - | - | - | - | 0.02 | - | 0.04 | - | - | - | 0.06 | - | 0.03 | - | 0.01 | - | 0.01 | - | - |
Factors:
F1 | Sample type:Cells | Grouping:IV 12h GLC |
F2 | Sample type:Cells | Grouping:IV 12h GLN |
F3 | Sample type:Cells | Grouping:IV 24h GLC |
F4 | Sample type:Cells | Grouping:IV 24h GLN |
F5 | Sample type:Cells | Grouping:IV Basal |
F6 | Sample type:Cells | Grouping:XVII 12h GLC |
F7 | Sample type:Cells | Grouping:XVII 12h GLN |
F8 | Sample type:Cells | Grouping:XVII 24h GLC |
F9 | Sample type:Cells | Grouping:XVII 24h GLN |
F10 | Sample type:Cells | Grouping:XVII Basal |
F11 | Sample type:Media | Grouping:IV 12h GLC |
F12 | Sample type:Media | Grouping:IV 12h GLN |
F13 | Sample type:Media | Grouping:IV 24h GLC |
F14 | Sample type:Media | Grouping:IV 24h GLN |
F15 | Sample type:Media | Grouping:IV Basal |
F16 | Sample type:Media | Grouping:XVII 12h GLC |
F17 | Sample type:Media | Grouping:XVII 12h GLN |
F18 | Sample type:Media | Grouping:XVII 24h GLC |
F19 | Sample type:Media | Grouping:XVII 24h GLN |
F20 | Sample type:Media | Grouping:XVII Basal |