Data for ST002127   

(Analysis AN003480): Average values per metabolite and experimental factor (Units:Peak Area)

Metabolite structureAll dataF1F2F3F4F5F6F7F8
[13C, 15N]Alanine, 2TBDMS
319333.33 3193333.33 875333.33 1456666.67 314333.33 3143333.33 723666.67 1286666.67
[13C, 15N]Aspartic acid, 3TBDMS
80100.00 801000.00 339666.67 514333.33 80200.00 802000.00 304000.00 484000.00
[13C, 15N]Glutamic acid, 3TBDMS
61933.33 619333.33 228666.67 395666.67 60966.67 609666.67 173333.33 292333.33
[13C, 15N]Glycine, 2TBDMS
55100.00 5743333.33 2706666.67 4270000.00 58533.33 5946666.67 3146666.67 4566666.67
[13C, 15N]Histidine, 3TBDMS
59666.67 596666.67 169333.33 327000.00 52833.33 528333.33 125333.33 259000.00
[13C, 15N]Isoleucine, 2TBDMS
305000.00 3050000.00 1310000.00 2180000.00 345666.67 3456666.67 1135000.00 2233333.33
[13C, 15N]Leucine, 2TBDMS
346666.67 3466666.67 1034666.67 2166666.67 325333.33 3253333.33 777666.67 1646666.67
[13C, 15N]Lysine, 3TBDMS
140000.00 1400000.00 576666.67 798333.33 147333.33 1473333.33 457000.00 794333.33
[13C, 15N]Methionine, 2TBDMS
195000.00 1950000.00 654666.67 1102333.33 197666.67 1976666.67 561000.00 1106666.67
[13C, 15N]Phenylalanine, 2TBDMS
276333.33 2763333.33 1250000.00 1456666.67 248000.00 2480000.00 951666.67 1320000.00
[13C, 15N]Proline, 2TBDMS
175333.33 1753333.33 467000.00 850666.67 165666.67 1656666.67 306333.33 727333.33
[13C, 15N]Serine, 3TBDMS
309000.00 3090000.00 900333.33 2056666.67 338000.00 3380000.00 775666.67 1823333.33
[13C, 15N]Threonine, 3TBDMS
80966.67 809666.67 325666.67 477000.00 71200.00 712000.00 254000.00 360000.00
[13C, 15N]Tyrosine, 3TBDMS
765333.33 7653333.33 2520000.00 3900000.00 722666.67 7226666.67 1963333.33 3470000.00
[13C, 15N]Valine, 2TBDMS
786666.67 7866666.67 2920000.00 4663333.33 792666.67 7926666.67 2226666.67 4110000.00
[13C]Alpha_Ketoglutarate
- 2013333.33 37533.33 28233.33 - 21900.00 51100.00 33500.00
[13C]Citrate
- 42400.00 83100.00 69766.67 - 50366.67 97733.33 82933.33
[13C]Fumatate
- 163666.67 333333.33 256000.00 - 145000.00 361666.67 284666.67
[13C]Malate
- 93200.00 149666.67 128333.33 - 121333.33 175333.33 149000.00
[13C]Succinate
- 125333.33 226333.33 179000.00 - 114000.00 253333.33 202333.33

Factors:

F1Source_Name[gating]:Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) | Treatment:Ctrl, [13C, 15N] AAs were incorporated for 1 h | Batch:1e | Note:[13C, 15N]AAs were used for AA uptake (FigS6.J)
F2Source_Name[gating]:Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) | Treatment:Ctrl, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 0 h | Batch:1e | Note:[13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
F3Source_Name[gating]:Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) | Treatment:Ctrl, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 12 h | Batch:1e | Note:[13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
F4Source_Name[gating]:Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) | Treatment:Ctrl, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 6 h | Batch:1e | Note:[13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
F5Source_Name[gating]:Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) | Treatment:NR 1 week, [13C, 15N] AAs were incorporated for 1 h | Batch:1e | Note:[13C, 15N]AAs were used for AA uptake (FigS6.J)
F6Source_Name[gating]:Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) | Treatment:NR 1 week, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 0 h | Batch:1e | Note:[13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
F7Source_Name[gating]:Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) | Treatment:NR 1 week, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 12 h | Batch:1e | Note:[13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
F8Source_Name[gating]:Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) | Treatment:NR 1 week, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 6 h | Batch:1e | Note:[13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
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