Data for ST002205   

(Analysis AN003608): Average values per metabolite and experimental factor (Units:peak area)

Metabolite structureAll dataF1F2F3F4
1-methylnicotinamide
3394459292.33 2538360261.00 1451432945.33 544007716.63
2/3-phosphoglycerate
45072505.04 50558071.41 55771590.75 66745023.36
2-oxoglutarate
166454000.20 168686133.97 476928817.17 316062858.80
3-phosphoserine
3216051.78 6048230.85 11197474.31 24544793.42
4-hydroxyphenyllactate
8171306.94 8160604.84 23144801.80 23094027.69
4-hydroxyphenylpyruvate
6295642.59 6200750.49 7987444.90 7208209.25
4-hydroxyproline
229211348.33 239743267.17 221765179.10 314715884.47
5-formamidoimidazole-4-carboxamide ribotide
61183.99 52300.30 297631.43 202008.86
6-phosphogluconate
2501774.38 3600560.48 5163931.84 4951522.44
acetyl-CoA
3829867.54 4321580.59 6961341.04 4537475.87
aconitate
16988484.03 19172008.92 104052263.94 111466563.29
adenine
16179299.97 22275469.80 35612962.39 52813410.68
adenosine
10951842.41 12353346.24 8536350.88 10844911.36
adenylosuccinate
2427692.45 2728642.55 8195.92 18881.17
ADP
49550680.06 58297541.13 65760030.79 80834069.79
ADP-ribose
1988195.45 2566157.29 2199299.76 1879005.63
AICAR
- - 51026.20 72881.19
alanine
1072651901.00 1106533863.00 1966981077.33 1815910147.33
aminoimidazole ribonucleotide
638944.90 496050.27 - -
AMP
29177651.12 26405942.04 22647632.08 22153652.44
arginine
2479127067.33 2290942025.67 3283714129.67 3310260486.67
argininosuccinate
236097704.87 235756540.43 4061759.28 5331087.37
asparagine
33522365.98 47967830.41 39497894.84 61995034.42
aspartate
339764536.73 495128750.37 1380722305.67 2361278644.67
ATP
156597233.53 255142134.70 353677132.97 497746334.53
beta-alanine
489482580.73 681189850.20 550942993.20 340458612.10
beta-citrylglutamate
375960.03 368023.82 985944.37 597418.42
betaine
7380937312.00 11307969018.33 13184316247.67 6760225551.00
carnitine
2313706902.67 4153836677.00 2205071874.00 1876498910.33
carnitine C14
2474735.87 9541877.08 2287291.66 1973819.11
carnitine C14:1
6064084.99 10875968.44 7884237.04 10438868.36
carnitine C16
6583030.09 14791955.44 3795554.67 3509092.77
carnitine C16:1
2940918.68 10489424.95 1555202.84 2567631.16
carnitine C18
12679465.85 2143813.64 8096286.22 4623717.80
carnitine C2
1465708892.33 2082140367.67 1106647137.67 587604301.47
carnitine C3
41370957.62 51982667.49 517327484.30 233018581.93
carnitine C4
277933493.27 490641245.07 583212660.40 688327605.60
carnitine C5
11388758.47 22754859.63 53448518.55 25512594.10
carnitine C6
7648579.75 14306471.79 4760167.46 6344518.03
carnosine
16854613.27 21260107.82 28630248.83 30347542.20
CDP
4165776.25 6893258.87 11224330.33 14509130.45
choline
1820526620.33 2035295333.33 1369154179.67 1072411176.73
citicoline
11016020.47 7807482.14 10926645.53 2879524.89
citrate
1557321836.00 1651700578.00 3762012430.33 4469430117.67
citrulline
123177568.77 133334161.57 168337871.03 226824689.40
CMP
2208816.77 2097776.16 4891693.86 4314668.03
CMP-acetylneuraminate
6790610.28 4134525.36 14057701.79 8237347.72
creatine
17299646217.00 14703856935.33 24278614659.67 26866068682.33
creatinine
1186353146.00 1364831945.67 1988352325.33 2374076101.00
CTP
7232507.82 14118934.29 25243457.42 38510801.76
cyclic ADP-ribose
20840185.68 21556874.23 24581944.35 18691732.20
cyclic AMP
533194.87 583423.45 534312.67 490023.12
cystathionine
499686.13 1235310.52 2626316.51 22998129.12
cysteate
3199265.50 3094790.27 2668747.42 3245610.33
cysteinylglycine
40777887.05 39517003.28 26411567.81 53283764.03
cytosine
5808334.27 7971912.41 16157058.00 13437846.86
dATP
55903.33 328300.36 643285.03 1867872.20
dCTP
116551.96 462906.88 1550646.23 2458867.75
deoxycarnitine
314769739.93 433461783.30 573513254.20 379356324.40
dihydroorotate
27282952.09 41970437.17 28588155.47 66531843.09
dihydroxyacetone phosphate
49968230.61 60973453.76 71352886.43 63225769.94
dTMP
384652.00 495928.78 987666.31 1492095.86
dTTP
3309482.05 4681355.33 10411906.30 16172934.01
epsilon-(gamma-glutamyl)lysine
2449690.17 2159303.54 2204631.73 2799968.90
flavin adenine dinucleotide
1744577.18 2022739.22 2660121.02 1460031.65
fructose 6-phosphate
22019470.72 22978680.84 27047545.74 18132736.55
fructose bisphosphate
25548279.81 29272597.45 32656295.93 37312609.64
fumarate
1287894724.33 1430333559.00 190756099.47 165655753.27
gamma-glutamylalanine
10205244.66 13877955.04 9944339.69 10990659.92
gamma-glutamylcysteine
27984414.95 22987532.77 13932025.58 45552224.77
gamma-glutamylglutamate
3711301.92 5387417.22 5694477.33 11028113.35
gamma-glutamylglycine
26479009.65 33644843.60 60905703.18 50201960.39
gamma-glutamylproline
64671215.43 65984865.76 74991782.73 117741677.83
GDP
4225215.26 7503968.17 6438679.58 9667890.50
GDP-fucose
2214398.60 2986191.73 2331263.91 2326293.78
GDP-glucose
966364.78 1010894.28 1019243.54 692921.37
gluconate
246738121.70 294542983.73 725718605.20 548833350.37
glucose
152228557.57 201811620.73 309004738.07 353249830.57
glucose 6-phosphate
35754059.15 44389331.65 47289597.26 26466695.26
glucuronate
6899343.60 8521243.09 7888374.27 6148082.15
glutamate
1645491308.33 1605388293.00 6750803905.33 6471869865.00
glutamine
19374591045.33 19585472788.00 19094244709.67 24976894545.33
glutathione reduced
4258499552.00 4559431268.67 2952431371.33 5269934163.00
glyceraldehyde 3-phosphate
90196834.55 77161010.61 103705039.67 22324031.08
glycerol 3-phosphate
112626129.20 167351883.80 104896648.30 126702908.93
glycerylphosphorylcholine
39825493027.00 53594333172.00 63256969099.00 37293621427.67
Glycerylphosphorylethanolamine
152414925.00 193379409.80 294429322.60 82838578.41
glycine
174152696.77 164879119.53 215441067.43 186517840.73
glycylglycine
2861954.07 2608026.93 5435596.02 8241302.32
GMP
1778759.97 2566499.50 2241626.51 3060408.07
GTP
3877182.27 8578447.66 8338070.70 15173889.63
guanidinoacetate
16833848.97 21778823.60 26574750.38 18310153.23
guanosine
1096177.33 904164.93 2281491.66 1893935.84
hippurate
25949931.83 28160975.14 46304548.17 47102981.12
histidine
3325366880.33 3479310703.67 4679792223.67 6121951446.67
homoarginine
20344043.26 18362412.98 28343809.00 28773520.09
homocitrulline
1457528.38 2087832.06 4883662.25 5058083.88
homocysteine
811171.41 681448.19 1940141.02 2036262.45
hypotaurine
35622774.52 45662214.34 33622779.05 24750850.28
hypoxanthine
17609333.20 22434201.96 81859233.22 72607714.83
IMP
719050.52 603011.08 784887.99 1561716.28
inosine
951486.72 1092419.95 1495011.39 2223557.96
inositol
411929582.80 767159273.00 297312074.80 344856750.40
ketoleucine
17315489.90 18597033.47 48962400.14 54643215.45
ketovaline
2839775.64 2703690.63 6123679.60 8704523.68
kynurenine
7950338.00 8530914.30 14921634.03 16860514.51
lactate
1707521249.33 1556752650.33 1762566926.33 1004578553.33
leucine+isoleucine
9204306825.33 10234296632.33 16078617271.67 16518838082.33
lysine
367641816.37 369250489.13 543558666.90 598238066.10
malate
438322919.40 456238071.00 2481838054.33 2122044690.00
malonate
5883958.23 5382021.18 4951860.35 5207107.79
methionine
3424683644.67 3404550617.33 5423875151.67 7849859373.33
methionine sulfoxide
2099950.56 1741326.40 3456933.73 3432507.20
methylthioadenosine
57125435.75 59838282.91 86956439.97 149584253.87
N2-gamma-glutamylglutamine
3951160.79 4669545.25 4136601.20 8380452.92
N6,N6,N6-trimethyllysine
119812976.10 119399206.43 69312116.80 82789478.65
N-acetylarginine
8870772.91 9375474.11 5608982.12 12042276.23
N-acetylasparagine
2220711.95 2992162.53 5320071.66 4664743.10
N-acetylaspartate
13083837.90 10300595.89 662960953.20 22551572.02
N-acetylaspartylglutamate
1558061.83 2002612.42 7128346.40 6555128.99
N-acetylglutamate
10708532.39 12645270.11 60454636.92 49845536.01
N-acetylglutamine
930523.26 1073315.45 7042795.72 5937692.94
N-acetylhexosamine phosphate
3109856.12 4160112.88 4707232.08 4198022.70
N-acetylhistidine
114486367.80 149752730.87 243942737.00 309817338.73
N-acetylmethionine
19737733.52 25368926.10 26858448.66 42672048.14
N-acetylneuranimic acid
16800734.46 13194174.43 19308966.62 23191316.83
N-acetyltaurine
38336866.58 58297311.73 55114392.50 50613145.75
NAD
222569165.73 233465228.27 253699677.33 185419533.83
NADH
995135.23 1278785.91 1255594.03 1856872.63
NADP
3185536.09 3674742.68 4587529.88 4869161.37
NADPH
1765333.40 2876147.55 3873997.19 4429700.52
N-carbamoylaspartate
15770593.80 18616815.93 14231827.26 16917402.24
N,N-dimethylarginine
76308225.84 70209132.06 87517095.37 100746855.24
ophthalmate
5660735.37 10539674.14 92126216.68 22143178.65
ornithine
4256819.74 3215867.13 8561261.71 10891656.30
orotate
12351344.01 19437825.51 35398994.75 33909273.23
orotidine
6211800.94 7934185.54 22618139.64 14604422.24
oxidized glutathione
6833392.50 11149539.43 6683037.51 28624142.91
pantothenate
509061930.30 537097871.73 467407609.13 639115143.70
pentose 1,5-bisphosphate
71071.86 202731.49 337544.48 143784.02
pentose phosphate
20666499.85 23926212.96 27558838.56 26107997.19
phenylalanine
4407542014.33 5072913264.67 8628981964.00 9596080579.33
phosphocholine
48836401667.00 64243784881.33 59123487350.67 81971603987.00
phosphocreatine
188503054.10 243642180.13 509603450.37 567996757.17
phosphoenolpyruvate
12533510.83 23846204.76 18376102.25 72458242.44
proline
5616357217.67 6347386580.33 27326711295.33 27940254631.00
pyridoxine
35471729.70 42845830.43 60674991.22 67731847.36
pyroglutamate
4442205220.00 5055612697.67 6660061743.67 6735467978.00
pyruvate
55358576.08 69649214.22 108908137.49 113887057.80
quinolinate
4460851.47 5509025.39 8403386.61 9373331.76
S-(2-succinyl)cysteine
110800187.43 81456076.38 335483.87 795880.71
S-adenosylhomocysteine
3180796.92 3677828.85 6325456.35 5841171.77
S-adenosylmethionine
249792083.40 270478001.87 309974233.50 352421352.17
SAICAR
2552210.08 3079717.77 41053.56 63362.87
sarcosine
32122555.65 32764126.58 33316124.77 32689840.11
sedoheptulose 7-phosphate
5014550.16 4994963.90 9117706.61 6310561.19
serine
411784659.73 442110179.40 424056608.97 475622859.67
S-lactoylglutathione
468919.05 413911.50 125825.44 748098.92
S-Succinylglutathione
44870354.58 46755255.12 892010.87 1471544.63
succinate
487522490.37 640132025.13 483554729.77 124366410.37
succinyladenosine
15877124.03 16045901.25 147316.77 379409.78
taurine
2747664570.00 3298848854.33 3454113301.33 3254966739.67
thiamine
425311148.93 512403179.40 821014673.10 930275278.87
threonine
3075143423.67 3140177273.67 3823847153.67 4905662532.67
tryptophan
579798211.00 682455276.70 1199164185.33 1300415177.33
tyrosine
2184416476.00 2560721892.33 4183849517.00 4743288492.00
UDP
35564416.89 46461386.78 72448853.28 77237015.92
UDP-GlcNac
217220747.40 246875500.13 246775835.77 275636091.73
UDP-glucose
105488593.97 108527673.47 166786691.17 161487353.00
UMP
7631125.07 7951831.97 8692842.37 7877062.22
uric acid
29516562.90 36950032.42 35075815.31 80717067.39
uridine
1083646.09 1524600.03 3774877.91 3059187.53
UTP
42499398.48 82990687.42 151160468.63 203642317.20
valine
3294083235.00 3659393387.00 5594280434.33 5992593696.67
xanthine
43912896.45 52929367.02 79292718.39 75490738.46
xanthosine
697709.89 841382.94 1403372.32 1438101.09

Factors:

F1Genotype:Fh1-/- CL19 | Treatment:Cas9
F2Genotype:Fh1-/- CL19 | Treatment:sg1Hira
F3Genotype:Fh1 fl/fl | Treatment:Cas9
F4Genotype:Fh1 fl/fl | Treatment:sg1Hira
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