Data for ST002218   

(Analysis AN003627): Average values per metabolite and experimental factor (Units:peak area)

Metabolite structureAll dataF1F2F3F4
2/3-phosphoglycerate
145845635.73 163796652.40 141970044.90 104234353.72
2-hydroxyglutarate
55749760.92 51975181.17 81546945.82 50047546.50
2-oxoglutarate
101721481.40 113062823.60 226723741.93 167557194.73
3-phosphoserine
3581443.82 5311124.31 19951802.39 19691298.03
4-hydroxyphenyllactate
23069489.44 20467907.57 24365053.58 17140146.13
4-hydroxyphenylpyruvate
16107784.16 12297286.85 7611765.69 6806938.65
4-hydroxyproline
332071291.10 392141708.30 394975097.13 362295021.97
6-phosphogluconate
7731954.27 10457583.30 13374991.01 8457895.63
acetyl-CoA
5651420.88 8632668.80 8747153.54 6272462.29
aconitate
16973790.82 21429243.93 47726978.73 40526542.46
adenosine
15681468.70 16348215.93 10624693.23 10240139.37
adenylosuccinate
6329194.09 16779979.77 62433.64 75787.67
ADP
103468805.69 105605181.72 112589718.13 99201962.96
ADP-ribose
3704472.86 4320972.07 1938167.40 1646584.34
alanine
693629303.17 798196041.37 912174510.07 801676147.30
AMP
54915565.43 68397925.86 36345002.22 42908037.40
arginine
2048484852.00 2331820153.67 1804831612.67 1351374762.00
argininosuccinate
395232875.43 397520076.43 5972773.33 4945229.02
asparagine
41920633.18 53536435.26 30955627.09 29787709.97
aspartate
232078687.93 331240941.03 1593239710.00 1356401437.33
ATP
640622555.73 745538265.53 859254770.43 639145641.37
beta-alanine
196958193.73 339852144.10 229754115.13 133519174.77
betaine
1995499052.67 3519633344.00 4624838269.67 2396910314.00
carnitine
713472419.60 1475760795.33 1294541845.33 672150236.93
carnitine C14
545413.33 3420918.78 1384398.05 502718.59
carnitine C14:1
4857977.09 8809952.11 6439794.18 3679309.28
carnitine C16
1985172.07 7157331.69 2690502.73 1066774.08
carnitine C16:1
499022.37 4497053.63 1501281.27 610343.45
carnitine C2
1079929330.17 1922757160.00 679828384.33 453046397.20
carnitine C3
21929672.23 33609127.07 325588473.67 124773644.83
carnitine C4
157575456.73 326907883.77 608134298.03 363787417.87
carnitine C5
13487501.01 19404039.00 57792276.83 21237703.71
carnitine C6
5575536.42 10792530.54 4587284.33 3635431.36
carnosine
18867937.29 25132605.28 20457960.78 13622172.18
CDP
11358289.98 14973341.22 21409574.41 15683847.06
choline
2105267870.67 4030347322.00 619392575.50 326144098.13
citicoline
12957166.73 13962119.25 7867691.22 3615057.73
citrate
1035189228.00 1290060659.33 1785117381.67 1755742231.00
citrulline
42137413.11 43147346.34 28953341.46 33176182.51
CMP
2572755.34 4492380.48 4708649.04 3610204.84
CMP-acetylneuraminate
20569627.20 23842158.11 19011057.34 9566215.55
Coenzyme A
9091929.13 7902545.70 5372248.95 2800542.60
creatine
20179037344.67 25067917892.33 23629608939.00 18685393182.33
creatinine
1007535038.40 1381128050.67 1144323209.00 768203269.90
CTP
40708369.43 61063091.74 88883298.39 55171023.97
cyclic ADP-ribose
29097047.72 35208560.67 29088997.28 19999955.21
cyclic AMP
1178384.81 1725528.44 1558007.23 914892.84
cystathionine
8585093.51 8035857.44 22528133.40 56551678.24
cysteate
4680390.31 14053305.21 1527417.77 1112479.17
cysteinylglycine
47764561.07 50987978.12 17656038.36 25112401.30
cytidine
6258177.21 10485755.11 11753015.15 6711161.92
cytosine
7241084.21 10504872.59 12080284.19 7831253.85
dCTP
1005509.37 1488542.06 4234971.40 2662956.54
deoxycarnitine
320857696.70 529785037.07 257147191.03 162116429.03
dihydroorotate
37409670.38 43378687.74 23270576.63 14281245.34
dihydroxyacetone phosphate
155952825.17 190291229.30 127892604.53 103280468.20
dTMP
518958.01 502344.94 796217.63 744085.56
dTTP
6011421.16 7824951.00 16605710.98 11128656.19
flavin adenine dinucleotide
4775402.14 6400133.55 3603825.32 2750911.83
fructose 6-phosphate
41492079.04 51856929.37 37750091.50 20387875.76
fructose bisphosphate
143421718.73 175660967.03 107609016.15 63907384.26
fumarate
1320331730.67 1834088611.00 132333383.03 99624329.92
gamma-glutamylcysteine
142949388.37 263808134.63 8558808.58 10427844.93
gamma-glutamylglutamate
6058519.72 8402273.97 7801758.62 7852265.15
gamma-glutamylproline
65457319.35 85761483.18 55923180.38 65277397.21
GDP
26776443.03 32830678.01 21835287.80 16372576.29
GDP-fucose
6943310.85 9197900.92 4542496.37 3007593.67
GDP-glucose
3418537.83 4106263.51 3211416.90 1879727.50
gluconate
1127832322.53 1094256376.33 1550845704.33 1138034340.00
glucose
248342274.63 307959608.73 316049192.27 205334568.37
glucose 6-phosphate
66493731.51 100012009.72 58068084.97 36070721.25
glucuronate
11788405.98 14562148.51 6561448.17 5555247.56
glutamate
1454311765.33 1571726769.33 4374177682.33 2874910790.33
glutamine
6132616875.33 7073456544.67 5422944203.00 5313573662.67
glutathione reduced
6467601057.00 7199831494.00 2838450527.67 3680216937.00
glyceraldehyde 3-phosphate
100952935.44 114625799.77 51451010.47 19295313.51
glycerol 3-phosphate
135097445.07 222697988.47 101437747.23 104899892.30
glycerylphosphorylcholine
17450850115.00 20904056210.00 21298280562.33 8574454253.67
Glycerylphosphorylethanolamine
119585588.07 189567539.63 116119648.70 44087732.40
glycine
65106856.69 87654463.07 56857524.16 38285258.46
glycylglycine
13928579.66 21834741.21 18858301.37 10453729.83
GMP
5575726.00 6788933.41 3792813.51 3249841.09
GTP
51577148.55 69633197.91 43118809.58 29596539.13
guanidinoacetate
7438451.63 11089822.24 9185421.79 5148976.97
guanosine
1998604.86 4192365.25 2126051.39 1133369.95
histidine
2616504105.67 2694968736.33 2128026216.33 2463778501.33
homoarginine
21271337.13 25560942.56 17638472.53 12928031.74
homocitrulline
3903756.56 4773998.58 4450411.32 2879023.91
homocysteine
1463154.70 1586705.71 1386902.61 1104240.67
hypotaurine
28094471.85 43772845.37 30410618.51 18913304.48
IMP
3802993.41 5090215.32 1772062.53 1716752.28
inosine
3552527.61 4619390.50 2508345.39 2143783.93
inositol
437994829.13 896218301.20 461080461.17 431142323.20
isoleucine
5147624555.67 5873521421.67 5075176911.67 3453716512.33
ketoleucine
60843224.50 77485664.19 94946103.66 46316270.16
ketovaline
8685899.48 10801138.95 13835717.42 8299171.11
kynurenine
10493543.99 12745554.01 11535109.73 7539927.19
lactate
3964307593.67 4908172039.33 2190366743.00 1080771172.17
leucine
6492563885.33 7420218497.67 5709391432.00 3996583583.67
lysine
540721337.67 698064974.17 457119512.77 280071056.87
malate
224963966.13 398916592.00 1689008241.00 1300519927.00
methionine
3912336569.67 4173946728.00 3337016871.67 3197523954.00
methylthioadenosine
365469854.10 358112157.10 424962856.47 444676928.60
N6,N6,N6-trimethyllysine
95138688.17 119896728.40 44240952.56 37319656.48
N-acetylarginine
8716543.87 9673963.41 4567630.76 4991770.79
N-acetylaspartate
7266101.92 8222300.93 94762168.55 10161145.55
N-acetylaspartylglutamate
1750984.28 2208537.54 6144161.55 5020146.57
N-acetylglutamate
6237805.45 7036352.10 36256091.32 23804012.75
N-acetylhexosamine phosphate
7490540.35 14288128.99 8699956.93 6698582.90
N-acetylhistidine
117652141.16 163853055.70 134838488.41 76620812.66
N-acetylneuranimic acid
37614620.00 37707204.18 27580102.24 20115045.80
N-acetylserine
362051767.17 593935585.53 890395723.07 742644353.40
NAD
209474468.83 249088062.23 222320821.07 153352663.80
NADH
101353190.40 149086284.90 33911229.59 11338478.64
NADP
9689249.39 10315834.94 4450416.07 2909506.68
NADPH
6249004.46 8348565.68 8279324.00 6645207.55
N-carbamoylaspartate
7084951.03 7417635.99 9746293.04 7886698.71
N,N-dimethylarginine
76319629.30 83089263.47 53005087.83 41501703.64
ophthalmate
4692832.01 3452500.62 188609373.33 77061952.19
ornithine
11455302.06 15425663.21 12764996.11 11485324.04
orotate
34543392.86 71107821.86 25018572.01 23120425.86
orotidine
7957137.77 11508104.64 31393163.94 18252256.55
oxidized glutathione
49658077.77 55942815.76 27117957.75 23691033.06
pantothenate
1026421213.83 1415903520.33 580032081.17 444678546.77
pentose phosphate
35506683.52 49028771.95 39471572.59 27521591.17
phenylalanine
6286308894.33 7000456599.00 6012284609.00 4058081411.67
phosphocholine
26127705161.33 32100403655.00 40431522035.33 32358333188.33
phosphocreatine
61648889.08 139999504.60 820796117.53 480046508.53
phosphoenolpyruvate
51502816.43 77028982.29 13111097.48 11697491.55
proline
4536182104.00 4831190989.33 12388031587.00 10639797099.00
pyridoxine
57283033.15 74671770.82 70308919.95 42268010.30
pyroglutamate
4757210536.33 6304020131.00 4902032466.00 3215403517.67
pyruvate
75304828.99 119589985.60 137096840.28 78972255.61
S-(2-succinyl)cysteine
188896031.47 206126377.57 326840.40 347947.07
S-adenosylhomocysteine
7118483.53 13109409.43 8729341.00 5380406.23
S-adenosylmethionine
434763216.87 432253488.77 374767280.80 377603788.20
SAICAR
9280874.93 41321343.91 371369.26 247905.07
sarcosine
13807847.80 19625903.19 10502495.91 3092225.72
sedoheptulose 7-phosphate
11573914.99 10210374.77 16711284.46 8134873.78
serine
249269867.27 333664673.13 220556424.63 161508888.50
S-Succinylglutathione
117364193.27 131124440.77 1232043.82 1667221.46
succinate
720929187.37 855039279.37 139002289.53 65514712.04
succinyladenosine
6635966.87 7885560.89 46375.51 61433.06
taurine
3432275313.00 4821448451.00 4071633513.67 2849411001.67
threonine
2884944347.33 3564997671.00 2552619976.00 1997944775.33
tryptophan
1008252417.17 1195276399.00 920655307.80 563873987.27
tyrosine
4532558853.00 5136219488.33 4238940088.00 2890187024.33
UDP
69653387.00 90630470.52 110617908.63 85463948.51
UDP-GlcNac
695971040.27 1002661458.73 617319975.73 469441892.90
UDP-glucose
282521075.67 393394966.23 375889065.63 274622541.40
UMP
24271009.87 54480311.70 20768031.44 18867813.79
uric acid
33533009.48 56711504.53 30611641.80 18611023.68
uridine
2942334.16 4892855.13 3498752.76 2184885.33
UTP
168128605.23 275359574.30 332948555.03 202647413.27
valine
2655212435.67 3040324792.00 2521986510.00 1670832623.00
xanthine
74706849.57 96173333.96 80409075.09 49643334.93
xanthosine
1676216.38 2112928.15 1568935.68 1012912.28

Factors:

F1Genotype:Fh1-/- CL1 | Treatment:Cas9
F2Genotype:Fh1-/- CL1 | Treatment:sg1Hira
F3Genotype:Fh1 fl/fl | Treatment:Cas9
F4Genotype:Fh1 fl/fl | Treatment:sg1Hira
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