Data for ST002375   

(Analysis AN003870): Average values per metabolite and experimental factor (Units:AUC)

Metabolite structureAll dataF1F2F3F4
1-Methyladenosine
68680.45 147150.15 109717.17 120010.21
1-Methyl-Histidine
1459191.94 2242190.69 1261085.08 1857462.40
1-pyrroline-5-carboxylate(P5C)
250147.40 324940.48 299812.16 362111.93
2,3-Diphosphoglyceric acid
76936.38 82928.08 66481.08 85443.52
2-Aminooctanoic acid
832655.90 874033.67 513869.67 519559.57
2-Hydroxy-2-methylbutanedioic acid
6129907.60 7744028.26 5624811.03 7262027.08
2-hydroxygluterate
1648189.38 2511874.64 2525067.24 3455473.93
2-oxobutanoate
21229623.60 19564365.12 20692880.88 20828502.92
3-phosphoglycerate
440962.36 439058.93 420610.86 394599.88
3-phospho-serine
19335.69 47688.06 119403.68 1085390.74
4-aminobutyrate
119466.18 156378.75 129806.45 181492.52
acetoacetate
21371246.48 20347593.78 19874872.09 20674007.42
Acetylcarnitine DL
11727060.49 16243603.28 25733273.61 26452818.84
acetyl-CoA_pos
113178.22 167791.45 120488.29 134026.36
Acetyllysine
401835.27 474738.67 388361.14 456521.23
aconitate
1814162.76 2403573.25 2070367.97 2581911.30
adenine
372524.28 1014390.58 505737.42 859283.49
adenosine
228633.94 432775.77 422894.22 450914.44
ADP_neg
1457399.95 2464702.08 1986849.93 2366503.42
AICAR_aminoimidazole carboxamide ribonucleotide
2232544.60 113503.58 303441.84 53025.51
a-ketoglutarate
15337129.72 15230908.01 14901708.86 15073770.19
a-Ketoglutarate_PH
204533.52 161708.21 166595.46 181748.06
alanine
6913642.53 3241690.23 4376248.39 4093545.29
allantoin
656647.46 878075.34 715280.54 824662.96
AMP
2442804.89 3247630.53 2905476.13 3272201.78
anthranilate
129728.20 167124.27 136558.94 135667.26
arginine
2511903.10 2432086.64 1980391.33 2635985.18
asparagine
3824787.54 4512632.02 4152589.26 4439726.33
aspartate
68139430.43 89580378.37 29579509.88 40445803.55
ATP_neg
15998484.82 24486299.69 21621031.14 23403262.59
beta-Hydroxybutyrate
1330430.75 2283671.01 1765581.08 2155879.91
betaine
375355554.33 393057762.47 351048764.60 361829145.00
Carbamoyl phosphate
7770456.29 3187803.81 8245905.87 7650247.23
carnitine
20829813.45 23042914.85 18845697.18 20865016.80
cholesteryl sulfate
134603.45 121792.25 113757.92 115389.78
choline
111447215.40 194565376.20 145215040.63 176075747.30
citrate
8804646.18 10895107.19 7765909.32 12490499.88
citrate-isocitrate
18120903.39 24123330.41 17389777.58 26444002.90
citrulline
165455.33 183491.44 150271.92 161782.70
CMP
251039.19 305631.79 249532.21 252129.94
creatine
6144763.78 7381055.95 5621941.80 7341955.03
creatinine
1214716.84 1529526.58 1345910.09 1394545.50
CTP_neg
877070.77 932230.11 620939.67 864876.61
cyclic-AMP
103309.13 117643.99 62861.86 71063.66
Cystine
145084.25 198449.08 162257.22 164586.93
cytidine
435099.75 534704.08 355571.68 563321.66
cytosine
276463.80 248110.47 270094.45 262552.78
dAMP
192186.47 236292.24 173948.25 233866.12
deoxyribose-phosphate
1110194.87 1482374.53 1159389.83 1406813.86
deoxyuridine
24466.08 56187.19 27236.13 48218.30
dGDP_neg
1493424.16 2334668.50 2024512.17 2377626.93
dGTP
15239504.63 21763091.94 20970654.55 22285730.99
dimethylglycine
10856072.64 18898128.57 14124435.76 16753152.74
DL-Pipecolic acid
66360553.39 93714719.04 96737346.69 107218267.50
D-sedoheptulose-1-7-phosphate
1073873.12 2435856.70 511793.13 534293.33
FAD
38032.68 36906.48 37880.32 34493.16
fructose-1,6-bisphosphate
2644145.71 7102347.30 800932.97 611013.42
Glucose_neg
1040519.09 1255049.82 1234649.11 1247221.49
glutamate
60214044.50 91041594.27 96648176.28 114368226.83
glutamine
45629106.02 57092502.67 58634395.77 62904397.62
glutathione
4203274.49 4797930.93 4185057.01 4835902.19
glutathione disulfide_neg
8407459.89 12449007.42 11423006.24 13261519.29
glutathione disulfide_pos
2854522.88 4176036.36 3912557.73 4420881.31
glutathione_neg
2661556.78 2876298.87 2810712.23 3397205.26
Glycerophosphocholine
19048104.95 44529881.02 49569690.44 50221144.21
glycine
27483.55 28370.68 25374.64 30264.61
glycolate
1793187.10 1773509.55 1812513.19 1863089.05
glyoxylate
3549221.89 3592388.75 3665788.20 3792032.91
GMP
104619.97 187530.55 173264.78 185997.68
GTP_neg
709749.31 1138819.82 882116.31 985823.63
guanidinosuccinate
146195.89 162072.12 146576.85 166085.99
guanosine 5-diphosphate,3-diphosphate
53768.10 70783.98 35436.02 43429.24
hexose-phosphate
2864324.04 5425005.97 2143331.76 2090301.26
histidine
1549211.17 2068686.47 1652760.42 1880273.06
homocysteine
260734.20 364752.73 127375.27 153768.39
hydroxyphenylpyruvate
52984.22 67570.36 84367.91 76157.15
hydroxyproline
7978600.76 10479285.84 9437243.63 11019376.01
IDP_neg
185898.93 317984.06 279353.83 324270.17
IMP
870961.22 793372.62 876128.49 993259.90
inosine
471901.07 443060.31 893093.54 980964.78
isocitrate
1129786.38 1154620.30 1551966.98 1095789.69
Itaconate_pos
55105.15 73226.62 68576.64 80605.31
lactate
22077305.63 39809800.99 22951614.08 22903988.95
L-Cys-Gly
13139.61 17504.88 13498.64 23154.26
leucine-isoleucine
29208651.75 39504142.46 32976058.68 37461352.38
lysine
129466.07 126330.39 113681.37 136330.75
malate
26359823.46 42093283.21 39139191.71 36739813.60
Maltose
75843.06 95179.31 158239.62 59178.07
methionine
741948.67 815488.03 804922.30 848108.39
Methionine sulfoxide
186508.60 237190.43 184804.05 213101.60
Methylmalonic acid
5133747.51 5641059.25 5636595.26 5702697.77
myo-inositol
3136927.19 3481766.87 5134841.21 5722131.03
N6-Acetyl-L-lysine
509574.03 604088.71 500609.30 583516.83
N-acetyl-glucosamine
78147.42 80349.53 64934.06 74495.26
N-acetyl-glucosamine-1-phosphate
349079.23 330535.55 420699.11 411956.94
N-acetyl-glutamate
2527288.17 2032384.07 99478.43 1903436.85
N-acetyl-glutamine
151555.61 217755.68 168931.90 211617.63
N-Acetyl-L-alanine
574824.30 674571.05 529585.09 626323.28
NADH
150769.88 285717.35 66100.04 70775.61
NAD+_neg
2782507.70 3890810.01 2784980.02 3034854.59
NADP+_neg
793112.66 1055239.27 821568.88 952297.76
NAD+_pos
2728498.24 4274320.95 2861739.15 3189995.20
NADP+_pos
835745.14 1063721.61 840872.92 1019141.04
Ng,NG-dimethyl-L-arginine
239534.34 312145.05 222553.73 270106.23
nicotinamide
1702018.98 2941190.22 1631265.37 2034722.18
O-acetyl-L-serine
129060.95 188464.11 151948.52 177512.45
octulose-monophosphate (O8P-O1P)
446307.82 895793.66 218610.39 247267.60
ornithine
4657604.95 6435726.14 4122566.28 5243695.57
p-aminobenzoate
166311.65 132706.22 157175.40 155345.76
pantothenate
21954525.45 33945039.09 18838546.57 26993097.06
phenylalanine
3440307.72 3895498.25 3744026.70 4002367.31
Phenyllactic acid
38364.73 37323.21 46796.62 56896.94
Phenylpropiolic acid
3417403.46 4254388.38 4444085.07 4654973.02
Phosphorylcholine
17581730.13 41509084.79 53508873.09 60147123.50
p-hydroxybenzoate
3028814.81 3218444.23 2447840.55 3103286.91
proline
33041354.66 35525529.91 30006130.91 30013212.42
Pyroglutamic acid
1450252.74 2137639.59 1643539.67 1800993.54
ribose-phosphate
1304669.00 562229.94 294222.37 305653.41
S-adenosyl-L-homocysteine_neg
113429.33 188125.25 117201.37 143811.14
S-adenosyl-L-homoCysteine_pos
60437.42 118045.69 50883.44 81291.42
S-adenosyl-L-methionine
2112636.76 2172088.90 1721029.14 2324615.42
sarcosine
3466999.36 1718844.41 2205713.82 2035807.21
serine
725255.30 4539529.32 1699072.74 7369421.35
shikimate
110573.54 109957.42 104019.39 118782.64
S-methyl-5-thioadenosine
3653378.65 6330703.86 3024420.33 4787436.77
sn-glycerol-3-phosphate
283918.50 536123.22 649556.00 720912.19
spermidine
3277681.80 3183506.10 5411045.06 2925681.24
succinate
5397550.37 6123856.91 5749215.77 5902288.45
taurine
197165485.50 229717691.17 220960099.37 234310709.87
Taurodeoxycholic acid
83017.14 79322.35 86472.58 91044.78
thiamine
1294064.09 1551917.74 1765776.98 1712947.28
Thiamine pyrophosphate
101621.85 108231.12 86683.68 104383.74
threonine
3855043.14 4027095.83 3959230.35 4088304.63
thymidine
17720.71 116885.02 39061.17 63577.05
thymine
187721.59 176009.67 155841.80 212011.42
trehalose-sucrose
105802.80 135679.91 168071.31 82063.75
tryptophan
218104.16 332287.14 461539.86 481064.34
tyrosine
940565.58 1029172.33 958084.23 980696.61
UDP-D-glucose
1419973.39 1221143.89 921585.83 993300.38
UDP-N-acetyl-glucosamine
68492.17 63185.95 62794.09 61179.65
UDP_neg
1306638.86 1120018.62 815726.46 954423.74
UMP
97840.12 122255.93 70073.03 100298.84
Urea
397118679.67 358916278.57 371633810.87 362921336.67
uridine
291458.79 234573.22 172532.98 244795.66
UTP_neg
13825712.94 10665016.54 7956644.31 8908157.95
valine
165013.14 167849.93 162997.74 202769.92
xanthine
1350904.71 2013191.17 1548772.92 2134952.50

Factors:

F1Treatment:GOT1 KO_Serine-free
F2Treatment:GOT1 KO_Serine-replete
F3Treatment:WT_Serine-free
F4Treatment:WT_Serine-replete
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