Data for ST002457   

(Analysis AN004009): Average values per metabolite and experimental factor (Units:concentration)

Metabolite structureAll dataF1F2F3
10-HAD
494620.04 375332.79 530017.95
10-Hydroxydecanoic acid
272823.16 226076.60 356050.02
14-Methylhexadecanoic acid
2377608.74 2544854.85 2386692.90
1-Aminocyclopropanecarboxylate
535166.97 687729.90 631426.51
1-Methyladenosine
40944932.84 49513528.91 31605347.76
2,4-Dihydroxypteridine
315018.45 211153.57 213545.65
2-Acetamido-2-Deoxy-Beta-D-Glucosylamine
340635.10 376331.79 624401.76
2-Aminoadipate
14072099.00 31654496.21 20202584.90
2-Aminoisobutyrate
13545095.16 20220923.48 17750966.16
2-Aminophenol
68022.93 85292.59 74209.53
2^-Deoxy-5^-Adenosine Monophosphate (dAMP)
851218.06 311764.81 740115.23
2-hydroxy glutarate
8523158.19 7065397.94 6679632.68
2-Hydroxyhexadecanoic acid
1124155.54 1012746.57 1043597.22
2-Methylmaleate
71408210.79 73146694.17 70219873.27
2-Phosphoglycerate
1966491.66 4059816.09 2778578.52
3-(2-Hydroxyphenyl)Propanoate
134449.46 99028.55 183589.19
3-(4-Hydroxyphenyl)Pyruvate
1007610.56 2502521.66 3105360.85
3-Hydroxybutanoate
1770625.94 2007404.87 1941320.22
3-hydroxybutyric acid
9651919.47 12078101.43 12807542.96
3-Hydroxymethylglutarate
3343498.14 3602573.49 4412367.90
3-Hydroxyoctanoic acid
922486.70 944898.69 1099830.30
3-Methyl-2-Oxovalerate
1737764.15 2157295.06 2281922.11
3-Methyl-L-Histidine
39003272.35 57057069.45 56208731.78
4-Acetamidobutanoate
3008326.44 6049832.31 5636259.83
4-Guanidinobutanoate
28122359.78 35353264.31 31496449.89
4-Imidazoleacetate
86827185.80 106752935.21 133370746.21
4-Pyridoxate
72610748.70 86775396.21 66197204.20
5-Aminolevulinate
971950.62 534057.35 499469.41
5-Hydroxylysine
254109.33 601291.43 753505.92
5-Methylcytosine
666105.67 885146.56 777609.35
5(Z),8(Z),11(Z)-Eicosatrienoic Acid
2256322.74 2337388.16 2054681.72
6-Carboxyhexanoate
1910296.18 1777315.52 877468.83
9-Decenoic acid
234476.43 234979.01 207596.09
Acetylcholine
320232.68 397970.03 490631.26
Acetyl CoA
242904.08 295980.07 216459.15
Acetyl-L-carnitine
1572192510.00 1886456997.64 1696933028.38
Adenine
52597158.08 68294067.90 64118148.42
Adenosine
396567372.60 186641314.27 340069765.20
Adenosine 3^,5^-cyclic monophosphate (cAMP)
121117.03 132648.77 104159.89
Adenosine 5^-Diphosphate (ADP)
74087069.77 80846781.89 72224362.24
Adenosine 5^-triphosphate (ATP)
10893074.76 14470255.30 9140209.07
Adenosine Diphosphate Ribose
22698216.18 25137677.74 21073234.21
Adenosine-Monophosphate (AMP)
357546746.89 314225049.11 371505803.90
Adp-Glucose
823672.03 794973.10 740037.92
AICAR
423099.06 363423.77 400850.76
Alanine
288316774.07 345407096.55 320726628.66
Alanine-IS
36763427.64 36865803.15 37011141.26
Allantoin
5673175.38 7788099.59 7821922.63
all-cis-4,7,10,13,16-Docosapentaenoic acid
2302921.06 2744144.58 2544182.08
Allothreonine
433010042.96 518365275.85 484524102.20
Alpha-Hydroxyisobutyrate
11029654.15 12220211.93 13053394.62
Aminoisobutanoate
15768005.44 21978436.69 20026095.93
Arachidic acid
765770.84 1017402.69 690140.05
Arachidonic acid
28207824.01 29008059.35 28632129.34
Arginine
129932674.66 163436622.85 139378517.97
Argininosuccinate
2659850.93 3221695.47 3029078.68
Asparagine
92419875.62 94161435.47 102908822.48
Aspartate
107645523.53 150621603.10 117847909.65
Behenic acid
131515.84 480351.42 289638.41
Beta-Alanine
23886235.07 27485913.72 31885557.45
Beta-Glycerophosphate
19859741.91 31103874.37 25653655.56
beta-Hydroxyisovaleric acid
788416.34 698528.94 941894.40
Betaine
7162046774.43 5567093824.27 5172015213.00
Beta-Nicotinamide Adenine Dinucleotide
11469403.28 17174108.40 14243687.35
Butyryl-L-carnitine
163924431.09 121880255.17 137616546.18
Carnitine
4859137133.29 5369242358.36 5218747223.75
Carnosine
1113136.79 1319674.97 854539.66
CDP-Ethanolamine
16194277.80 13258287.44 14106209.06
cis-11-Eicosenoic acid
1759304.68 1546070.13 1405470.13
Cis-4-Hydroxy-D-Proline
187350113.44 297264743.33 315134717.01
cis-5-Dodecenoic acid
261686.52 228681.16 245367.16
cis-7,10,13,16-Docosatetraenoic acid
4225269.05 5169226.89 4429904.15
cis-Aconitate
214807.32 301201.58 250971.89
Citicoline
23139407.50 24384732.32 30544719.76
Citrate
67042002.63 81435426.90 80890905.40
Citrulline
56858623.80 112675821.39 84110417.57
Coenzyme A
2432722.01 2471757.47 2299776.90
Corticosterone
78497.79 191339.44 161542.15
Creatine
7928901911.57 9253822265.82 8621989694.12
Creatinine
76154165.79 118443189.59 101372745.52
Cyclic AMP
518954.70 508514.36 460798.78
Cystathionine
285455.78 612701.55 420127.65
Cystine
7646737.26 9529689.80 17233662.34
Cytidine
53793296.97 39047127.90 46206377.94
Cytidine 2^,3^-Cyclic Phosphate
626618.64 2289965.13 67084.66
Cytidine Diphosphate (CDP)
1204204.60 1473786.94 1088232.39
Cytidine Monophosphate (CMP)
15934944.54 10397427.25 9812288.36
Decanoic acid
2736122.89 2050462.09 2957052.05
Deoxycarnitine
225838087.91 201713182.55 218228331.44
Deoxycytidine
4522068.27 7697270.22 5457243.39
Deoxycytidine-Diphosphate (dCDP)
14436.39 27931.82 26972.09
Deoxycytidine Monophosphate (dCMP)
447610.15 222143.18 231077.89
Deoxyguanosine
396567372.60 186641314.27 340069765.20
Deoxyguanosine diphosphate (dGDP)
80379759.08 89035081.27 77405740.89
Deoxyguanosine-Monophosphate (dGMP)
357546746.89 314225049.11 371505803.90
Deoxyguanosine triphosphate (dGTP)
11456665.29 14781807.38 9574594.86
Deoxyribose
311631.95 314721.38 410453.38
Deoxyuridine
157021.71 267381.96 304868.31
Dethiobiotin
647101.67 977550.31 957593.07
D-Glucosamine 6-phosphate
290068.54 209623.75 230145.47
Dihydrobiopterin
1814849.60 1415035.33 1532751.49
Dihydronicotinamide-adenine dinucleotide phosphate (NADPH)
75270.17 128390.04 54425.80
Dihydroorotate
735843.57 774653.93 618195.77
Dihydroxyacetone Phosphate (DHAP)
447183.03 312102.45 325518.76
Dimethylarginine
13282176.08 24149205.72 20963111.81
Dimethylglycine
124687904.97 132211911.53 145092418.84
Docosahexaenoic Acid
13887765.61 15666438.74 14484471.05
Docosatrienoic Acid
123919.07 156179.36 82473.70
D-Ribose 5-Phosphate
6517601.35 4333619.17 5330400.22
D-Sedoheptulose
146567.98 169416.38 191336.00
Eicosapentaenoate
1642604.26 1578699.44 1806157.54
Erucic acid
297962.33 372668.24 270179.08
FAD (Flavin adenine dinucleotide)
2668246.87 2649847.68 2493143.36
Fructose 6-Phosphate
3394227.29 4177522.06 4273201.19
Galactosamine
671435.79 637794.82 632912.38
Galactose 1-Phosphate
4021513.69 5011916.33 5094394.26
Galacturonate
2965381.76 13052412.69 19673178.21
gamma-Glutamylcysteine
7540417.56 12193317.79 16379959.68
Glucosamine
670563.84 637731.32 632872.41
Glucose
20509065.88 19939788.57 20199277.81
Glucose 6-Phosphate
3558067.73 4325941.97 4313057.56
Glucose-IS
19023547.92 19177897.78 19141060.83
Glutamate
1879297510.86 2196636707.82 2113825155.38
Glutamate -IS
158616405.01 151565610.56 155507103.43
Glutamine
1498050625.57 2297015458.00 1706488006.50
Glutamine - IS
173821107.86 147932621.20 163619752.79
Glutarate
789490.63 1198640.76 1198708.53
Glutarylcarnitine
955579.06 3520613.93 2365807.14
Glutathione disulfide (GSSG)
7007103.56 3845255.77 3719110.66
Glutathione Reduced (GSH)
255022340.60 263067096.05 213280449.11
Glyceraldehyde 3-phosphate
4117889.68 1755951.84 2082603.61
Glycerol
1986634.36 2019235.13 2378226.95
Glycerol 3-Phosphate
18653162.94 29440906.65 24321465.11
Glycine
43175162.46 47026301.18 50992316.72
Glycolate
5493024835.00 5461865615.18 5471205153.00
Guadinoacetate
108716868.65 167906413.76 146123274.25
Guanidinoacetate
108716868.65 167906413.76 146123274.25
Guanidinosuccinate
33601.80 177473.50 186893.43
Guanine
28153352.62 22283382.01 23045065.45
Guanosine
25866648.17 13884839.08 21153436.88
Guanosine Diphosphate (GDP)
1734225.66 2271639.66 1983882.41
Guanosine Diphosphate Mannose
904848.29 862100.24 851492.15
Guanosine Monophosphate (GMP)
48270277.79 41069609.27 39936789.59
Gulonolactone
84788.88 225468.71 196390.53
Hippurate
10679578.63 10663092.67 10887761.60
Histamine
48123877.82 68668239.29 47411870.57
Histidine
299841483.11 285896986.43 376221068.15
Homocysteine
2442875.32 4779161.92 2787101.00
Homoserine
433010042.96 518365275.85 484524102.20
Hydroxyproline
187350113.44 297264743.33 315134717.01
Hypotaurine
151876890.71 136731119.13 148257060.96
Hypoxanthine
379806437.19 288882310.61 310357218.40
Indoxyl Sulfate
14405463.35 10796241.04 14840932.90
Inosine
68605609.73 44556442.14 59587859.93
Inosine-Monophosphate (IMP)
30136980.92 19724941.17 24034337.19
Isoleucine
207874673.69 292662646.52 303519387.11
Kynurenate
2329963.83 8350592.80 4895956.56
Kynurenine
21625867.01 26054779.95 28076592.30
Lactate
539196489.77 507390859.52 501976210.55
Lactate -IS
49498240.64 49059623.85 49108288.61
Lauric acid
9179911.15 3113515.28 3898265.81
Lauroylcarnitine
1534930.96 2172558.01 1905140.64
L-Cysteic Acid
2231994.05 2179068.18 2327167.75
L-Dopa (3,4-Dihydroxyphenylalanine)
620294.61 434118.60 319770.91
Leucine
690388624.76 772745398.25 943404003.31
Lignoceric acid
341415.77 763299.77 413324.97
Linoleic acid
34031364.26 25349730.50 22805220.64
Linolenic acid
2226176.40 1282927.34 1424562.00
Lumichrome
103623.88 84438.23 135491.26
Lysine
179208680.50 203471485.06 216863664.50
Malate
216421835.00 227258505.18 256296339.84
Mannitol/Sorbitol
11963800.69 16321192.94 133924730.27
Methionine
565717076.79 701009398.78 670676004.34
Methylarginine
1607169.44 2160216.43 2138886.94
Methyl Galactoside
1290447.35 510822.54 950967.25
Methylthioadenosine
15840773.00 15514155.88 15857035.37
Methyl Vanillate
12354709.87 10295248.47 11841224.71
Mevalonate
333572.57 427726.35 577756.31
Monoethylmalonate
1187249.04 935304.70 1009735.38
Myo-Inositol
39234066.84 41857801.92 41883264.08
Myristic acid
11553219.19 11867113.07 12437801.54
Myristoleic acid
1576684.72 1095034.22 1648928.46
Myristoyl-carnitine
1588733.31 2063307.62 1716157.68
N6-(Delta2-Isopentenyl)-Adenine
55071453.52 63453721.94 58320320.07
N(6)-Methyllysine
3968464.96 5619335.26 5047168.27
N-Acetylalanine
2071729.57 1879090.16 1934213.64
N-Acetylasparagine
340482.65 891581.77 619052.05
N-Acetylaspartate
1171578.67 1189542.09 1290039.07
N-Acetylcysteine
273090.73 421901.33 185206.87
N-Acetylglucosamine
5952483.28 11891195.47 13546015.89
N-Acetylglutamate
628908.46 691923.85 537094.51
N-Acetylglycine
276146.61 409863.02 356134.37
N-Acetylleucine
296508.57 1207281.59 792164.00
N-Acetyl-L-glutamine
2710220.72 22480577.36 12392926.87
N-Acetylmethionine
512460.18 888715.82 612775.11
N-Acetylneuraminate
12409894.72 51127652.18 51249148.38
N-Acetylphenylalanine
227114.82 308347.93 316029.46
N-Acetylputrescine
5968043.81 12797595.34 6208913.47
N-Acetylserine
6186602.67 6100550.77 6946055.52
N-Alpha-Acetyllysine
3207222.16 9405447.79 8662494.88
N-Amidino-L-Aspartate
33601.80 177473.50 186893.43
Nervonic acid
196654.69 463932.56 309767.43
N-Formyl-L-Methionine
113954.07 322900.32 223775.68
Nicotinamide
563579474.84 467925445.18 496811980.71
Nicotinamide adenine dinucleotide phosphate (NADP+)
311220.60 525740.08 335538.19
Nicotinamide adenine dinucleotide reduced (NADH)
2254922.19 3331766.73 2524714.51
N-Metyl-Alanine
95162761.89 111043762.05 125549829.66
Norvaline
452793910.97 484494700.18 543105088.75
Oleic acid
60974742.50 51238591.55 50700271.05
Omega-Hydroxydodecanoate
65640.98 78931.60 95339.69
O-Phosphoethanolamine
666937926.20 593180317.78 565462661.84
O-Phosphoserine
115119.77 206077.56 114136.68
Ophthalmate
198097.94 667375.98 419282.28
Ornithine
21196061.66 24288743.11 26463503.64
Orotate
6516027.17 5800360.26 6229555.32
O-Succinyl-Homoserine
622745.59 1501242.46 1659757.16
Oxoglutarate
2906780.65 4908428.82 5882964.18
Oxoproline
21097237.94 30679329.68 36740169.37
Palmitate
217813508.31 272440749.07 221026351.45
Palmitoleic acid
16358145.19 13316813.84 15807668.96
Pantothenate
74675597.12 95625736.36 91198413.54
Pentadecanoic acid
4196790.91 3748389.72 4572478.12
Pentanoate
758581.33 645658.47 722525.10
Phenylalanine
655082524.21 779088846.49 737036486.70
Phenylpyruvate
12834.79 26229.17 71372.81
Phosphocreatine
6670965.20 24050225.10 11068755.12
Phosphoenolpyruvate
1176366.72 2333241.60 1826389.31
Phosphorylcholine
17655621.02 12035149.42 13010411.25
Phosphoserine
115119.77 206077.56 114136.68
Pipecolate
81459972.70 102376038.14 107383563.55
Proline
871336477.90 1036150714.23 1117680633.05
Propionyl-carnitine
38600955.65 76275398.08 67720357.11
Pterin
154518.95 124237.10 109820.45
Pyridoxal
737720.61 767267.92 768878.09
Pyrophosphomevalonate
114907.97 109345.30 74479.25
Pyruvate
18251095.29 12435962.24 17590029.04
Pyruvate - IS
6579037.88 6320945.15 6362733.74
Quinolinate
409763.54 467260.05 427474.38
Quinoline
184938.98 482730.87 234286.74
Raffinose
5145571.14 3477908.75 3141386.71
Retinoate
263539.07 384005.53 422108.57
Rhamnose
22157632.95 20691469.43 23550844.96
Riboflavin
917528.92 1052903.22 701486.03
Ribose
921250.44 1192908.40 1291000.28
Ricinoleic acid
1845178.18 1866124.53 1852609.70
S-Adenosylhomocysteine
4572292.70 4110407.87 4494040.00
S-Adenosylmethionine
6872250.11 8100041.81 7723104.00
Sarcosine
26118585.03 25180223.56 25233471.53
Sedoheptulose-7-phosphate (D)
762106.12 850828.37 913124.02
Serine
48038420.66 54551244.17 55677952.83
Serotonin
1617482.39 517296.34 2165166.47
Sn-Glycero-3-Phosphocholine
3065217938.57 2393127520.18 2131175995.75
Sphinganine
867842.03 1231268.36 647713.41
Sphingomyelin
939799.56 1338365.68 1102438.98
Stachydrine (nv)
148407311.59 115626518.91 174019101.56
Stachyose
3181394.46 1912988.32 1481792.89
Stearic acid
105448709.12 141132322.90 111415721.43
Succinate
36052507.82 39371854.76 39752656.94
Succinyladenosine
1423034.96 2093341.69 2352458.90
Succinylaminoimidazole carboxamide riboside (SAICAr)
350989.13 295198.51 299742.83
Succinylcysteine
767190.31 1082888.13 1050180.65
Sucrose
5147208.00 4756204.50 5056583.95
Tartrate
58171.56 119342.05 121647.85
Taurine
1127925963.17 1068138369.96 1042777166.94
Thiamine Monophosphate
547929.40 521597.85 545590.06
Thiamine Pyrophosphate
482871.36 724242.29 584986.17
Threitol
575760.78 734454.67 750659.61
Threonine
433010042.96 518365275.85 484524102.20
Thymidine
330302.85 516000.72 393192.74
Thymidine-Monophosphate (TMP)
751919.43 272297.64 407138.19
Thymine
657937.49 782828.12 730839.06
Trans-4-Hydroxy-L-Proline
187350113.44 297264743.33 315134717.01
Trehalose
5059963.63 4682920.52 4843313.72
Tridecanoic acid
989838.46 727101.80 1154398.80
Trigonelline
119204613.17 127268606.50 126655216.41
Trimethyllysine
23335819.35 25112854.66 26189196.81
Tryptophan
356298713.34 552826977.33 381528787.02
Tyrosine
666716215.41 768535425.03 777019952.74
Undecanoic acid
526881.19 312472.42 536503.09
Uracil
6483842.59 4634622.02 6291605.11
Urate
9460398.63 10640985.04 12456308.53
Ureidopropionate
122594604.09 186207429.46 190751447.31
Uridine
15131570.50 13927048.47 18136010.57
Uridine 5^-Diphosphate (UDP)
2872874.39 3314317.33 2956450.46
Uridine-5-triphosphate (UTP)
1045097.08 1468808.79 903320.69
Uridine Diphosphategalactose
9979332.58 7536743.76 6910814.55
Uridine Diphosphate Glucose
9979332.58 7536743.76 6910814.55
Uridine Diphosphate Glucuronic Acid
2250752.34 2029308.15 1697398.23
Uridine Diphosphate-N-Acetylgalactosamine
20821656.68 18133105.85 18896515.87
Uridine Diphosphate-N-Acetylglucosamine
20821656.68 18133105.85 18896515.87
Uridine Monophosphate (UMP)
40348076.44 23810917.00 25492759.86
Urocanate
38260817.01 88614849.60 71317266.53
Valine
452838943.34 484426757.50 543123423.67
Xanthosine
1023962.11 1901962.01 1336461.44
Xanthosine-Monophosphate
14675.62 69774.29 143102.35
Xanthurenate
306999.38 882752.39 281287.52
Ximeninic Acid
2226176.40 1282927.34 1424562.00
Xylitol/Ribitol/Arabitol
3923381.31 5555328.65 4896380.72

Factors:

F1Genotype:Tsc1-knockout | Treatment:none
F2Genotype:Tsc1-knockout | Treatment:rapamycin
F3Genotype:Wild-type | Treatment:none
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