Data for ST002709   

(Analysis AN004391): Average values per metabolite and experimental factor (Units:Peak Area)

Metabolite structureAll dataF1F2F3F4F5F6F7F8
1-methylnicotinamide
689739.07 1402989.24 903197.81 1193488.18 537271.98 425577.27 432075.27 981239.18
3-hydroxy-trimethyllysine
90857.00 102802.52 78206.51 72255.79 91310.00 76656.21 57979.81 100738.02
4-aminobutyrate
41400160.65 50427608.79 34205317.43 44013754.96 46929084.87 41674752.47 31627325.53 58360138.50
5^-methylthioadenosine
2608215.83 4035162.13 2380333.63 3385272.94 2855312.18 2950528.92 2143650.85 3919073.76
6-phosphogluconic acid
3849566.10 4101338.96 2907695.97 2264503.57 8138660.56 3898855.81 3934471.50 5247512.77
acetyl-carnitine
176730059.03 186002833.40 193952497.47 180259236.07 208766583.23 219229125.93 229571595.43 217465812.23
acetyl-CoA
752558.04 937509.52 619815.43 618616.97 990198.39 730068.74 557077.71 806998.21
adenylosuccinic acid
828781.18 1404970.29 558484.14 726642.67 6599211.20 4458228.31 2615215.05 4715850.19
ADP
56473829.96 67320438.57 41430563.25 43310693.03 66042796.88 53672232.55 37524799.39 64442123.68
AICAR
294388.46 2893709.71 919356.76 1625872.17 397038.39 228636.81 124691.02 430657.23
AIR
1822074.35 1954692.43 1441645.53 2251301.57 29153937.85 20238581.77 13456120.25 32606676.10
alanine
32631926.41 38333373.50 31752711.65 28919754.93 37458179.40 41449048.05 32824594.71 39887585.96
alpha-ketoglutarate
620457737.57 955371615.57 569687515.17 803024762.10 324921932.77 472786954.57 259364949.77 678863454.10
AMP
34954645.89 45731404.37 29152688.17 31376086.06 43812191.28 39818717.25 28399666.83 41798109.74
arachidic acid
773988.25 1016029.29 732731.89 610737.09 980692.50 754758.24 836185.02 977606.15
arginine
124241053.97 150327786.33 107879325.40 121509148.33 180233153.93 162744192.27 143036605.97 148529923.83
argininosuccinate
2361209.73 2995573.64 1665381.87 1441267.29 33303823.25 26244980.76 17425444.13 24090520.74
ascorbate
3405578.48 4299778.41 1876463.41 2029568.79 375353.03 301140.26 177863.78 233405.12
asparagine
16102070.95 19230822.04 13619920.74 222757500.07 32160998.57 26744454.33 22356366.92 364985530.93
aspartate
330546169.00 369121777.70 248486675.97 214377352.37 113367179.23 77599023.51 67388491.52 75301176.48
ATP
117435884.43 168471184.93 102161287.78 96577809.20 147220751.83 105294719.29 71005941.28 140604996.27
betaine
186348055.27 191198719.97 174985226.53 160364356.77 112961218.00 99685079.72 95599393.29 109729465.30
CAIR
- 591821.11 55256.94 285470.11 - 412161.24 78820.13 512959.29
carbamoyl-aspartate
39793439.97 41998608.36 30613455.35 30594089.28 9849547.01 9295686.46 7591063.46 9962169.49
carnitine
173969689.37 206708457.03 151406362.00 147528104.03 84068165.40 78543004.06 64483995.86 95788308.48
CDP
6543823.98 9096958.96 5243551.70 5242598.66 7879339.93 6032549.01 4090582.91 7481387.75
CDP-choline
612711.70 600930.64 319610.73 302084.22 688638.24 464447.18 250761.41 476455.46
CDP-ethanolamine
229808.90 266726.86 74007.55 105164.45 126068.82 122107.49 39445.65 103451.33
choline
66359161.78 42663430.38 25277590.45 53441378.56 67285248.03 36276589.29 32170096.90 62915420.72
cis-aconitate
43025980.08 56080930.44 38886187.09 40280037.74 14071293.72 16596317.48 9173139.81 29209137.88
citrate / isocitrate
275837541.13 362488996.93 245933038.57 255123630.93 148868960.37 143830648.53 75981489.56 235328539.87
CMP
2397971.63 2867972.67 1733020.33 2049916.71 3254297.75 3123713.37 2042920.86 3409636.56
CoA
508271.08 1142466.25 603790.41 648868.06 545471.23 854602.81 544485.72 1057225.33
creatine
456204070.27 463454446.50 416001066.00 462614852.70 323578956.00 307692779.67 289721397.60 405456642.60
creatinine
2032104.77 2581438.06 2079002.73 2113721.18 1946275.94 1915890.78 1735269.57 1983975.81
CTP
11572515.16 17543419.06 8853064.70 8852749.19 13610232.65 8569859.81 5671869.92 13113877.30
cystathionine
18269.73 14727.58 15855.24 - 26062.16 15589.05 27784.92 40729.46
cysteine
273475.29 - - 646454.20 780033.01 - 217597.31 5477860.03
cysteine-glutathione disulfide
4921912.58 282157.74 1064668.82 233984.05 5816673.68 307197.82 1987195.15 293914.24
cystine
1165340.97 - 207271.72 28863.36 1098995.24 62519.05 397126.90 -
cytidine
76607.44 - - - 47560.80 - - -
dAMP
16598.64 - - - 8907.35 - - -
dATP
558888.92 752407.30 310771.99 418284.55 545348.08 362571.41 198951.25 458630.67
dCTP
130055.33 286811.92 156828.85 98784.65 169206.90 111486.64 84456.37 136646.00
dihydroorotate
18925154.95 21037338.11 14018970.05 12057089.51 5105206.95 4068540.03 3572291.83 3915598.85
dihydroxyacetone-phosphate
3990943.75 5730845.05 3654635.00 3809803.68 6212871.37 9201107.74 4130978.76 4617735.87
dTMP
406015.64 3230596.72 959531.35 1559603.78 514011.70 1702605.29 843688.12 1762251.22
dTTP
1004847.33 1360100.44 696310.13 702520.80 1017269.66 709566.29 429473.15 907446.01
FAICAR
99381.57 192970.91 - 136650.86 523993.83 349080.25 283268.54 341618.96
FGAM
93263.18 119221.57 55367.27 87893.48 3064296.03 1610580.37 934413.89 2505350.35
FGAR
660307.38 1758599.23 922841.08 956834.41 4342185.85 4587507.28 2717634.62 5176264.72
folate
1134239.10 1569681.25 501194.85 1128097.73 1691663.30 1447578.78 664132.41 1235589.29
fructose
29641590.14 36169965.97 32149570.95 24119045.53 34555200.08 33070609.06 30903223.03 35149127.04
fructose-1;6-bisphosphate
48935747.83 79054406.59 37920698.60 45270136.72 83524616.87 65386711.00 40270797.45 79926884.99
fructose-1-phosphate
1308361.56 1810916.68 314391.18 1157975.41 833317.96 579020.81 84029.30 732840.13
fructose-6-phosphate
18308917.09 22709946.55 17004259.42 14102414.82 28165314.84 25178339.51 19228902.16 28454726.57
fumarate
190493495.70 235200336.33 145003203.13 135149669.30 1047675898.07 887911132.50 686883415.90 978880033.90
gamma-butyrobetaine
11868173.33 14121857.03 11363291.25 11089999.71 7549570.35 7074012.27 6414215.10 8086178.05
gamma-glutamylcysteine
5741936.65 1373056.52 4887380.48 1685154.42 2934742.30 1090301.17 1842002.27 1950354.85
GAR
- 176030.39 28768.11 106819.38 81012.19 40915.49 60960.88 112339.11
GDP
10329836.69 13919927.44 8325405.95 8406317.12 18468599.92 13014910.63 8809694.11 16639391.03
glucose
137241703.87 172279425.20 151301663.60 112944195.76 172638289.50 152756067.97 176257483.50 120377386.30
glucose-6-phosphate
7230589.48 9318564.21 6598645.05 5729638.33 9804844.82 7601464.96 7455318.67 9371961.89
glutamate
2351584608.33 2980215284.33 2020246622.00 2312293343.33 2719003057.67 2519222824.00 1930518828.67 3057931672.00
glutamine
708016361.17 843651289.50 552511476.00 637163750.77 1539672520.67 1232414475.67 936689655.60 1234464971.67
glyceraldehyde-3-phosphate
4120556.32 5009254.41 3020009.24 3350989.05 10543722.47 7672320.77 5182006.17 9537003.68
glycerol-3-phosphate
23605674.46 39693741.00 21451320.68 25037352.72 30555648.70 28582037.33 19432400.90 30913051.03
glycerophosphocholine
1759074559.00 2046392895.33 1579880569.67 1579317256.67 2808913018.67 2628256126.67 2297284338.67 2720967151.33
glycine
1598365.88 3049203.88 1726585.69 1992647.25 5779034.96 4332131.41 3243122.19 3588821.61
GMP
3099819.85 3993826.42 2506773.81 2804086.15 5756274.67 5719980.70 3607029.34 5811986.08
GSH
860901368.83 861816595.07 731931122.10 610751298.50 1148639348.10 830025356.20 779046923.43 1028883131.23
GSSG
21097419.21 11869464.14 13663308.80 7859504.67 43168035.41 13871107.63 17754911.47 14735703.89
GTP
11482743.13 18607256.56 9564352.79 9381132.67 23606592.18 14128962.16 9171041.70 20944855.13
guanosine
120753.20 145716.20 76764.94 102807.00 152945.95 125088.25 56631.34 133348.39
histidine
99547323.74 114605200.35 77293634.06 83573503.02 166812519.17 118761594.65 95064911.75 112592879.56
hydroxyglutarate
72172840.03 97375353.26 58556079.42 81836092.93 20182786.49 26064103.90 14899432.28 41055758.57
hypotaurine
1808578.46 2158684.24 1560913.80 1403687.14 3231061.32 2690010.96 2182537.23 2947874.26
imidazoleacetic acid
8978431.92 13857734.00 9838190.66 10514940.36 8891286.49 11224245.44 8178825.55 11668103.77
IMP
1341164.15 1909970.19 1065388.23 1417102.49 9114250.23 5653273.54 3526821.61 7733263.11
kynurenic acid
89758.00 94209.78 128335.44 60304.12 62091.91 54210.00 178877.15 52816.81
kynurenine
798404.59 805528.49 2483273.65 634527.90 1554378.86 1250240.50 4019580.76 1069980.57
L-2-aminobutyric acid
4403618.99 4587565.15 3681451.47 3973739.73 4442868.40 3847247.08 2465307.21 4246544.56
lactate
106955054.46 91240438.90 78025124.25 92419639.56 115502006.53 89364164.26 97520713.55 96300803.58
lauric acid
5734409.23 5071124.28 2954722.33 3386012.89 6107214.40 3906575.59 3737866.66 5767416.46
leucine / isoleucine
544686265.37 553329582.60 393476448.83 427188426.87 1015101210.33 768226352.67 659170793.50 748571258.37
lysine
80696595.55 100416904.27 63824145.65 75386504.74 130546627.28 110542494.96 90996430.49 97492124.67
malate
1429958950.67 1666942036.00 1183923153.33 1257556099.33 271188897.10 230524133.20 170453029.67 304172189.27
methionine
197817089.93 204177039.10 90696707.86 169354369.23 368738575.70 321167527.10 162615313.80 299493474.17
methioninesulfoxide
7137687.75 11368985.34 81062646.12 7944437.75 17938434.96 12392199.66 121045419.42 11413583.65
myristic acid
663193221.60 652785516.67 407179663.23 397816122.67 550846696.13 361519160.97 450803754.03 809452722.77
N-acetylglucosamine-phosphate
5352780.76 1549332.98 410619.29 880743.51 5549869.47 1602434.08 409626.76 1674847.06
N-acetylglutamate
56432074.82 62508934.55 35628867.94 48082675.36 62738384.49 46410830.62 26077835.79 60471113.08
NAD+
48603162.00 61849476.93 44383101.33 42672071.84 60603502.00 50312321.09 43559288.74 56165323.59
NADH
14822401.37 17120502.08 13115789.94 13708661.07 17055294.15 20330606.95 14197792.71 25450025.31
NADP+
1655206.45 2296160.36 1425923.99 1484701.64 2384667.14 1964962.03 1434990.48 2474036.67
nicotinamide
109983348.47 127293024.20 94247513.65 99444341.08 146412111.97 121105374.97 107422080.41 111549538.40
N-trimethyllysine
479209.36 584784.71 394830.09 432342.59 1244169.66 1073668.05 832652.65 1076005.81
oleic acid
149232232.70 19019524.93 12136632.16 10944772.70 188381337.63 15386079.46 13017522.67 17000622.40
ornithine
2983508.24 2978731.28 2447729.10 2711906.76 4361627.21 4089437.87 4008829.79 3175706.78
orotate
2537245.42 2555276.57 2235213.09 1535026.11 882496.33 951629.91 522068.19 825706.23
palmitic acid
394536868.60 432556290.53 260918874.50 266466850.87 372472225.40 272383189.30 326664305.83 498913538.47
phenylalanine
390740408.93 376956558.53 302929132.47 333750442.50 712342637.90 612907165.37 533275522.50 545981887.03
phosphate
104329086.37 128622938.77 92325680.12 101349488.40 124694974.76 114413807.83 98891510.73 109598865.36
phosphatidylethanolamine
254555.81 344747.24 146646.43 255330.16 223186.36 135791.48 75551.41 226088.21
phosphocholine
3506626201.00 3781557550.00 3213728016.00 3260251318.33 3856668769.67 3524493236.00 3235839022.33 3785079187.33
phosphocreatine
618439.35 857448.55 608758.70 529228.62 660084.66 631974.93 496403.89 725314.81
phosphoenolpyruvate
27258237.94 35588356.67 21066515.16 20170477.98 26210123.54 22740866.72 14399914.41 23181043.34
phosphoglycerate
45220068.65 55927043.42 30707724.00 34122099.43 40945518.14 26594472.63 17729785.90 39948085.81
phosphoribosylamine
579690.32 547100.10 377009.21 365748.58 1952074.06 617297.38 637453.57 1003182.48
phosphorylethanolamine
1053924.46 1520026.86 956135.53 975262.93 1240121.17 986975.45 761693.69 1186656.01
phosphoserine
4637004.40 5809845.14 3402358.91 3287247.11 22768979.81 12714682.32 10951633.16 11331785.40
proline
757226963.63 758593272.87 584890192.37 718029339.57 156540632.63 126663707.07 103154501.66 168124634.20
propionyl-carnitine
3774330.87 3815924.00 3381596.81 2241487.98 2008634.58 2104493.98 1727666.92 1780478.72
PRPP
112721.60 321268.54 130457.60 125690.66 252907.04 241903.88 119154.75 394077.66
pyruvate
12186455.43 16040883.29 10701733.44 13691065.73 10551259.33 21490217.09 14703772.95 13113282.42
quinolinic acid
307525.13 210915.02 211927.73 320546.58 454479.44 386883.47 416570.06 286385.65
riboflavin
291238.86 367781.82 92404.59 281339.89 449595.25 383553.25 137110.02 266051.86
rib/ribul/xylul-ose-phosphate
2938403.28 2674999.27 1507151.27 1383659.63 11687208.54 5312994.68 3191093.87 5620348.48
S-(1;2-Dicarboxyethyl)glutathione
11356573.49 16692508.65 9522901.25 8953097.02 113681809.97 99834243.20 69348808.18 108219037.41
S-(2-Succinyl)-L-cysteine
14656204.92 8644566.79 10265395.98 5595012.83 98152044.03 40781374.54 56630306.57 45552841.86
saccharopine
385767.21 561349.69 321138.72 450440.80 2644304.96 2683326.70 1343129.69 4541634.42
S-adenosyl-homocysteine
1662500.94 2617451.76 1808116.25 1793503.96 1896690.13 2133244.66 1901138.73 2335446.60
S-adenosyl-methionine
8567296.63 11218588.11 6804453.36 9360287.57 9357624.17 11611526.89 7874647.92 11431419.33
SAICAR
1057749.76 2819739.24 1247158.99 1320557.19 24102571.23 17075692.16 10392159.57 15354713.96
sarcosine
12670418.74 14439623.75 12877645.22 12079300.64 15637003.50 14994993.89 14752019.45 16313997.99
sedoheptulose-7-phosphate
654684.35 818619.33 494347.90 555474.72 1440065.27 1055599.96 868566.15 1292193.00
serine
9392572.84 11159039.61 7477672.58 8496307.61 26695252.80 23736486.62 18089083.79 21581204.14
sorbitol
104233154.37 148095500.20 126677887.87 89761747.32 163296665.83 153881326.87 145236777.03 169781754.73
stearic acid
- 177766834.70 129832156.34 119699858.93 - 123252997.61 125077316.40 188275083.97
succinate
79288424.34 90487960.87 58462086.15 54844298.35 204309245.40 168420793.77 127290433.10 135620082.20
taurine
329185513.63 371761516.50 304732614.57 288632441.70 445999132.53 388837457.33 358999043.80 392835800.80
threonine
205146508.53 221823093.47 156050195.97 168298743.00 396117941.40 320382769.43 257738567.67 290770900.47
trifluoromethanesulfonate
36517172.76 47229819.99 32081980.60 30974473.47 45985911.29 39120009.75 30295678.78 43871572.58
tryptophan
20360117.70 24310527.79 10419289.43 17133956.19 43623313.26 34794893.77 18458495.26 32661560.79
tyrosine
90933677.89 110067441.83 67082712.59 78024176.91 208182786.13 162670644.87 121091172.34 157340840.43
UDP
2511416.21 3570378.35 1982006.92 1961855.77 2677216.63 1893744.49 1221853.61 2538316.38
UDP-glucuronic acid
14575507.93 20835291.57 11826900.31 11361914.65 18189137.20 13122016.17 9388432.92 17306739.26
UDP-N-acetylglucosamine
80699846.76 99938335.80 62342624.01 56937148.10 90351877.48 77815140.36 56034797.65 90140272.69
UMP
6604116.56 8514663.14 5337480.42 5612789.01 8386414.66 7940600.73 5436106.71 8387562.31
uric acid
339817.52 225179.70 174223.09 95341.51 190484.03 239721.32 184173.10 128243.15
urocanic acid
4455124.36 3431553.87 4423726.71 5112628.77 4121275.57 2397998.74 2690563.33 3369628.19
UTP
36620767.99 52848841.08 30290961.24 28891443.39 38986893.19 24909668.98 16447501.21 36786754.12
valine
403379118.93 366180858.70 308742073.80 364764905.53 665093847.67 522758350.50 520119951.73 527108636.80
XMP
67541.72 105355.29 25851.99 69150.36 162628.80 134016.00 50802.44 137751.61
xylonic acid
3173314.65 4026162.83 2412234.35 2314842.53 2677174.47 1695418.41 1884564.74 2328500.55
xylulose
1773176.10 1911148.59 854554.65 1373210.52 3477512.16 3075801.31 1485227.34 2848856.62

Factors:

F1Genotype:FH | Tracers used:3,3,3',3'-D4 Cystine
F2Genotype:FH | Tracers used:none
F3Genotype:FH | Tracers used:U-C13 glucose
F4Genotype:FH | Tracers used:U-C13 glutamine
F5Genotype:WT | Tracers used:3,3,3',3'-D4 Cystine
F6Genotype:WT | Tracers used:none
F7Genotype:WT | Tracers used:U-C13 glucose
F8Genotype:WT | Tracers used:U-C13 glutamine
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