Metabolomics Workbench : NIH Data Repository : Analyze Studies

Data for ST002822

(Analysis AN004599): Average values per metabolite and experimental factor (Units:log transformed data)

Metabolite structure	F1	F2	F3	F4
1-methyl-4-imidazoleacetate	0.87	0.34	0.58	-
1-methyl-5-imidazoleacetate	-	-	0.48	0.46
1-methylguanidine	0.13	0.07	0.11	-
1-methylhistamine	0.51	-	0.30	-
1-methylnicotinamide	-	0.23	-	0.30
1-ribosyl-imidazoleacetate*	-	-	-	-
2-aminoheptanoate	0.09	-	0.41	-
2^-deoxyadenosine	0.21	0.18	0.17	-
2^-deoxycytidine	0.19	0.19	0.04	-
2-methylbutyrylcarnitine (C5)	-	-	0.07	0.29
2-methylmalonylcarnitine (C4-DC)	0.58	0.12	0.58	-
2-oxoarginine*	-	-	-	-
3-amino-2-piperidone	-	-	-	-
3-aminoisobutyrate	-	0.12	-	0.14
3-formylindole	0.10	-	0.36	-
3-hydroxyhexanoylcarnitine (1)	-	-	0.79	0.44
3-hydroxyhexanoylcarnitine (2)	-	-	0.83	0.43
3-hydroxyoctanoylcarnitine (1)	-	-	1.14	0.66
3-hydroxyoctanoylcarnitine (2)	-	-	1.19	0.72
3-ureidopropionate	0.08	0.11	-	0.02
4-guanidinobutanoate	-	-	-	0.03
4-hydroxyglutamate	0.06	0.10	0.46	-
4-imidazoleacetate	0.27	0.03	0.29	-
5-aminovalerate	-	-	-	-
5-hydroxylysine	-	0.02	-	0.04
5-methylthioadenosine (MTA)	-	0.08	0.03	0.06
acetylcarnitine (C2)	-	-	0.18	0.17
acetylcholine	0.80	0.23	0.78	-
adenine	-	-	0.31	-
adenosine	-	-	0.80	0.13
adenosine 5^-monophosphate (AMP)	-	-	0.43	0.16
AICA ribonucleotide	0.32	0.13	-	0.27
alanine	-	0.02	0.22	0.03
alanylleucine	0.08	-	-	0.13
anserine	0.58	-	0.69	-
arginine	0.08	0.10	0.03	0.03
ascorbate (Vitamin C)	0.02	0.33	-	0.48
asparagine	0.01	0.09	-	0.12
aspartate	0.40	-	-	0.02
benzoylcarnitine*	0.04	-	0.59	-
beta-alanine	-	0.09	0.12	-
beta-hydroxyisovaleroylcarnitine	0.11	0.17	-	0.03
betaine	0.06	0.20	0.20	-
butenoylcarnitine (C4:1)	-	-	-	-
butyrylcarnitine (C4)	-	0.36	0.61	0.01
carnitine	0.21	0.10	0.14	-
carnosine	0.54	-	0.62	-
C-glycosyltryptophan	0.08	0.16	-	0.24
choline	0.17	0.04	0.14	-
choline phosphate	0.11	0.04	0.09	-
citrulline	0.02	0.10	0.18	-
creatine	-	0.02	0.16	0.01
creatinine	0.00	0.08	0.06	0.04
cystathionine	-	-	-	-
cysteine	0.09	0.11	-	0.01
cysteine-glutathione disulfide	-	-	-	0.16
cysteinylglycine	0.59	0.39	-	0.04
cytidine	0.04	0.08	0.12	0.02
cytidine 5^-monophosphate (5^-CMP)	0.09	0.22	-	0.18
cytosine	-	-	0.17	0.27
deoxycarnitine	0.13	0.08	0.14	-
dihydroxyacetone phosphate (DHAP)	-	-	-	-
dimethylarginine (SDMA + ADMA)	0.10	0.10	0.08	-
dimethylglycine	0.13	0.04	0.17	0.04
dimethyl sulfone	-	-	-	0.04
ergothioneine	-	0.13	0.19	0.35
fructosyllysine	0.28	0.18	-	0.17
gamma-glutamyl-alpha-lysine	0.26	0.44	-	0.14
gamma-glutamyl-epsilon-lysine	0.10	0.28	-	0.22
gamma-glutamylglutamate	0.09	-	-	-
gamma-glutamylglutamine	0.07	0.10	0.30	0.21
gamma-glutamylleucine	0.19	0.23	-	0.04
gamma-glutamylthreonine	0.13	0.10	-	0.11
gamma-glutamylvaline	0.00	0.03	-	-
glutamate	0.16	0.15	-	0.04
glutamate, gamma-methyl ester	0.03	0.07	0.09	-
glutamine	-	0.10	0.04	-
glutathione, oxidized (GSSG)	0.08	0.13	0.05	0.20
glutathione, reduced (GSH)	0.45	0.33	0.10	-
glycerophosphorylcholine (GPC)	0.02	-	0.30	0.28
glycerophosphoserine*	0.00	0.06	-	0.33
glycine	0.01	0.07	0.09	-
glycylleucine	-	-	-	0.17
glycylvaline	-	0.01	-	0.09
guanidinoacetate	-	-	0.27	-
guanine	-	-	-	-
guanosine	-	0.01	0.01	0.00
histamine	0.70	0.42	0.53	0.14
histidine betaine (hercynine)*	0.06	0.34	0.08	0.40
histidine methyl ester	0.14	0.19	-	0.03
homostachydrine*	0.42	0.52	-	0.00
hydroxy-N6,N6,N6-trimethyllysine*	0.22	-	0.25	-
imidazole lactate	-	-	0.06	0.24
imidazole propionate	-	-	-	0.39
inosine 5^-monophosphate (IMP)	0.29	0.30	0.03	-
isobutyrylcarnitine (C4)	-	-	1.04	0.60
isoleucine	0.14	0.25	0.03	0.23
kynurenine	0.10	0.35	0.03	0.14
leucine	0.07	0.10	-	0.04
leucylalanine	0.04	-	-	0.11
leucylglutamine*	0.22	0.17	-	-
leucylglycine	-	-	-	0.05
lysine	0.24	0.24	-	0.01
malonylcarnitine	0.16	0.11	0.06	-
methionine	-	0.01	-	-
methionine sulfoxide	-	-	-	-
N1-methyladenosine	0.23	0.13	-	0.03
(N(1) + N(8))-acetylspermidine	-	0.24	-	0.26
N6-carboxymethyllysine	0.36	0.06	0.04	-
N6-methyllysine	0.10	0.09	0.12	-
N6,N6-dimethyllysine	0.17	0.11	0.04	-
N6,N6,N6-trimethyllysine	0.12	0.21	-	-
N-acetylarginine	-	-	-	0.03
N-acetylasparagine	-	0.02	0.15	-
N-acetyl-aspartyl-glutamate (NAAG)	-	0.40	-	0.58
N-acetylglucosaminylasparagine	-	0.03	-	-
N-acetylglutamine	-	0.13	0.02	0.12
N-acetylhistidine	-	-	-	-
N-acetylmethionine sulfoxide	-	0.02	-	-
N-acetylneuraminate	0.04	0.01	0.08	0.04
N-acetylputrescine	-	0.25	-	0.19
N-acetylserine	-	-	0.27	0.08
nicotinamide	0.11	-	0.18	-
nicotinamide N-oxide	-	0.20	0.04	0.06
nicotinamide ribonucleotide (NMN)	0.45	0.43	0.19	-
nicotinamide riboside	-	0.17	0.09	-
N-methylproline	0.10	-	0.14	-
N-monomethylarginine	0.13	0.08	0.17	-
N,N-dimethylalanine	-	-	-	0.40
N,N-dimethyl-pro-pro	0.43	0.08	0.47	-
N,N,N-trimethyl-5-aminovalerate	-	-	0.54	0.33
N,N,N-trimethyl-alanylproline betaine (TMAP)	0.08	0.06	0.15	-
O-methyltyrosine	0.07	0.18	0.00	0.03
ophthalmate	0.26	0.10	-	-
ornithine	0.10	0.02	-	-
oxindolylalanine	0.22	0.10	-	0.00
pantetheine	0.30	0.10	0.20	-
phenylacetylglycine	-	-	-	0.18
phenylalanine	0.03	0.08	-	0.01
phenylalanylalanine	-	-	-	0.13
phenylalanylglycine	-	-	-	0.12
pipecolate	-	0.19	-	0.31
pro-hydroxy-pro	-	0.12	-	0.45
proline	-	0.03	-	-
prolylglycine	0.09	0.40	0.08	0.23
propionylcarnitine (C3)	0.32	0.08	0.45	0.02
putrescine	-	0.48	-	0.40
pyridoxamine	0.47	0.31	0.13	-
pyridoxamine phosphate	0.27	-	0.13	-
(R)-3-hydroxybutyrylcarnitine	-	-	-	-
(S)-3-hydroxybutyrylcarnitine	-	-	0.50	0.43
S-adenosylmethionine (SAM)	0.06	0.11	-	0.15
serine	-	0.26	0.04	0.21
serotonin	0.04	-	0.62	0.30
spermidine	-	0.29	-	0.24
spermine	0.20	0.18	-	0.14
stachydrine	-	0.14	0.00	0.62
succinylcarnitine (C4-DC)	0.59	0.08	0.43	-
taurine	-	0.02	0.14	0.01
taurocyamine	-	-	-	0.07
thiamin (Vitamin B1)	-	0.03	-	-
thioproline	0.19	0.17	-	0.06
threonine	0.11	0.12	-	0.11
tiglylcarnitine (C5:1-DC)	-	-	-	0.19
trans-4-hydroxyproline	-	-	-	-
tricine	-	-	-	-
triethanolamine	-	-	0.78	0.63
trigonelline (N^-methylnicotinate)	-	-	-	0.34
trimethylamine N-oxide	0.57	0.17	0.25	0.25
trizma acetate	-	-	-	-
tryptophan	0.08	-	0.00	0.20
tyrosine	0.03	0.01	0.15	-
urea	0.04	0.10	-	0.15
valine	0.08	0.25	0.03	0.24
X-10445	-	-	-	-
X-10457	0.21	0.05	0.27	-
X-11381	-	-	0.69	0.48
X-11787	0.10	0.06	0.11	0.14
X-12100	0.23	-	-	-
X-12101	0.46	0.01	0.32	0.14
X-12462	0.29	-	-	-
X-12798	1.38	1.31	0.17	-
X-14056	0.09	0.37	0.29	0.08
X-15136	0.04	0.07	0.08	-
X-15161	-	-	-	0.30
X-15461	0.26	0.16	0.11	-
X-22162	0.15	0.09	-	0.15
X-23171	-	0.02	-	-
X-23587	-	-	-	-
X-23593	-	0.10	-	0.15
X-23639	0.14	0.17	-	0.15
X-23665	-	0.12	-	-
X-23739	-	0.27	-	0.33
X-24224	-	0.06	-	-
X-24425	0.04	0.02	0.31	-
X-24697	-	0.05	-	-
X-25109	-	-	-	-
X-25422	0.06	0.49	-	0.29
X-25855	0.33	0.20	0.25	-
X-25936	-	-	-	0.02
xanthine	-	-	0.03	-

Factors:

F1	Treatment:Heart tissue SLU915 with sham surgery
F2	Treatment:Heart tissue SLU915 with TAC surgery
F3	Treatment:Heart tissue vehicle with sham surgery
F4	Treatment:Heart tissue vehicle with TAC surgery